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A high-throughput imaging and nuclear segmentation analysis protocol for cleared 3D culture models

Scientific reports, 2018-07, Vol.8 (1), p.11135-14, Article 11135

2018

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A High-Content Assay Enables the Automated Screening and Identification of Small Molecules with Specific ALDH1A1-Inhibitory Activity

PloS one, 2017-01, Vol.12 (1), p.e0170937-e0170937

2017

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A Comprehensive Phenotypic Screening Strategy to Identify Modulators of Cargo Translocation by the Bacterial Type IVB Secretion System

mBio, 2022-04, Vol.13 (2), p.e0024022-e0024022

2022

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Correction: A High-Content Assay Enables the Automated Screening and Identification of Small Molecules with Specific ALDH1A1-Inhibitory Activity

PloS one, 2018-05, Vol.13 (5), p.e0197292-e0197292

2018

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Cellular and molecular defects in a patient with Hermansky-Pudlak syndrome type 5

PloS one, 2017-03, Vol.12 (3), p.e0173682-e0173682

2017

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A new homogeneous high-throughput screening assay for profiling compound activity on the human ether-a-go-go-related gene channel

Analytical biochemistry, 2009-11, Vol.394 (1), p.30-38

2009

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Concerted assembly and cloning of multiple DNA segments using in vitro site-specific recombination: functional analysis of multi-segment expression clones

Genome research, 2004-10, Vol.14 (10B), p.2111-2120

2004

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Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors

Bioorganic & medicinal chemistry letters, 2009-07, Vol.19 (13), p.3686-3692

2009

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SNARE-Complex Disassembly by NSF Follows Synaptic-Vesicle Fusion

Proceedings of the National Academy of Sciences - PNAS, 2001-10, Vol.98 (21), p.12233-12238

2001

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A Mutation Inactivating the Mitochondrial Inner Membrane Folate Transporter Creates a Glycine Requirement for Survival of Chinese Hamster Cells

The Journal of biological chemistry, 2004-08, Vol.279 (32), p.33829-33836

2004

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High-throughput fluorescence imaging approaches for drug discovery using in vitro and in vivo three-dimensional models

Expert opinion on drug discovery, 2015-12, Vol.10 (12), p.1347-1361

2015

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Compound screening in cell-based models of tau inclusion formation: Comparison of primary neuron and HEK293 cell assays

The Journal of biological chemistry, 2020-03, Vol.295 (12), p.4001-4013

2020

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High-Throughput Zika Viral Titer Assay for Rapid Screening of Antiviral Drugs

Assay and drug development technologies, 2019-04, Vol.17 (3), p.128-139

2019

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Assessing inhibitors of mutant isocitrate dehydrogenase using a suite of pre-clinical discovery assays

Scientific reports, 2017-10, Vol.7 (1), p.12758-15, Article 12758

2017

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The HIV protease inhibitor, ritonavir, corrects diverse brain phenotypes across development in mouse model of DYT-TOR1A dystonia

Science translational medicine, 2021-08, Vol.13 (607)

2021

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Mammalian Mitochondrial and Cytosolic Folylpolyglutamate Synthetase Maintain the Subcellular Compartmentalization of Folates

The Journal of biological chemistry, 2014-10, Vol.289 (42), p.29386-29396

2014

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A cross-species whole genome siRNA screen in suspension-cultured Chinese hamster ovary cells identifies novel engineering targets

Scientific reports, 2019-06, Vol.9 (1), p.8689-11, Article 8689

2019

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Lung tumor microphysiological system with 3D endothelium to evaluate modulators of T-cell migration

ALTEX, alternatives to animal experimentation, 2023-01, Vol.40 (4), p.649

2023

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Connecting Neuronal Cell Protective Pathways and Drug Combinations in a Huntington’s Disease Model through the Application of Quantitative Systems Pharmacology

Scientific reports, 2017-12, Vol.7 (1), p.17803-16, Article 17803

2017

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Exploring Drug Dosing Regimens In Vitro Using Real-Time 3D Spheroid Tumor Growth Assays

SLAS discovery, 2017-06, Vol.22 (5), p.537-546

2017

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Identification of quaternary ammonium compounds as potent inhibitors of hERG potassium channels

Toxicology and applied pharmacology, 2011-05, Vol.252 (3), p.250-258

2011

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RNAi High-Throughput Screening of Single- and Multi-Cell-Type Tumor Spheroids: A Comprehensive Analysis in Two and Three Dimensions

SLAS discovery, 2017-06, Vol.22 (5), p.525-536

2017

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Automated High-Content Screening for Compounds That Disassemble the Perinucleolar Compartment

Journal of biomolecular screening, 2009-10, Vol.14 (9), p.1045-1053

2009

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A cell-based PDE4 assay in 1536-well plate format for high-throughput screening

Journal of biomolecular screening, 2008-08, Vol.13 (7), p.609-618

2008

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A high-throughput imaging and nuclear segmentation analysis protocol for cleared 3D culture models

A High-Content Assay Enables the Automated Screening and Identification of Small Molecules with Specific ALDH1A1-Inhibitory Activity

A Comprehensive Phenotypic Screening Strategy to Identify Modulators of Cargo Translocation by the Bacterial Type IVB Secretion System

Inhibition of PIP4Kγ ameliorates the pathological effects of mutant huntingtin protein

Correction: A High-Content Assay Enables the Automated Screening and Identification of Small Molecules with Specific ALDH1A1-Inhibitory Activity

Cellular and molecular defects in a patient with Hermansky-Pudlak syndrome type 5

A new homogeneous high-throughput screening assay for profiling compound activity on the human ether-a-go-go-related gene channel

Concerted assembly and cloning of multiple DNA segments using in vitro site-specific recombination: functional analysis of multi-segment expression clones

Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors

SNARE-Complex Disassembly by NSF Follows Synaptic-Vesicle Fusion

A Mutation Inactivating the Mitochondrial Inner Membrane Folate Transporter Creates a Glycine Requirement for Survival of Chinese Hamster Cells

High-throughput fluorescence imaging approaches for drug discovery using in vitro and in vivo three-dimensional models

Compound screening in cell-based models of tau inclusion formation: Comparison of primary neuron and HEK293 cell assays

High-Throughput Zika Viral Titer Assay for Rapid Screening of Antiviral Drugs

Assessing inhibitors of mutant isocitrate dehydrogenase using a suite of pre-clinical discovery assays

The HIV protease inhibitor, ritonavir, corrects diverse brain phenotypes across development in mouse model of DYT-TOR1A dystonia

Mammalian Mitochondrial and Cytosolic Folylpolyglutamate Synthetase Maintain the Subcellular Compartmentalization of Folates

A cross-species whole genome siRNA screen in suspension-cultured Chinese hamster ovary cells identifies novel engineering targets

Lung tumor microphysiological system with 3D endothelium to evaluate modulators of T-cell migration

Connecting Neuronal Cell Protective Pathways and Drug Combinations in a Huntington’s Disease Model through the Application of Quantitative Systems Pharmacology

Exploring Drug Dosing Regimens In Vitro Using Real-Time 3D Spheroid Tumor Growth Assays

Identification of quaternary ammonium compounds as potent inhibitors of hERG potassium channels

RNAi High-Throughput Screening of Single- and Multi-Cell-Type Tumor Spheroids: A Comprehensive Analysis in Two and Three Dimensions

Automated High-Content Screening for Compounds That Disassemble the Perinucleolar Compartment

A cell-based PDE4 assay in 1536-well plate format for high-throughput screening

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