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A high-throughput imaging and nuclear segmentation analysis protocol for cleared 3D culture models

Scientific reports, 2018-07, Vol.8 (1), p.11135-14, Article 11135

2018

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A High-Content Assay Enables the Automated Screening and Identification of Small Molecules with Specific ALDH1A1-Inhibitory Activity

PloS one, 2017-01, Vol.12 (1), p.e0170937-e0170937

2017

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Correction: A High-Content Assay Enables the Automated Screening and Identification of Small Molecules with Specific ALDH1A1-Inhibitory Activity

PloS one, 2018-05, Vol.13 (5), p.e0197292-e0197292

2018

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A Comprehensive Phenotypic Screening Strategy to Identify Modulators of Cargo Translocation by the Bacterial Type IVB Secretion System

mBio, 2022-04, Vol.13 (2), p.e0024022-e0024022

2022

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Cellular and molecular defects in a patient with Hermansky-Pudlak syndrome type 5

PloS one, 2017-03, Vol.12 (3), p.e0173682-e0173682

2017

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High-throughput fluorescence imaging approaches for drug discovery using in vitro and in vivo three-dimensional models

Expert opinion on drug discovery, 2015-12, Vol.10 (12), p.1347-1361

2015

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Compound screening in cell-based models of tau inclusion formation: Comparison of primary neuron and HEK293 cell assays

The Journal of biological chemistry, 2020-03, Vol.295 (12), p.4001-4013

2020

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High-Throughput Zika Viral Titer Assay for Rapid Screening of Antiviral Drugs

Assay and drug development technologies, 2019-04, Vol.17 (3), p.128

2019

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Assessing inhibitors of mutant isocitrate dehydrogenase using a suite of pre-clinical discovery assays

Scientific reports, 2017-10, Vol.7 (1), p.12758-15, Article 12758

2017

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The HIV protease inhibitor, ritonavir, corrects diverse brain phenotypes across development in mouse model of DYT-TOR1A dystonia

Science translational medicine, 2021-08, Vol.13 (607)

2021

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A cross-species whole genome siRNA screen in suspension-cultured Chinese hamster ovary cells identifies novel engineering targets

Scientific reports, 2019-06, Vol.9 (1), p.8689-11, Article 8689

2019

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Mammalian Mitochondrial and Cytosolic Folylpolyglutamate Synthetase Maintain the Subcellular Compartmentalization of Folates

The Journal of biological chemistry, 2014-10, Vol.289 (42), p.29386-29396

2014

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Neural stem cells for disease modeling and evaluation of therapeutics for infantile (CLN1/PPT1) and late infantile (CLN2/TPP1) neuronal ceroid lipofuscinoses

Orphanet journal of rare diseases, 2018-04, Vol.13 (1), p.54-54, Article 54

2018

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A new homogeneous high-throughput screening assay for profiling compound activity on the human ether-a-go-go-related gene channel

Analytical biochemistry, 2009-11, Vol.394 (1), p.30-38

2009

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Lung tumor microphysiological system with 3D endothelium to evaluate modulators of T-cell migration

ALTEX, alternatives to animal experimentation, 2023-01, Vol.40 (4), p.649

2023

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Connecting Neuronal Cell Protective Pathways and Drug Combinations in a Huntington's Disease Model through the Application of Quantitative Systems Pharmacology

Scientific reports, 2017-12, Vol.7 (1), p.17803-16, Article 17803

2017

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Concerted assembly and cloning of multiple DNA segments using in vitro site-specific recombination: functional analysis of multi-segment expression clones

Genome research, 2004-10, Vol.14 (10B), p.2111

2004

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Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors

Bioorganic & medicinal chemistry letters, 2009-07, Vol.19 (13), p.3686-3692

2009

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Exploring Drug Dosing Regimens In Vitro Using Real-Time 3D Spheroid Tumor Growth Assays

SLAS discovery, 2017-06, Vol.22 (5), p.537-546

2017

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Identification of quaternary ammonium compounds as potent inhibitors of hERG potassium channels

Toxicology and applied pharmacology, 2011-05, Vol.252 (3), p.250-258

2011

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RNAi High-Throughput Screening of Single- and Multi-Cell-Type Tumor Spheroids: A Comprehensive Analysis in Two and Three Dimensions

SLAS discovery, 2017-06, Vol.22 (5), p.525-536

2017

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SNARE-Complex Disassembly by NSF Follows Synaptic-Vesicle Fusion

Proceedings of the National Academy of Sciences - PNAS, 2001-10, Vol.98 (21), p.12233-12238

2001

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A Mutation Inactivating the Mitochondrial Inner Membrane Folate Transporter Creates a Glycine Requirement for Survival of Chinese Hamster Cells

The Journal of biological chemistry, 2004-08, Vol.279 (32), p.33829-33836

2004

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Automated High-Content Screening for Compounds That Disassemble the Perinucleolar Compartment

Journal of biomolecular screening, 2009-10, Vol.14 (9), p.1045-1053

2009

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A high-throughput imaging and nuclear segmentation analysis protocol for cleared 3D culture models

A High-Content Assay Enables the Automated Screening and Identification of Small Molecules with Specific ALDH1A1-Inhibitory Activity

Correction: A High-Content Assay Enables the Automated Screening and Identification of Small Molecules with Specific ALDH1A1-Inhibitory Activity

A Comprehensive Phenotypic Screening Strategy to Identify Modulators of Cargo Translocation by the Bacterial Type IVB Secretion System

Cellular and molecular defects in a patient with Hermansky-Pudlak syndrome type 5

Inhibition of PIP4Kγ ameliorates the pathological effects of mutant huntingtin protein

High-throughput fluorescence imaging approaches for drug discovery using in vitro and in vivo three-dimensional models

Compound screening in cell-based models of tau inclusion formation: Comparison of primary neuron and HEK293 cell assays

High-Throughput Zika Viral Titer Assay for Rapid Screening of Antiviral Drugs

Assessing inhibitors of mutant isocitrate dehydrogenase using a suite of pre-clinical discovery assays

The HIV protease inhibitor, ritonavir, corrects diverse brain phenotypes across development in mouse model of DYT-TOR1A dystonia

A cross-species whole genome siRNA screen in suspension-cultured Chinese hamster ovary cells identifies novel engineering targets

Mammalian Mitochondrial and Cytosolic Folylpolyglutamate Synthetase Maintain the Subcellular Compartmentalization of Folates

Neural stem cells for disease modeling and evaluation of therapeutics for infantile (CLN1/PPT1) and late infantile (CLN2/TPP1) neuronal ceroid lipofuscinoses

A new homogeneous high-throughput screening assay for profiling compound activity on the human ether-a-go-go-related gene channel

Lung tumor microphysiological system with 3D endothelium to evaluate modulators of T-cell migration

Connecting Neuronal Cell Protective Pathways and Drug Combinations in a Huntington's Disease Model through the Application of Quantitative Systems Pharmacology

Concerted assembly and cloning of multiple DNA segments using in vitro site-specific recombination: functional analysis of multi-segment expression clones

Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors

Exploring Drug Dosing Regimens In Vitro Using Real-Time 3D Spheroid Tumor Growth Assays

Identification of quaternary ammonium compounds as potent inhibitors of hERG potassium channels

RNAi High-Throughput Screening of Single- and Multi-Cell-Type Tumor Spheroids: A Comprehensive Analysis in Two and Three Dimensions

SNARE-Complex Disassembly by NSF Follows Synaptic-Vesicle Fusion

A Mutation Inactivating the Mitochondrial Inner Membrane Folate Transporter Creates a Glycine Requirement for Survival of Chinese Hamster Cells

Automated High-Content Screening for Compounds That Disassemble the Perinucleolar Compartment

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