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Indoleamides are active against drug-resistant Mycobacterium tuberculosis

Nature communications, 2013-12, Vol.4 (1), Article 2907

2013

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Preliminary Structure–Activity Relationships and Biological Evaluation of Novel Antitubercular Indolecarboxamide Derivatives Against Drug-Susceptible and Drug-Resistant Mycobacterium tuberculosis Strains

Journal of medicinal chemistry, 2013-05, Vol.56 (10), p.4093-4103

2013

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Synthesis of 7-Desmethyl Analogs of (+)- and (−)-Huperzine A

Heterocycles, 2015, Vol.91 (12), p.2285

2015

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Identification and Development of Novel Inhibitors of Toxoplasma gondii Enoyl Reductase

Journal of medicinal chemistry, 2010-09, Vol.53 (17), p.6287-6300

2010

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Pyrido[1,2-a]benzimidazole-Based Agents Active Against Tuberculosis (TB), Multidrug-Resistant (MDR) TB and Extensively Drug-Resistant (XDR) TB

ChemMedChem, 2011-02, Vol.6 (2), p.334-342

2011

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Targeting EphA2 in Bladder Cancer Using a Novel Antibody-Directed Nanotherapeutic

Pharmaceutics, 2020-10, Vol.12 (10), p.996

2020

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Indoleamides are active against drug-resistant Mycobacterium tuberculosis

Nature communications, 2013-12, Vol.4, p.2907-2907

2013

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In Pursuit of Natural Product Leads: Synthesis and Biological Evaluation of 2-[3-hydroxy-2-[(3-hydroxypyridine-2-carbonyl)amino]phenyl]benzoxazole-4-carboxylic acid (A-33853) and Its Analogues: Discovery of N-(2-Benzoxazol-2-ylphenyl)benzamides as Novel Antileishmanial Chemotypes

Journal of medicinal chemistry, 2008-12, Vol.51 (23), p.7344-7347

2008

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Design and Synthesis of Aryl Ether Inhibitors of the Bacillus Anthracis Enoyl-ACP Reductase

ChemMedChem, 2008-08, Vol.3 (8), p.1250-1268

2008

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Structural analogs of huperzine A improve survival in guinea pigs exposed to soman

Bioorganic & medicinal chemistry letters, 2013-03, Vol.23 (5), p.1544-1547

2013

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Design and synthesis of 2-pyridones as novel inhibitors of the Bacillus anthracis enoyl-ACP reductase

Bioorganic & medicinal chemistry, 2008-06, Vol.18 (12), p.3565-3569

2008

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Natural product leads for drug discovery: Isolation, synthesis and biological evaluation of 6-cyano-5-methoxyindolo[2,3- a]carbazole based ligands as antibacterial agents

Bioorganic & medicinal chemistry, 2009-10, Vol.17 (20), p.7126-7130

2009

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Technology Transfer and Process Development of Danicopan to Enable Process Validation

Organic process research & development, 2024-06

2024

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Abstract 4711: Immunomodulatory effects of an EphA2-targeted docetaxel antibody-directed nanotherapeutic and synergistic combination with PD-1 inhibitor

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.4711-4711

2017

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Abstract 3096: Mechanisms of synergy of carboplatin and an EphA2-targeted docetaxel antibody-directed nanotherapeutic

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.3096-3096

2017

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Mitochondrial matrix metalloproteinase activation decreases myocyte contractility in hyperhomocysteinemia

American journal of physiology. Heart and circulatory physiology, 2008-08, Vol.295 (2), p.H890-H897

2008

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Cleavage of Si-Ar bond vs Si-Me bond: a remarkable counterion effect on reactivity

Chemical communications (Cambridge, England), 2002-09 (17), p.1924-1925

2002

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Mitochondrial matrix metalloproteinase activation decreases myocyte contractility in hyperhomocysteinemia

American journal of physiology. Heart and circulatory physiology, 2008, Vol.64 (2), p.890-897

2008

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Cleavage of Si–Ar bond vs Si–Me bond: a remarkable counterion effect on reactivity

Chemical communications (Cambridge, England), 2002 (17), p.1924-1925

2002

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Contra-intuitive stereocontrol: endo-selective nucleophilic additions on an arene–tricarbonylchromium template

Journal of organometallic chemistry, 2001-04, Vol.624 (1), p.18-25

2001

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Cleavage of Si-Ar Bond vs. Si-Me Bond: A Remarkable Counterion Effect on Reactivity

ChemInform, 2003-01, Vol.34 (2), p.no-no

2003

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ChemInform Abstract: Contra-Intuitive Stereocontrol: endo-Selective Nucleophilic Additions on an Arene-Tricarbonylchromium Template

ChemInform, 2001-08, Vol.32 (32), p.no-no

2001

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Indoleamides are active against drug-resistant Mycobacterium tuberculosis

Preliminary Structure–Activity Relationships and Biological Evaluation of Novel Antitubercular Indolecarboxamide Derivatives Against Drug-Susceptible and Drug-Resistant Mycobacterium tuberculosis Strains

Synthesis of 7-Desmethyl Analogs of (+)- and (−)-Huperzine A

Identification and Development of Novel Inhibitors of Toxoplasma gondii Enoyl Reductase

Pyrido[1,2-a]benzimidazole-Based Agents Active Against Tuberculosis (TB), Multidrug-Resistant (MDR) TB and Extensively Drug-Resistant (XDR) TB

Targeting EphA2 in Bladder Cancer Using a Novel Antibody-Directed Nanotherapeutic

Indoleamides are active against drug-resistant Mycobacterium tuberculosis

In Pursuit of Natural Product Leads: Synthesis and Biological Evaluation of 2-[3-hydroxy-2-[(3-hydroxypyridine-2-carbonyl)amino]phenyl]benzoxazole-4-carboxylic acid (A-33853) and Its Analogues: Discovery of N-(2-Benzoxazol-2-ylphenyl)benzamides as Novel Antileishmanial Chemotypes

Design and Synthesis of Aryl Ether Inhibitors of the Bacillus Anthracis Enoyl-ACP Reductase

Structural analogs of huperzine A improve survival in guinea pigs exposed to soman

Design and synthesis of 2-pyridones as novel inhibitors of the Bacillus anthracis enoyl-ACP reductase

Natural product leads for drug discovery: Isolation, synthesis and biological evaluation of 6-cyano-5-methoxyindolo[2,3- a]carbazole based ligands as antibacterial agents

Technology Transfer and Process Development of Danicopan to Enable Process Validation

Abstract 4711: Immunomodulatory effects of an EphA2-targeted docetaxel antibody-directed nanotherapeutic and synergistic combination with PD-1 inhibitor

Abstract 3096: Mechanisms of synergy of carboplatin and an EphA2-targeted docetaxel antibody-directed nanotherapeutic

Antitumour activity and tolerability of an EphA2-targeted nanotherapeutic in multiple mouse models

Mitochondrial matrix metalloproteinase activation decreases myocyte contractility in hyperhomocysteinemia

Cleavage of Si-Ar bond vs Si-Me bond: a remarkable counterion effect on reactivity

Mitochondrial matrix metalloproteinase activation decreases myocyte contractility in hyperhomocysteinemia

Cleavage of Si–Ar bond vs Si–Me bond: a remarkable counterion effect on reactivity

Contra-intuitive stereocontrol: endo-selective nucleophilic additions on an arene–tricarbonylchromium template

Cleavage of Si-Ar Bond vs. Si-Me Bond: A Remarkable Counterion Effect on Reactivity

ChemInform Abstract: Contra-Intuitive Stereocontrol: endo-Selective Nucleophilic Additions on an Arene-Tricarbonylchromium Template

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