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The Aldo-Keto Reductase Superfamily and its Role in Drug Metabolism and Detoxification

Drug metabolism reviews, 2008-01, Vol.40 (4), p.553-624

2008

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Muscle-Brain crosstalk in cognitive impairment

Frontiers in aging neuroscience, 2023-07, Vol.15, p.1221653-1221653

2023

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Nampt activator P7C3 ameliorates diabetes and improves skeletal muscle function modulating cell metabolism and lipid mediators

Journal of cachexia, sarcopenia and muscle, 2022-04, Vol.13 (2), p.1177-1196

2022

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NALP-3 inflammasome silencing attenuates ceramide-induced transepithelial permeability

Journal of cellular physiology, 2012-09, Vol.227 (9), p.3310-3316

2012

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Novel biomarkers of inflammation in heart failure with preserved ejection fraction: analysis from a large prospective cohort study

BMC cardiovascular disorders, 2022-05, Vol.22 (1), p.221-221, Article 221

2022

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Transformational Applications of Human Cardiac Organoids in Cardiovascular Diseases

Frontiers in cell and developmental biology, 2022-06, Vol.10, p.936084

2022

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Chemokine/ITGA4 Interaction Directs iPSC-Derived Myogenic Progenitor Migration to Injury Sites in Aging Muscle for Regeneration

Cells (Basel, Switzerland), 2023-07, Vol.12 (14), p.1837

2023

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MicroRNA-301a mediated regulation of Kv4.2 in diabetes: identification of key modulators

PloS one, 2013-04, Vol.8 (4), p.e60545-e60545

2013

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Extracellular Vesicles from iPSC derived Muscle Progenitor Cells Rejuvenate the Dysfunctional Muscle Stem Cells during Aging

The FASEB journal, 2022-05, Vol.36 (S1), p.n/a

2022

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Genetic deletion of Kvβ2 (AKR6) causes loss of muscle function and increased inflammation in mice

Frontiers in aging, 2023-06, Vol.4, p.1175510

2023

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NAD+ centric mechanisms and molecular determinants of skeletal muscle disease and aging

Molecular and cellular biochemistry, 2022-06, Vol.477 (6), p.1829-1848

2022

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Corticosteroids and aldose reductase inhibitor Epalrestat modulates cardiac action potential via Kvβ1.1 (AKR6A8) subunit of voltage-gated potassium channel

Molecular and cellular biochemistry, 2017-12, Vol.436 (1-2), p.71-78

2017

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Deletion of Kvβ2 (AKR6) Attenuates Isoproterenol Induced Cardiac Injury with Links to Solute Carrier Transporter SLC41a3 and Circadian Clock Genes

Metabolites, 2021-03, Vol.11 (4), p.201

2021

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P7C3 ameliorates barium chloride‐induced skeletal muscle injury activating transcriptomic and epigenetic modulation of myogenic regulatory factors

Journal of cellular physiology, 2024-06, Vol.239 (9)

2024

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Regulation of Ion Channels by Pyridine Nucleotides

Circulation research, 2013-02, Vol.112 (4), p.721-741

2013

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Smad7 interrupts TGF-β signaling in intestinal macrophages and promotes inflammatory activation of these cells during necrotizing enterocolitis

Pediatric research, 2016-06, Vol.79 (6), p.951-961

2016

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Development and testing of nanoparticles delivery for P7C3 small molecule using injury models

Molecular and cellular biochemistry, 2024-09, Vol.479 (9), p.2429-2445

2024

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Catalytic reduction of carbonyl groups in oxidized PAPC by Kvβ2 (AKR6)

Chemico-biological interactions, 2011-05, Vol.191 (1), p.255-260

2011

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Cardioprotective Effects of 1-(3,6-Dibromo-carbazol-9-yl)-3-Phenylamino-Propan-2-Ol in Diabetic Hearts via Nicotinamide Phosphoribosyltransferase Activation

The Journal of pharmacology and experimental therapeutics, 2022-08, Vol.382 (2), p.233-245

2022

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Impact of Metformin on Statin Persistence: a Post Hoc Analysis of a Large Randomized Controlled Trial

Journal of general internal medicine : JGIM, 2022-01, Vol.37 (1), p.277-279

2022

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Kvβ1.1 (AKR6A8) senses pyridine nucleotide changes in the mouse heart and modulates cardiac electrical activity

American journal of physiology. Heart and circulatory physiology, 2017-03, Vol.312 (3), p.H571-H583

2017

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Association of Common Foods with Inflammation and Mortality: Analysis from a Large Prospective Cohort Study

Journal of medicinal food, 2024-03, Vol.27 (3), p.267-274

2024

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Kinetics of nucleotide binding to the β-subunit (AKR6A2) of the voltage-gated potassium (Kv) channel

Chemico-biological interactions, 2009-03, Vol.178 (1), p.165-170

2009

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Metabolic regulation of Kv channels and cardiac repolarization by Kvβ2 subunits

Journal of molecular and cellular cardiology, 2019-12, Vol.137, p.93-106

2019

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Combined Endurance and Resistance Exercise Mitigates Age-Associated Cardiac Dysfunction

Advanced biology, 2024-05, p.e2400137-e2400137

2024

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The Aldo-Keto Reductase Superfamily and its Role in Drug Metabolism and Detoxification

Muscle-Brain crosstalk in cognitive impairment

Nampt activator P7C3 ameliorates diabetes and improves skeletal muscle function modulating cell metabolism and lipid mediators

NALP-3 inflammasome silencing attenuates ceramide-induced transepithelial permeability

Novel biomarkers of inflammation in heart failure with preserved ejection fraction: analysis from a large prospective cohort study

Transformational Applications of Human Cardiac Organoids in Cardiovascular Diseases

Chemokine/ITGA4 Interaction Directs iPSC-Derived Myogenic Progenitor Migration to Injury Sites in Aging Muscle for Regeneration

MicroRNA-301a mediated regulation of Kv4.2 in diabetes: identification of key modulators

Extracellular Vesicles from iPSC derived Muscle Progenitor Cells Rejuvenate the Dysfunctional Muscle Stem Cells during Aging

Genetic deletion of Kvβ2 (AKR6) causes loss of muscle function and increased inflammation in mice

NAD+ centric mechanisms and molecular determinants of skeletal muscle disease and aging

Corticosteroids and aldose reductase inhibitor Epalrestat modulates cardiac action potential via Kvβ1.1 (AKR6A8) subunit of voltage-gated potassium channel

Deletion of Kvβ2 (AKR6) Attenuates Isoproterenol Induced Cardiac Injury with Links to Solute Carrier Transporter SLC41a3 and Circadian Clock Genes

P7C3 ameliorates barium chloride‐induced skeletal muscle injury activating transcriptomic and epigenetic modulation of myogenic regulatory factors

Regulation of Ion Channels by Pyridine Nucleotides

Smad7 interrupts TGF-β signaling in intestinal macrophages and promotes inflammatory activation of these cells during necrotizing enterocolitis

Development and testing of nanoparticles delivery for P7C3 small molecule using injury models

Catalytic reduction of carbonyl groups in oxidized PAPC by Kvβ2 (AKR6)

Cardioprotective Effects of 1-(3,6-Dibromo-carbazol-9-yl)-3-Phenylamino-Propan-2-Ol in Diabetic Hearts via Nicotinamide Phosphoribosyltransferase Activation

Impact of Metformin on Statin Persistence: a Post Hoc Analysis of a Large Randomized Controlled Trial

Kvβ1.1 (AKR6A8) senses pyridine nucleotide changes in the mouse heart and modulates cardiac electrical activity

Association of Common Foods with Inflammation and Mortality: Analysis from a Large Prospective Cohort Study

Kinetics of nucleotide binding to the β-subunit (AKR6A2) of the voltage-gated potassium (Kv) channel

Metabolic regulation of Kv channels and cardiac repolarization by Kvβ2 subunits

Combined Endurance and Resistance Exercise Mitigates Age-Associated Cardiac Dysfunction

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