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Pharmacokinetics of ‘party pill’ drug N-benzylpiperazine (BZP) in healthy human participants

Forensic science international, 2009-04, Vol.186 (1), p.63-67

2009

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Comparative bioactivation of the novel anti‐tuberculosis agent PA‐824 in Mycobacteria and a subcellular fraction of human liver

British journal of pharmacology, 2011-01, Vol.162 (1), p.226-236

2011

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Bioavailability and pharmacokinetics of a praziquantel bolus in kingfish Seriola lalandi

Diseases of aquatic organisms, 2006-04, Vol.69 (2-3), p.233-238

2006

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Measuring antibiotic levels and their relationship with the microbiome in chronic rhinosinusitis

Journal of laryngology and otology, 2019-10, Vol.133 (10), p.862-866

2019

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Effect of dose escalation on multiple dose pharmacokinetics of orally administered praziquantel in kingfish Seriola lalandi

Aquaculture, 2006-12, Vol.261 (4), p.1168-1174

2006

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Can in vitro drug metabolism studies with human tissue replace in vivo animal studies?

Environmental toxicology and pharmacology, 2006-02, Vol.21 (2), p.184-190

2006

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Reversible binding of the novel anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid to plasma proteins and its distribution into blood cells in various species

Journal of pharmacy and pharmacology, 2001-04, Vol.53 (4), p.463-471

2001

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Comparison of the metabolism and toxicity of dapsone in rat, mouse and man

The Journal of pharmacology and experimental therapeutics, 1997-11, Vol.283 (2), p.817

1997

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N‐Hydroxylation of dapsone by multiple enzymes of cytochrome P450: implications for inhibition of haemotoxicity

British journal of clinical pharmacology, 1995-12, Vol.40 (6), p.531-538

1995

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Effect of Disposition of Mannich Antimalarial Agents on Their Pharmacology and Toxicology

Antimicrobial Agents and Chemotherapy, 1998-09, Vol.42 (9), p.2410-2416

1998

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Species differences in the metabolism of the antitumour agent 5,6-dimethylxanthenone-4-acetic acid in vitro : implications for prediction of metabolic interactions in vivo

Xenobiotica, 2002-02, Vol.32 (2), p.87-107

2002

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Identification and reactivity of the major metabolite (ß-1-glucuronide) of the anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in humans

Xenobiotica, 2001-05, Vol.31 (5), p.277-293

2001

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Cimetidine improves the therapeutic/toxic ratio of dapsone in patients on chronic dapsone therapy

British journal of dermatology (1951), 1995-02, Vol.132 (2), p.257-262

1995

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Intracellular glutathione in the peripheral blood cells of HIV-infected patients : failure to show a deficiency

AIDS (London), 1996-05, Vol.10 (5), p.501-507

1996

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A highly sensitive fluorescent microplate method for the determination of UDP-glucuronosyl transferase activity in tissues and placental cell lines

Drug metabolism and disposition, 2000-10, Vol.28 (10), p.1184

2000

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An investigation of the formation of cytotoxic, genotoxic, protein-reactive and stable metabolites from naphthalene by human liver microsomes

Biochemical pharmacology, 1993-11, Vol.46 (9), p.1529-1538

1993

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Identification of the human liver cytochrome P450 isoenzyme responsible for the 6-methylhydroxylation of the novel anticancer drug 5,6-dimethylxanthenone-4-acetic acid

Drug metabolism and disposition, 2000-12, Vol.28 (12), p.1449

2000

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An investigation of the role of metabolism in dapsone‐induced methaemoglobinaemia using a two compartment in vitro test system

British journal of clinical pharmacology, 1990-12, Vol.30 (6), p.829-838

1990

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Structural basis for the haemotoxicity of dapsone: the importance of the sulphonyl group

Toxicology (Amsterdam), 1997-02, Vol.117 (1), p.1-11

1997

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Evaluation of the generation of genotoxic and cytotoxic metabolites of benzo[a]pyrene, aflatoxin B1, naphthalene and tamoxifen using human liver microsomes and human lymphocytes

Human & experimental toxicology, 1995-06, Vol.14 (6), p.507-515

1995

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The use of a three compartment in vitro model to investigate the role of hepatic drug metabolism in drug‐induced blood dyscrasias

British journal of clinical pharmacology, 1993-07, Vol.36 (1), p.31-38

1993

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Bioactivation and bioinactivation of drugs and drug metabolites: Relevance to adverse drug reactions

THIRD INTERNATIONAL CONFERENCE ON PRACTICAL IN VITRO TOXICOLOGY, 1994-08, Vol.8 (4), p.613-621

1994

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The bioactivation of amodiaquine by human polymorphonuclear leucocytes in vitro: Chemical mechanisms and the effects of fluorine substitution

Biochemical pharmacology, 1995-09, Vol.50 (7), p.1113-1119

1995

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An Investigation into the Haematological Toxicity of Structural Analogues of Dapsone In-vivo and In-vitro

Journal of pharmacy and pharmacology, 1991-11, Vol.43 (11), p.779-784

1991

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Gonadal Influence on the Metabolism and Haematological Toxicity of Dapsone in the Rat

Journal of pharmacy and pharmacology, 1990-10, Vol.42 (10), p.698-703

1990

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Pharmacokinetics of ‘party pill’ drug N-benzylpiperazine (BZP) in healthy human participants

Comparative bioactivation of the novel anti‐tuberculosis agent PA‐824 in Mycobacteria and a subcellular fraction of human liver

Bioavailability and pharmacokinetics of a praziquantel bolus in kingfish Seriola lalandi

Measuring antibiotic levels and their relationship with the microbiome in chronic rhinosinusitis

Effect of dose escalation on multiple dose pharmacokinetics of orally administered praziquantel in kingfish Seriola lalandi

Can in vitro drug metabolism studies with human tissue replace in vivo animal studies?

Reversible binding of the novel anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid to plasma proteins and its distribution into blood cells in various species

Comparison of the metabolism and toxicity of dapsone in rat, mouse and man

N‐Hydroxylation of dapsone by multiple enzymes of cytochrome P450: implications for inhibition of haemotoxicity

Effect of Disposition of Mannich Antimalarial Agents on Their Pharmacology and Toxicology

Species differences in the metabolism of the antitumour agent 5,6-dimethylxanthenone-4-acetic acid in vitro : implications for prediction of metabolic interactions in vivo

Identification and reactivity of the major metabolite (ß-1-glucuronide) of the anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in humans

Cimetidine improves the therapeutic/toxic ratio of dapsone in patients on chronic dapsone therapy

Intracellular glutathione in the peripheral blood cells of HIV-infected patients : failure to show a deficiency

A highly sensitive fluorescent microplate method for the determination of UDP-glucuronosyl transferase activity in tissues and placental cell lines

An investigation of the formation of cytotoxic, genotoxic, protein-reactive and stable metabolites from naphthalene by human liver microsomes

Identification of the human liver cytochrome P450 isoenzyme responsible for the 6-methylhydroxylation of the novel anticancer drug 5,6-dimethylxanthenone-4-acetic acid

An investigation of the role of metabolism in dapsone‐induced methaemoglobinaemia using a two compartment in vitro test system

Structural basis for the haemotoxicity of dapsone: the importance of the sulphonyl group

Evaluation of the generation of genotoxic and cytotoxic metabolites of benzo[a]pyrene, aflatoxin B1, naphthalene and tamoxifen using human liver microsomes and human lymphocytes

The use of a three compartment in vitro model to investigate the role of hepatic drug metabolism in drug‐induced blood dyscrasias

Bioactivation and bioinactivation of drugs and drug metabolites: Relevance to adverse drug reactions

The bioactivation of amodiaquine by human polymorphonuclear leucocytes in vitro: Chemical mechanisms and the effects of fluorine substitution

An Investigation into the Haematological Toxicity of Structural Analogues of Dapsone In-vivo and In-vitro

Gonadal Influence on the Metabolism and Haematological Toxicity of Dapsone in the Rat

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