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Current Availability of Stem Cell-Based In Vitro Methods for Developmental Neurotoxicity (DNT) Testing

Toxicological sciences, 2018-09, Vol.165 (1), p.21-30

2018

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Characterization of Skin Aging–Associated Secreted Proteins (SAASP) Produced by Dermal Fibroblasts Isolated from Intrinsically Aged Human Skin

Journal of investigative dermatology, 2015-08, Vol.135 (8), p.1954-1968

2015

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Development of the Concept for Stem Cell-Based Developmental Neurotoxicity Evaluation

Toxicological sciences, 2018-09, Vol.165 (1), p.14-20

2018

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The Human Induced Pluripotent Stem Cell Test as an Alternative Method for Embryotoxicity Testing

International journal of molecular sciences, 2022-03, Vol.23 (6), p.3295

2022

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Age, gender and UV-exposition related effects on gene expression in in vivo aged short term cultivated human dermal fibroblasts

PloS one, 2017-05, Vol.12 (5), p.e0175657-e0175657

2017

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Neurodevelopmental toxicity assessment of flame retardants using a human DNT in vitro testing battery

Cell biology and toxicology, 2022-10, Vol.38 (5), p.781-807

2022

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Academic application of Good Cell Culture Practice for induced pluripotent stem cells

ALTEX, alternatives to animal experimentation, 2021-01, Vol.38 (4), p.595-614

2021

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MicroRNA-15b regulates mitochondrial ROS production and the senescence-associated secretory phenotype through sirtuin 4/SIRT4

Aging (Albany, NY.), 2016-02, Vol.8 (3), p.484-505

2016

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Comparative performance analysis of human iPSC-derived and primary neural progenitor cells (NPC) grown as neurospheres in vitro

Stem cell research, 2017-12, Vol.25 (C), p.72-82

2017

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Crosstalk of clock gene expression and autophagy in aging

Aging (Albany, NY.), 2016-08, Vol.8 (9), p.1876-1895

2016

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Application of the adverse outcome pathway concept for investigating developmental neurotoxicity potential of Chinese herbal medicines by using human neural progenitor cells in vitro

Cell biology and toxicology, 2023-02, Vol.39 (1), p.319-343

2023

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Characterization and application of electrically active neuronal networks established from human induced pluripotent stem cell-derived neural progenitor cells for neurotoxicity evaluation

Stem cell research, 2020-05, Vol.45, p.101761, Article 101761

2020

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The New Aryl Hydrocarbon Receptor Antagonist E/Z-2-Benzylindene-5,6-Dimethoxy-3,3-Dimethylindan-1-One Protects against UVB-Induced Signal Transduction

Journal of investigative dermatology, 2014-02, Vol.134 (2), p.556-559

2014

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Academic application of Good Cell Culture Practice for induced pluripotent stem cells_suppl

ALTEX, alternatives to animal experimentation, 2021

Tigges, Julia

2021

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Proteome-wide analysis reveals an age-associated cellular phenotype of in situ aged human fibroblasts

Aging (Albany, NY.), 2014-11, Vol.6 (10), p.856-872

2014

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Estradiol Protects Dermal Hyaluronan/Versican Matrix during Photoaging by Release of Epidermal Growth Factor from Keratinocytes

The Journal of biological chemistry, 2012-06, Vol.287 (24), p.20056-20069

2012

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Structural chromosome abnormalities, increased DNA strand breaks and DNA strand break repair deficiency in dermal fibroblasts from old female human donors

Aging (Albany, NY.), 2015-02, Vol.7 (2), p.110-122

2015

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Activation of the aryl hydrocarbon receptor by the widely used Src family kinase inhibitor 4-amino-5-(4-chlorophenyl)-7-(dimethylethyl)pyrazolo[3,4-d]pyrimidine (PP2)

Archives of toxicology, 2015-08, Vol.89 (8), p.1329-1336

2015

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Stem Cells for Next Level Toxicity Testing in the 21st Century

Small (Weinheim an der Bergstrasse, Germany), 2021-04, Vol.17 (15), p.e2006252-n/a

2021

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The hallmarks of fibroblast ageing

Mechanisms of ageing and development, 2014-06, Vol.138, p.26-44

2014

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Environmental exposures impact the nervous system in a life stage-specific manner

Neuroforum, 2021-11, Vol.27 (4), p.201-212

2021

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The AHR represses nucleotide excision repair and apoptosis and contributes to UV-induced skin carcinogenesis

Cell death and differentiation, 2018-11, Vol.25 (10), p.1823-1836

2018

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A transcriptome comparison of time-matched developing human, mouse and rat neural progenitor cells reveals human uniqueness

Toxicology and applied pharmacology, 2018-09, Vol.354, p.40-55

2018

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Fibroblast origin shapes tissue homeostasis, epidermal differentiation, and drug uptake

Scientific reports, 2019-02, Vol.9 (1), p.2913-2913, Article 2913

2019

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Corrigendum to “Current Availability of Stem Cell-Based In Vitro Methods for Developmental Neurotoxicity (DNT) Testing”

Toxicological sciences, 2018-10, Vol.165 (2), p.531-531

2018

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Current Availability of Stem Cell-Based In Vitro Methods for Developmental Neurotoxicity (DNT) Testing

Characterization of Skin Aging–Associated Secreted Proteins (SAASP) Produced by Dermal Fibroblasts Isolated from Intrinsically Aged Human Skin

Development of the Concept for Stem Cell-Based Developmental Neurotoxicity Evaluation

The Human Induced Pluripotent Stem Cell Test as an Alternative Method for Embryotoxicity Testing

Age, gender and UV-exposition related effects on gene expression in in vivo aged short term cultivated human dermal fibroblasts

Neurodevelopmental toxicity assessment of flame retardants using a human DNT in vitro testing battery

Academic application of Good Cell Culture Practice for induced pluripotent stem cells

MicroRNA-15b regulates mitochondrial ROS production and the senescence-associated secretory phenotype through sirtuin 4/SIRT4

Comparative performance analysis of human iPSC-derived and primary neural progenitor cells (NPC) grown as neurospheres in vitro

Crosstalk of clock gene expression and autophagy in aging

Application of the adverse outcome pathway concept for investigating developmental neurotoxicity potential of Chinese herbal medicines by using human neural progenitor cells in vitro

Characterization and application of electrically active neuronal networks established from human induced pluripotent stem cell-derived neural progenitor cells for neurotoxicity evaluation

The New Aryl Hydrocarbon Receptor Antagonist E/Z-2-Benzylindene-5,6-Dimethoxy-3,3-Dimethylindan-1-One Protects against UVB-Induced Signal Transduction

Academic application of Good Cell Culture Practice for induced pluripotent stem cells_suppl

Proteome-wide analysis reveals an age-associated cellular phenotype of in situ aged human fibroblasts

Estradiol Protects Dermal Hyaluronan/Versican Matrix during Photoaging by Release of Epidermal Growth Factor from Keratinocytes

Structural chromosome abnormalities, increased DNA strand breaks and DNA strand break repair deficiency in dermal fibroblasts from old female human donors

Activation of the aryl hydrocarbon receptor by the widely used Src family kinase inhibitor 4-amino-5-(4-chlorophenyl)-7-(dimethylethyl)pyrazolo[3,4-d]pyrimidine (PP2)

Stem Cells for Next Level Toxicity Testing in the 21st Century

The hallmarks of fibroblast ageing

Environmental exposures impact the nervous system in a life stage-specific manner

The AHR represses nucleotide excision repair and apoptosis and contributes to UV-induced skin carcinogenesis

A transcriptome comparison of time-matched developing human, mouse and rat neural progenitor cells reveals human uniqueness

Fibroblast origin shapes tissue homeostasis, epidermal differentiation, and drug uptake

Corrigendum to “Current Availability of Stem Cell-Based In Vitro Methods for Developmental Neurotoxicity (DNT) Testing”

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