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Mechanisms by Which Skeletal Muscle Myokines Ameliorate Insulin Resistance

International journal of molecular sciences, 2022-04, Vol.23 (9), p.4636

2022

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Mechanisms of biphasic insulin-granule exocytosis - roles of the cytoskeleton, small GTPases and SNARE proteins

Journal of cell science, 2009-04, Vol.122 (7), p.893-903

2009

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Exocytosis proteins as novel targets for diabetes prevention and/or remediation?

American journal of physiology. Regulatory, integrative and comparative physiology, 2017-05, Vol.312 (5), p.R739-R752

2017

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A Novel Role for DOC2B in Ameliorating Palmitate-Induced Glucose Uptake Dysfunction in Skeletal Muscle Cells via a Mechanism Involving β-AR Agonism and Cofilin

International journal of molecular sciences, 2023-12, Vol.25 (1), p.137

2023

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Emerging Roles of Small GTPases in Islet β-Cell Function

Cells (Basel, Switzerland), 2021-06, Vol.10 (6), p.1503

2021

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Exocytosis Proteins: Typical and Atypical Mechanisms of Action in Skeletal Muscle

Frontiers in endocrinology (Lausanne), 2022-06, Vol.13, p.915509-915509

2022

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Promoting Glucose Transporter-4 Vesicle Trafficking along Cytoskeletal Tracks: PAK-Ing Them Out

Frontiers in endocrinology (Lausanne), 2017-11, Vol.8, p.329-329

2017

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Inhibition or Ablation of p21-activated Kinase (PAK1) Disrupts Glucose Homeostatic Mechanisms in Vivo

The Journal of biological chemistry, 2011-12, Vol.286 (48), p.41359-41367

2011

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Insulin-stimulated GLUT4 translocation requires the CAP-dependent activation of TC10

Nature (London), 2001-04, Vol.410 (6831), p.944-948

2001

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Mitochondrial Dysfunction, Oxidative Stress, and Inter-Organ Miscommunications in T2D Progression

International journal of molecular sciences, 2024-02, Vol.25 (3), p.1504

2024

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Exocytosis mechanisms underlying insulin release and glucose uptake: conserved roles for Munc18c and syntaxin 4

American journal of physiology. Regulatory, integrative and comparative physiology, 2010-03, Vol.298 (3), p.R517-R531

2010

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Glucose-stimulated Cdc42 Signaling Is Essential for the Second Phase of Insulin Secretion

The Journal of biological chemistry, 2007-03, Vol.282 (13), p.9536-9546

2007

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Doc2b serves as a scaffolding platform for concurrent binding of multiple Munc18 isoforms in pancreatic islet β-cells

Biochemical journal, 2014-12, Vol.464 (2), p.251-258

2014

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Enrichment of the exocytosis protein STX4 in skeletal muscle remediates peripheral insulin resistance and alters mitochondrial dynamics via Drp1

Nature communications, 2022-01, Vol.13 (1), p.424-424, Article 424

2022

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Differential Phosphorylation of RhoGDI Mediates the Distinct Cycling of Cdc42 and Rac1 to Regulate Second-phase Insulin Secretion

The Journal of biological chemistry, 2010-02, Vol.285 (9), p.6186-6197

2010

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Conventional and Unconventional Mechanisms by which Exocytosis Proteins Oversee β-cell Function and Protection

International journal of molecular sciences, 2021-02, Vol.22 (4), p.1833

2021

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Syntaxin 4 Overexpression Ameliorates Effects of Aging and High-Fat Diet on Glucose Control and Extends Lifespan

Cell metabolism, 2015-09, Vol.22 (3), p.499-507

2015

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Editorial: Connecting the Dots Between Obesity, Diabetes and Cancer

Frontiers in endocrinology (Lausanne), 2020-11, Vol.11, p.583456-583456

2020

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CAP defines a second signalling pathway required for insulin-stimulated glucose transport

Nature (London), 2000-09, Vol.407 (6801), p.202-207

2000

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Changes in Skeletal Muscle PAK1 Levels Regulate Tissue Crosstalk to Impact Whole Body Glucose Homeostasis

Frontiers in endocrinology (Lausanne), 2022-02, Vol.13, p.821849-821849

2022

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VAV2, a guanine nucleotide exchange factor for Rac1, regulates glucose-stimulated insulin secretion in pancreatic beta cells

Diabetologia, 2015-11, Vol.58 (11), p.2573-2581

2015

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Munc18c Depletion Selectively Impairs the Sustained Phase of Insulin Release

Diabetes (New York, N.Y.), 2009-05, Vol.58 (5), p.1165-1174

2009

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Positional cloning of a type 2 diabetes quantitative trait locus; tomosyn-2, a negative regulator of insulin secretion

PLoS genetics, 2011-10, Vol.7 (10), p.e1002323-e1002323

2011

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Filamentous Actin Regulates Insulin Exocytosis through Direct Interaction with Syntaxin 4

The Journal of biological chemistry, 2008-04, Vol.283 (16), p.10716-10726

2008

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Recent Insights into Beta-cell Exocytosis in Type 2 Diabetes

Journal of molecular biology, 2020-03, Vol.432 (5), p.1310-1325

2020

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Mechanisms by Which Skeletal Muscle Myokines Ameliorate Insulin Resistance

Mechanisms of biphasic insulin-granule exocytosis - roles of the cytoskeleton, small GTPases and SNARE proteins

Exocytosis proteins as novel targets for diabetes prevention and/or remediation?

A Novel Role for DOC2B in Ameliorating Palmitate-Induced Glucose Uptake Dysfunction in Skeletal Muscle Cells via a Mechanism Involving β-AR Agonism and Cofilin

Emerging Roles of Small GTPases in Islet β-Cell Function

Exocytosis Proteins: Typical and Atypical Mechanisms of Action in Skeletal Muscle

Promoting Glucose Transporter-4 Vesicle Trafficking along Cytoskeletal Tracks: PAK-Ing Them Out

Inhibition or Ablation of p21-activated Kinase (PAK1) Disrupts Glucose Homeostatic Mechanisms in Vivo

Insulin-stimulated GLUT4 translocation requires the CAP-dependent activation of TC10

Mitochondrial Dysfunction, Oxidative Stress, and Inter-Organ Miscommunications in T2D Progression

Exocytosis mechanisms underlying insulin release and glucose uptake: conserved roles for Munc18c and syntaxin 4

Glucose-stimulated Cdc42 Signaling Is Essential for the Second Phase of Insulin Secretion

Doc2b serves as a scaffolding platform for concurrent binding of multiple Munc18 isoforms in pancreatic islet β-cells

Enrichment of the exocytosis protein STX4 in skeletal muscle remediates peripheral insulin resistance and alters mitochondrial dynamics via Drp1

Differential Phosphorylation of RhoGDI Mediates the Distinct Cycling of Cdc42 and Rac1 to Regulate Second-phase Insulin Secretion

Conventional and Unconventional Mechanisms by which Exocytosis Proteins Oversee β-cell Function and Protection

Syntaxin 4 Overexpression Ameliorates Effects of Aging and High-Fat Diet on Glucose Control and Extends Lifespan

Editorial: Connecting the Dots Between Obesity, Diabetes and Cancer

CAP defines a second signalling pathway required for insulin-stimulated glucose transport

Changes in Skeletal Muscle PAK1 Levels Regulate Tissue Crosstalk to Impact Whole Body Glucose Homeostasis

VAV2, a guanine nucleotide exchange factor for Rac1, regulates glucose-stimulated insulin secretion in pancreatic beta cells

Munc18c Depletion Selectively Impairs the Sustained Phase of Insulin Release

Positional cloning of a type 2 diabetes quantitative trait locus; tomosyn-2, a negative regulator of insulin secretion

Filamentous Actin Regulates Insulin Exocytosis through Direct Interaction with Syntaxin 4

Recent Insights into Beta-cell Exocytosis in Type 2 Diabetes

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