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Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for CYP3A5 Genotype and Tacrolimus Dosing

Clinical pharmacology and therapeutics, 2015-07, Vol.98 (1), p.19-24

2015

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Effects of Pregnancy on CYP3A and P-glycoprotein Activities as Measured by Disposition of Midazolam and Digoxin: A University of Washington Specialized Center of Research Study

Clinical pharmacology and therapeutics, 2008-08, Vol.84 (2), p.248-253

2008

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Assessment of the Impact of Renal Impairment on Systemic Exposure of New Molecular Entities: Evaluation of Recent New Drug Applications

Clinical pharmacology and therapeutics, 2009-03, Vol.85 (3), p.305-311

2009

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Accurate Prediction of Dose‐Dependent CYP3A4 Inhibition by Itraconazole and Its Metabolites From In Vitro Inhibition Data

Clinical pharmacology and therapeutics, 2010-10, Vol.88 (4), p.499-505

2010

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Interindividual variability of CYP2C19-catalyzed drug metabolism due to differences in gene diplotypes and cytochrome P450 oxidoreductase content

The pharmacogenomics journal, 2016-08, Vol.16 (4), p.375-387

2016

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Genetic Risk Factors for Major Bleeding in Patients Treated With Warfarin in a Community Setting

Clinical pharmacology and therapeutics, 2014-06, Vol.95 (6), p.636-643

2014

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Contribution of Itraconazole Metabolites to Inhibition of CYP3A4 In Vivo

Clinical pharmacology and therapeutics, 2008-01, Vol.83 (1), p.77-85

2008

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In vitro and in vivo drug interactions involving human CYP3A

Annual review of pharmacology and toxicology, 1998-01, Vol.38 (1), p.389-430

1998

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Measurement and Compartmental Modeling of the Effect of CYP3A5 Gene Variation on Systemic and Intrarenal Tacrolimus Disposition

Clinical pharmacology and therapeutics, 2012-12, Vol.92 (6), p.737-745

2012

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Evidence of CYP3A Allosterism In Vivo: Analysis of Interaction Between Fluconazole and Midazolam

Clinical pharmacology and therapeutics, 2012-03, Vol.91 (3), p.442-449

2012

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Ethical Issues in Developing Pharmacogenetic Research Partnerships With American Indigenous Communities

Clinical pharmacology and therapeutics, 2011-03, Vol.89 (3), p.343-345

2011

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Evaluation of 6β‐Hydroxycortisol, 6β‐Hydroxycortisone, and a Combination of the Two as Endogenous Probes for Inhibition of CYP3A4 In Vivo

Clinical pharmacology and therapeutics, 2011-06, Vol.89 (6), p.888-895

2011

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Interindividual Variability in Cytochrome P450-Mediated Drug Metabolism

Drug metabolism and disposition, 2016-03, Vol.44 (3), p.343-351

2016

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Associations between diet and cardiometabolic risk among Yup'ik Alaska Native people using food frequency questionnaire dietary patterns

Nutrition, metabolism, and cardiovascular diseases, 2015-12, Vol.25 (12), p.1140-1145

2015

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Fentanyl metabolism by human hepatic and intestinal cytochrome P450 3A4: implications for interindividual variability in disposition, efficacy, and drug interactions

Drug metabolism and disposition, 1997-09, Vol.25 (9), p.1072

1997

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Reduced Duodenal Cytochrome P450 3A Protein Expression and Catalytic Activity in Patients With Cirrhosis

Clinical pharmacology and therapeutics, 2009-04, Vol.85 (4), p.387-393

2009

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Functional Comparison of Human Colonic Carcinoma Cell Lines and Primary Small Intestinal Epithelial Cells for Investigations of Intestinal Drug Permeability and First-Pass Metabolism

Drug metabolism and disposition, 2016-03, Vol.44 (3), p.329-335

2016

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Topiramate and Phenytoin Pharmacokinetics During Repetitive Monotherapy and Combination Therapy to Epileptic Patients

Epilepsia (Copenhagen), 2002-07, Vol.43 (7), p.691-696

2002

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Ethanol and production of the hepatotoxic metabolite of acetaminophen in healthy adults

Clinical pharmacology and therapeutics, 2000-06, Vol.67 (6), p.591-599

2000

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Identification of cytochrome P450 2E1 as the predominant enzyme catalyzing human liver microsomal defluorination of sevoflurane, isoflurane, and methoxyflurane

Anesthesiology (Philadelphia), 1993-10, Vol.79 (4), p.795-807

1993

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Interpatient heterogeneity in expression of CYP3A4 and CYP3A5 in small bowel. Lack of prediction by the erythromycin breath test

Drug metabolism and disposition, 1994-11, Vol.22 (6), p.947

1994

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Human kidney methoxyflurane and sevoflurane metabolism : intrarenal fluoride production as a possible mechanism of methoxyflurane nephrotoxicity

Anesthesiology (Philadelphia), 1995-03, Vol.82 (3), p.689-699

1995

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Mechanisms of enhanced oral availability of CYP3A4 substrates by grapefruit constituents. Decreased enterocyte CYP3A4 concentration and mechanism-based inactivation by furanocoumarins

Drug metabolism and disposition, 1997-11, Vol.25 (11), p.1228

1997

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First-pass metabolism of midazolam by the human intestine

Clinical pharmacology and therapeutics, 1996-07, Vol.60 (1), p.14-24

1996

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Immunoquantitation of FMO1 in human liver, kidney, and intestine

Drug metabolism and disposition, 2000-09, Vol.28 (9), p.1107

2000

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Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for CYP3A5 Genotype and Tacrolimus Dosing

Effects of Pregnancy on CYP3A and P-glycoprotein Activities as Measured by Disposition of Midazolam and Digoxin: A University of Washington Specialized Center of Research Study

Assessment of the Impact of Renal Impairment on Systemic Exposure of New Molecular Entities: Evaluation of Recent New Drug Applications

Accurate Prediction of Dose‐Dependent CYP3A4 Inhibition by Itraconazole and Its Metabolites From In Vitro Inhibition Data

Interindividual variability of CYP2C19-catalyzed drug metabolism due to differences in gene diplotypes and cytochrome P450 oxidoreductase content

Genetic Risk Factors for Major Bleeding in Patients Treated With Warfarin in a Community Setting

Contribution of Itraconazole Metabolites to Inhibition of CYP3A4 In Vivo

In vitro and in vivo drug interactions involving human CYP3A

Measurement and Compartmental Modeling of the Effect of CYP3A5 Gene Variation on Systemic and Intrarenal Tacrolimus Disposition

Evidence of CYP3A Allosterism In Vivo: Analysis of Interaction Between Fluconazole and Midazolam

Ethical Issues in Developing Pharmacogenetic Research Partnerships With American Indigenous Communities

Evaluation of 6β‐Hydroxycortisol, 6β‐Hydroxycortisone, and a Combination of the Two as Endogenous Probes for Inhibition of CYP3A4 In Vivo

Interindividual Variability in Cytochrome P450-Mediated Drug Metabolism

Associations between diet and cardiometabolic risk among Yup'ik Alaska Native people using food frequency questionnaire dietary patterns

Fentanyl metabolism by human hepatic and intestinal cytochrome P450 3A4: implications for interindividual variability in disposition, efficacy, and drug interactions

Reduced Duodenal Cytochrome P450 3A Protein Expression and Catalytic Activity in Patients With Cirrhosis

Functional Comparison of Human Colonic Carcinoma Cell Lines and Primary Small Intestinal Epithelial Cells for Investigations of Intestinal Drug Permeability and First-Pass Metabolism

Topiramate and Phenytoin Pharmacokinetics During Repetitive Monotherapy and Combination Therapy to Epileptic Patients

Ethanol and production of the hepatotoxic metabolite of acetaminophen in healthy adults

Identification of cytochrome P450 2E1 as the predominant enzyme catalyzing human liver microsomal defluorination of sevoflurane, isoflurane, and methoxyflurane

Interpatient heterogeneity in expression of CYP3A4 and CYP3A5 in small bowel. Lack of prediction by the erythromycin breath test

Human kidney methoxyflurane and sevoflurane metabolism : intrarenal fluoride production as a possible mechanism of methoxyflurane nephrotoxicity

Mechanisms of enhanced oral availability of CYP3A4 substrates by grapefruit constituents. Decreased enterocyte CYP3A4 concentration and mechanism-based inactivation by furanocoumarins

First-pass metabolism of midazolam by the human intestine

Immunoquantitation of FMO1 in human liver, kidney, and intestine

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