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Alternative Complement Pathway Inhibition Does Not Abrogate Meningococcal Killing by Serum of Vaccinated Individuals

Frontiers in immunology, 2021-10, Vol.12, p.747594-747594

2021

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Alternative Complement Pathway Inhibition Abrogates Pneumococcal Opsonophagocytosis in Vaccine-Naïve, but Not in Vaccinated Individuals

Frontiers in immunology, 2021-10, Vol.12, p.732146-732146

2021

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Inhibition of the different complement pathways has varying impacts on the serum bactericidal activity and opsonophagocytosis against Haemophilus influenzae type b

Frontiers in immunology, 2022-12, Vol.13, p.1020580-1020580

2022

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Gastrin and colorectal cancer: A prospective study

Gastroenterology (New York, N.Y. 1943), 1998-08, Vol.115 (2), p.275-280

1998

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Clinical Breakthrough Hemolysis (BTH) during Monotherapy with the Oral Factor B Inhibitor Iptacopan Is Generally Not Severe and Managed without Treatment Discontinuation: 48-Week Data from the Phase III Apply-PNH and Appoint-PNH Trials in Paroxysmal Nocturnal Hemoglobinuria (PNH)

Blood, 2023-11, Vol.142 (Supplement 1), p.1338-1338

2023

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Choosing wisely: The American College of Rheumatology's top 5 list of things physicians and patients should question

Arthritis care & research (2010), 2013-03, Vol.65 (3), p.329-339

2013

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Oral Monotherapy with Iptacopan, a Proximal Complement Inhibitor of Factor B, Has Superior Efficacy to Intravenous Terminal Complement Inhibition with Standard of Care Eculizumab or Ravulizumab and Favorable Safety in Patients with Paroxysmal Nocturnal Hemoglobinuria and Residual Anemia: Results from the Randomized, Active-Comparator-Controlled, Open-Label, Multicenter, Phase III Apply-PNH Study

Blood, 2022-12, Vol.140 (Supplement 2), p.LBA-2-LBA-2

2022

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Oral Monotherapy with Iptacopan, a Proximal Complement Inhibitor of Factor B, Has Superior Efficacy to Intravenous Terminal Complement Inhibition with Standard of Care Eculizumab or Ravulizumab and Favorable Safety in Patients with Paroxysmal Nocturnal Hemoglobinuria and Residual Anemia: Results from the Randomized, Active-Comparator-Controlled, Open-Label, Multicenter, Phase III Apply-PNH Study

Blood, 2022-12, Vol.140, p.5-9

2022

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A randomized, blinded, parallel group, placebo controlled pilot study evaluating the effect of PVAC treatment in patients with diffuse systemic sclerosis

Journal of rheumatology, 2005-12, Vol.32 (12), p.2345

2005

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Factor B Inhibition with Oral Iptacopan Monotherapy Demonstrates Sustained Long-Term Efficacy and Safety in Anti-C5-Treated Patients (pts) with Paroxysmal Nocturnal Hemoglobinuria (PNH) and Persistent Anemia: Final 48-Week Results from the Multicenter, Phase III APPLY-PNH Trial

Blood, 2023-11, Vol.142 (Supplement 1), p.571-571

2023

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The effect of pharmacokinetics on the bactericidal activity of ciprofloxacin and sparfloxacin against Streptococcus pneumoniae and the emergence of resistance

Journal of antimicrobial chemotherapy, 2001-07, Vol.48 (1), p.15-22

2001

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In Vitro Activities of Oral β-Lactams at Concentrations Achieved in Humans against Penicillin-Susceptible and -Resistant Pneumococci and Potential to Select Resistance

Antimicrobial Agents and Chemotherapy, 1998-08, Vol.42 (8), p.1973-1979

1998

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POSTER: MDS-278 Substantial Increases in Paroxysmal Nocturnal Hemoglobinuria (PNH) Red Blood Cell Clone Size With Oral Iptacopan Monotherapy Confirms Control of Hemolysis in Complement Inhibitor-Naive PNH Patients

Clinical lymphoma, myeloma and leukemia, 2023-09, Vol.23, p.S185-S185

2023

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MDS-278 Substantial Increases in Paroxysmal Nocturnal Hemoglobinuria (PNH) Red Blood Cell Clone Size With Oral Iptacopan Monotherapy Confirms Control of Hemolysis in Complement Inhibitor-Naive PNH Patients

Clinical lymphoma, myeloma and leukemia, 2023-09, Vol.23, p.S361-S361

2023

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183 - Comparison of Angioedema in Heart Failure Patients Treated with Sacubitril/Valsartan or Enalapril in the PARADIGM-HF Study

Journal of cardiac failure, 2016-08, Vol.22 (8), p.S66-S67

2016

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POSTER: MDS-273 Oral Iptacopan Monotherapy Increases Paroxysmal Nocturnal Hemoglobinuria (PNH) Red Blood Cell Clone Size Via Control of Intra- and Extravascular Hemolysis in Anti-C5-Treated PNH Patients With Anemia

Clinical lymphoma, myeloma and leukemia, 2023-09, Vol.23, p.S185-S185

2023

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MDS-273 Oral Iptacopan Monotherapy Increases Paroxysmal Nocturnal Hemoglobinuria (PNH) Red Blood Cell Clone Size Via Control of Intra- and Extravascular Hemolysis in Anti-C5-Treated PNH Patients With Anemia

Clinical lymphoma, myeloma and leukemia, 2023-09, Vol.23, p.S360-S360

2023

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S182: ORAL IPTACOPAN MONOTHERAPY INCREASES PAROXYSMAL NOCTURNAL HEMOGLOBINURIA (PNH) RED BLOOD CELL CLONE SIZE VIA CONTROL OF INTRA‐ AND EXTRAVASCULAR HEMOLYSIS IN ANTI‐C5‐TREATED PNH PATIENTS WITH ANEMIA

HemaSphere, 2023-08, Vol.7 (S3), p.e29006c9-n/a

2023

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Bacteriological Efficacies of Three Macrolides Compared with Those of Amoxicillin-Clavulanate againstStreptococcus pneumoniae and Haemophilus influenzae

Antimicrobial Agents and Chemotherapy, 1998-12, Vol.42 (12), p.3193-3199

1998

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Hospitalizations for coronary artery disease among patients with systemic lupus erythematosus

Arthritis and rheumatism, 2003-09, Vol.48 (9), p.2519-2523

2003

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Postantibiotic and post-beta-lactamase inhibitor effects of amoxicillin plus clavulanate

Antimicrobial Agents and Chemotherapy, 1996-12, Vol.40 (12), p.2796-2801

1996

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Bacteriological efficacies of three macrolides compared with those of amoxicillin-clavulanate against Streptococcus pneumoniae and Haemophilus influenzae

Antimicrobial agents and chemotherapy, 1998-12, Vol.42 (12), p.3193-3199

1998

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Interaction between RNA-Dependent RNA Polymerase of Alfalfa Mosaic Virus and Its Template: Oxidation of Vicinal Hydroxyl Groups Blocksin VitroRNA Synthesis

Virology (New York, N.Y.), 1995-11, Vol.213 (2), p.650-654

1995

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Epidemiology of Gastric Non-Hodgkin's Lymphoma Patients: Parallels with Helicobacter pylori

Helicobacter (Cambridge, Mass.), 1996-06, Vol.1 (2), p.75-78

1996

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Alternative Complement Pathway Inhibition Does Not Abrogate Meningococcal Killing by Serum of Vaccinated Individuals

Alternative Complement Pathway Inhibition Abrogates Pneumococcal Opsonophagocytosis in Vaccine-Naïve, but Not in Vaccinated Individuals

Inhibition of the different complement pathways has varying impacts on the serum bactericidal activity and opsonophagocytosis against Haemophilus influenzae type b

P774: SUBSTANTIAL INCREASES IN PAROXYSMAL NOCTURNAL HEMOGLOBINURIA (PNH) RED BLOOD CELL CLONE SIZE WITH ORAL IPTACOPAN MONOTHERAPY CONFIRMS CONTROL OF HEMOLYSIS IN COMPLEMENT INHIBITOR‐NAÏVE PNH PATIENTS

Gastrin and colorectal cancer: A prospective study

Clinical Breakthrough Hemolysis (BTH) during Monotherapy with the Oral Factor B Inhibitor Iptacopan Is Generally Not Severe and Managed without Treatment Discontinuation: 48-Week Data from the Phase III Apply-PNH and Appoint-PNH Trials in Paroxysmal Nocturnal Hemoglobinuria (PNH)

Choosing wisely: The American College of Rheumatology's top 5 list of things physicians and patients should question

A randomized, blinded, parallel group, placebo controlled pilot study evaluating the effect of PVAC treatment in patients with diffuse systemic sclerosis

Factor B Inhibition with Oral Iptacopan Monotherapy Demonstrates Sustained Long-Term Efficacy and Safety in Anti-C5-Treated Patients (pts) with Paroxysmal Nocturnal Hemoglobinuria (PNH) and Persistent Anemia: Final 48-Week Results from the Multicenter, Phase III APPLY-PNH Trial

The effect of pharmacokinetics on the bactericidal activity of ciprofloxacin and sparfloxacin against Streptococcus pneumoniae and the emergence of resistance

In Vitro Activities of Oral β-Lactams at Concentrations Achieved in Humans against Penicillin-Susceptible and -Resistant Pneumococci and Potential to Select Resistance

POSTER: MDS-278 Substantial Increases in Paroxysmal Nocturnal Hemoglobinuria (PNH) Red Blood Cell Clone Size With Oral Iptacopan Monotherapy Confirms Control of Hemolysis in Complement Inhibitor-Naive PNH Patients

MDS-278 Substantial Increases in Paroxysmal Nocturnal Hemoglobinuria (PNH) Red Blood Cell Clone Size With Oral Iptacopan Monotherapy Confirms Control of Hemolysis in Complement Inhibitor-Naive PNH Patients

183 - Comparison of Angioedema in Heart Failure Patients Treated with Sacubitril/Valsartan or Enalapril in the PARADIGM-HF Study

POSTER: MDS-273 Oral Iptacopan Monotherapy Increases Paroxysmal Nocturnal Hemoglobinuria (PNH) Red Blood Cell Clone Size Via Control of Intra- and Extravascular Hemolysis in Anti-C5-Treated PNH Patients With Anemia

MDS-273 Oral Iptacopan Monotherapy Increases Paroxysmal Nocturnal Hemoglobinuria (PNH) Red Blood Cell Clone Size Via Control of Intra- and Extravascular Hemolysis in Anti-C5-Treated PNH Patients With Anemia

S182: ORAL IPTACOPAN MONOTHERAPY INCREASES PAROXYSMAL NOCTURNAL HEMOGLOBINURIA (PNH) RED BLOOD CELL CLONE SIZE VIA CONTROL OF INTRA‐ AND EXTRAVASCULAR HEMOLYSIS IN ANTI‐C5‐TREATED PNH PATIENTS WITH ANEMIA

Bacteriological Efficacies of Three Macrolides Compared with Those of Amoxicillin-Clavulanate againstStreptococcus pneumoniae and Haemophilus influenzae

Hospitalizations for coronary artery disease among patients with systemic lupus erythematosus

Postantibiotic and post-beta-lactamase inhibitor effects of amoxicillin plus clavulanate

Bacteriological efficacies of three macrolides compared with those of amoxicillin-clavulanate against Streptococcus pneumoniae and Haemophilus influenzae

Interaction between RNA-Dependent RNA Polymerase of Alfalfa Mosaic Virus and Its Template: Oxidation of Vicinal Hydroxyl Groups Blocksin VitroRNA Synthesis

Epidemiology of Gastric Non-Hodgkin's Lymphoma Patients: Parallels with Helicobacter pylori

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