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Phosphate steering by Flap Endonuclease 1 promotes 5'-flap specificity and incision to prevent genome instability

Nature communications, 2017-06, Vol.8 (1), p.15855-15855, Article 15855

2017

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Cellularly active N-hydroxyurea FEN1 inhibitors block substrate entry to the active site

Nature chemical biology, 2016-10, Vol.12 (10), p.815-821

2016

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Exploring Catalyst and Solvent Effects in the Multicomponent Synthesis of Pyridine-3,5-dicarbonitriles

Journal of organic chemistry, 2009-09, Vol.74 (18), p.6999-7006

2009

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Synthesis of Polyanionic C5-Modified 2'-Deoxyuridine and 2'-Deoxycytidine-5'-Triphosphates and Their Properties as Substrates for DNA Polymerases

Molecules (Basel, Switzerland), 2021-04, Vol.26 (8), p.2250

2021

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Design, Synthesis, and Structure−Activity Relationship of Indole-3-glyoxylamide Libraries Possessing Highly Potent Activity in a Cell Line Model of Prion Disease

Journal of medicinal chemistry, 2009-12, Vol.52 (23), p.7503-7511

2009

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Synthesis and evaluation of a focused library of pyridine dicarbonitriles against prion disease

European journal of medicinal chemistry, 2008, Vol.43 (1), p.93-106

2008

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The Storytelling Aspect of Interpersonal Relations: Understanding "Relating" from a Mentalization Point of View

Psychodynamic psychiatry, 2016-09, Vol.44 (3), p.423-448

2016

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Catalytic Roles for Carbon-Oxygen Hydrogen Bonding in SET Domain Lysine Methyltransferases

The Journal of biological chemistry, 2006-07, Vol.281 (28), p.19280-19287

2006

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Reduced intra‐subject variability of an automated skin prick test device compared to a manual test

Allergy (Copenhagen), 2023-05, Vol.78 (5), p.1366-1368

2023

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Ugi Reactions with Ammonia Offer Rapid Access to a Wide Range of 5-Aminothiazole and Oxazole Derivatives

Journal of organic chemistry, 2009-09, Vol.74 (18), p.7084-7093

2009

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Library Synthesis and Screening: 2,4-Diphenylthiazoles and 2,4-Diphenyloxazoles as Potential Novel Prion Disease Therapeutics

Journal of medicinal chemistry, 2007-03, Vol.50 (6), p.1347-1353

2007

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Improved 2,4-Diarylthiazole-Based Antiprion Agents: Switching the Sense of the Amide Group at C5 Leads to an Increase in Potency

ChemMedChem, 2010-09, Vol.5 (9), p.1476-1488

2010

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Chemical Tools for Studying Phosphohistidine: Generation of Selective τ‐Phosphohistidine and π‐Phosphohistidine Antibodies

Chembiochem : a European journal of chemical biology, 2023-08, Vol.24 (16), p.e202300182-n/a

2023

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A conserved loop-wedge motif moderates reaction site search and recognition by FEN1

Nucleic acids research, 2018-09, Vol.46 (15), p.7858-7872

2018

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Relationships between In Situ and Roller-Integrated Compaction Measurements for Granular Soils

Journal of geotechnical and geoenvironmental engineering, 2008-12, Vol.134 (12), p.1763-1770

2008

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The Stories We Tell Ourselves: Mentalizing Tales of Dating and Marriage

1, 2014

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4-Phosphopyrazol-2-yl alanine: a non-hydrolysable analogue of phosphohistidine

Chemical communications (Cambridge, England), 2015-04, Vol.51 (34), p.7305-7308

2015

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An Orally Bioavailable, Indole-3-glyoxylamide Based Series of Tubulin Polymerization Inhibitors Showing Tumor Growth Inhibition in a Mouse Xenograft Model of Head and Neck Cancer

Journal of medicinal chemistry, 2015-12, Vol.58 (23), p.9309-9333

2015

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Regional conformational flexibility couples substrate specificity and scissile phosphate diester selectivity in human flap endonuclease 1

Nucleic acids research, 2018-06, Vol.46 (11), p.5618-5633

2018

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DNA and Protein Requirements for Substrate Conformational Changes Necessary for Human Flap Endonuclease-1-catalyzed Reaction

The Journal of biological chemistry, 2016-04, Vol.291 (15), p.8258-8268

2016

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Estimating Compaction of Cohesive Soils from Machine Drive Power

Journal of geotechnical and geoenvironmental engineering, 2008-12, Vol.134 (12), p.1771-1777

2008

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Regioselective Synthesis of 3‑Aminoimidazo[1,2‑a]‑pyrimidines under Continuous Flow Conditions

Journal of organic chemistry, 2014-11, Vol.79 (21), p.10196-10202

2014

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A Small Molecule Modulator of Prion Protein Increases Human Mesenchymal Stem Cell Lifespan, Ex Vivo Expansion, and Engraftment to Bone Marrow in NOD/SCID Mice

Stem cells (Dayton, Ohio), 2012-06, Vol.30 (6), p.1134-1143

2012

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Development of a Diversity-Oriented Approach to Oxazole-5-amide Libraries

Journal of organic chemistry, 2009-05, Vol.74 (10), p.3856-3865

2009

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Corrigendum: Phosphate steering by Flap Endonuclease 1 promotes 5'-flap specificity and incision to prevent genome instability

Nature communications, 2017, Vol.8, p.16145-16145

2017

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Phosphate steering by Flap Endonuclease 1 promotes 5'-flap specificity and incision to prevent genome instability

Cellularly active N-hydroxyurea FEN1 inhibitors block substrate entry to the active site

Exploring Catalyst and Solvent Effects in the Multicomponent Synthesis of Pyridine-3,5-dicarbonitriles

Synthesis of Polyanionic C5-Modified 2'-Deoxyuridine and 2'-Deoxycytidine-5'-Triphosphates and Their Properties as Substrates for DNA Polymerases

Design, Synthesis, and Structure−Activity Relationship of Indole-3-glyoxylamide Libraries Possessing Highly Potent Activity in a Cell Line Model of Prion Disease

Synthesis and evaluation of a focused library of pyridine dicarbonitriles against prion disease

The Storytelling Aspect of Interpersonal Relations: Understanding "Relating" from a Mentalization Point of View

Catalytic Roles for Carbon-Oxygen Hydrogen Bonding in SET Domain Lysine Methyltransferases

Reduced intra‐subject variability of an automated skin prick test device compared to a manual test

Ugi Reactions with Ammonia Offer Rapid Access to a Wide Range of 5-Aminothiazole and Oxazole Derivatives

Library Synthesis and Screening: 2,4-Diphenylthiazoles and 2,4-Diphenyloxazoles as Potential Novel Prion Disease Therapeutics

Improved 2,4-Diarylthiazole-Based Antiprion Agents: Switching the Sense of the Amide Group at C5 Leads to an Increase in Potency

Chemical Tools for Studying Phosphohistidine: Generation of Selective τ‐Phosphohistidine and π‐Phosphohistidine Antibodies

A conserved loop-wedge motif moderates reaction site search and recognition by FEN1

Relationships between In Situ and Roller-Integrated Compaction Measurements for Granular Soils

The Stories We Tell Ourselves: Mentalizing Tales of Dating and Marriage

4-Phosphopyrazol-2-yl alanine: a non-hydrolysable analogue of phosphohistidine

An Orally Bioavailable, Indole-3-glyoxylamide Based Series of Tubulin Polymerization Inhibitors Showing Tumor Growth Inhibition in a Mouse Xenograft Model of Head and Neck Cancer

Regional conformational flexibility couples substrate specificity and scissile phosphate diester selectivity in human flap endonuclease 1

DNA and Protein Requirements for Substrate Conformational Changes Necessary for Human Flap Endonuclease-1-catalyzed Reaction

Estimating Compaction of Cohesive Soils from Machine Drive Power

Regioselective Synthesis of 3‑Aminoimidazo[1,2‑a]‑pyrimidines under Continuous Flow Conditions

A Small Molecule Modulator of Prion Protein Increases Human Mesenchymal Stem Cell Lifespan, Ex Vivo Expansion, and Engraftment to Bone Marrow in NOD/SCID Mice

Development of a Diversity-Oriented Approach to Oxazole-5-amide Libraries

Corrigendum: Phosphate steering by Flap Endonuclease 1 promotes 5'-flap specificity and incision to prevent genome instability

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