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Inhibiting autophagy reduces retinal degeneration caused by protein misfolding

Autophagy, 2018-07, Vol.14 (7), p.1226-1238

2018

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Relative Contributions of All-Trans and 11-Cis Retinal to Formation of Lipofuscin and A2E Accumulating in Mouse Retinal Pigment Epithelium

Investigative ophthalmology & visual science, 2021-02, Vol.62 (2), p.1-1

2021

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Reduction of All-trans-retinal in Vertebrate Rod Photoreceptors Requires the Combined Action of RDH8 and RDH12

The Journal of biological chemistry, 2012-07, Vol.287 (29), p.24662-24670

2012

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Shifting the balance of autophagy and proteasome activation reduces proteotoxic cell death: a novel therapeutic approach for restoring photoreceptor homeostasis

Cell death & disease, 2019-07, Vol.10 (8), p.547-14, Article 547

2019

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Oxidative stress differentially impacts apical and basolateral secretion of angiogenic factors from human iPSC-derived retinal pigment epithelium cells

Scientific reports, 2022-07, Vol.12 (1), p.12694-13, Article 12694

2022

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Association of Geroprotective Effects of Metformin and Risk of Open-Angle Glaucoma in Persons With Diabetes Mellitus

JAMA ophthalmology, 2015-08, Vol.133 (8), p.915

2015

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Pharmacologic activation of autophagy without direct mTOR inhibition as a therapeutic strategy for treating dry macular degeneration

Aging (Albany, NY.), 2021-04, Vol.13 (8), p.10866-10890

2021

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Mobile app use to support therapeutic exercise for musculoskeletal pain conditions may help improve pain intensity and self-reported physical function: a systematic review

Journal of physiotherapy, 2023-01, Vol.69 (1), p.23-34

2023

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Interphotoreceptor retinoid–binding protein removes all-trans-retinol and retinal from rod outer segments, preventing lipofuscin precursor formation

The Journal of biological chemistry, 2017-11, Vol.292 (47), p.19356-19365

2017

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Rd9 is a naturally occurring mouse model of a common form of retinitis pigmentosa caused by mutations in RPGR-ORF15

PloS one, 2012-05, Vol.7 (5), p.e35865-e35865

2012

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MERTK interactions with SH2-domain proteins in the retinal pigment epithelium

PloS one, 2013-02, Vol.8 (2), p.e53964-e53964

2013

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Autosomal-Recessive Posterior Microphthalmos Is Caused by Mutations in PRSS56, a Gene Encoding a Trypsin-Like Serine Protease

American journal of human genetics, 2011-03, Vol.88 (3), p.382-390

2011

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Circadian and noncircadian modulation of autophagy in photoreceptors and retinal pigment epithelium

Investigative ophthalmology & visual science, 2014-04, Vol.55 (5), p.3237-3246

2014

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Natural History and Genotype-Phenotype Correlations in RDH12-Associated Retinal Degeneration

Advances in experimental medicine and biology, 2019, Vol.1185, p.209-213

2019

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Deletion of autophagy inducer RB1CC1 results in degeneration of the retinal pigment epithelium

Autophagy, 2015-01, Vol.11 (6), p.939-953

2015

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Detailed clinical characterisation, unique features and natural history of autosomal recessive RDH12 -associated retinal degeneration

British journal of ophthalmology, 2019-12, Vol.103 (12), p.1789

2019

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Highly Differentiated Human Fetal RPE Cultures Are Resistant to the Accumulation and Toxicity of Lipofuscin-Like Material

Investigative ophthalmology & visual science, 2019-08, Vol.60 (10), p.3468-3479

2019

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Vitamin A metabolism in the retinal pigment epithelium: genes, mutations, and diseases

Progress in retinal and eye research, 2003-09, Vol.22 (5), p.683-703

2003

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Advancing therapeutic strategies for inherited retinal degeneration: recommendations from the Monaciano Symposium

Investigative ophthalmology & visual science, 2015-02, Vol.56 (2), p.918-931

2015

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Development of a Gene Therapy Vector for RDH12 -Associated Retinal Dystrophy

Human gene therapy, 2019-11, Vol.30 (11), p.1325

2019

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Mutations in MERTK , the human orthologue of the RCS rat retinal dystrophy gene, cause retinitis pigmentosa

Nature genetics, 2000-11, Vol.26 (3), p.270-271

2000

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A platform for assessing outer segment fate in primary human fetal RPE cultures

Experimental eye research, 2019-01, Vol.178, p.212-222

2019

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Reduced Retinal Pigment Epithelial Autophagy Due to Loss of Rab12 Prenylation in a Human iPSC-RPE Model of Choroideremia

Cells (Basel, Switzerland), 2024-06, Vol.13 (12), p.1068

2024

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The Politics of the Census: Lessons from Abroad

Canadian public policy, 2010-09, Vol.36 (3), p.377-382

Thompson, Debra

2010

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An Exoneration of Black Rage

The South Atlantic quarterly, 2017-07, Vol.116 (3), p.457

Thompson, Debra

2017

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Inhibiting autophagy reduces retinal degeneration caused by protein misfolding

Relative Contributions of All-Trans and 11-Cis Retinal to Formation of Lipofuscin and A2E Accumulating in Mouse Retinal Pigment Epithelium

Reduction of All-trans-retinal in Vertebrate Rod Photoreceptors Requires the Combined Action of RDH8 and RDH12

Shifting the balance of autophagy and proteasome activation reduces proteotoxic cell death: a novel therapeutic approach for restoring photoreceptor homeostasis

Oxidative stress differentially impacts apical and basolateral secretion of angiogenic factors from human iPSC-derived retinal pigment epithelium cells

Association of Geroprotective Effects of Metformin and Risk of Open-Angle Glaucoma in Persons With Diabetes Mellitus

Pharmacologic activation of autophagy without direct mTOR inhibition as a therapeutic strategy for treating dry macular degeneration

Mobile app use to support therapeutic exercise for musculoskeletal pain conditions may help improve pain intensity and self-reported physical function: a systematic review

Interphotoreceptor retinoid–binding protein removes all-trans-retinol and retinal from rod outer segments, preventing lipofuscin precursor formation

Rd9 is a naturally occurring mouse model of a common form of retinitis pigmentosa caused by mutations in RPGR-ORF15

MERTK interactions with SH2-domain proteins in the retinal pigment epithelium

Autosomal-Recessive Posterior Microphthalmos Is Caused by Mutations in PRSS56, a Gene Encoding a Trypsin-Like Serine Protease

Circadian and noncircadian modulation of autophagy in photoreceptors and retinal pigment epithelium

Natural History and Genotype-Phenotype Correlations in RDH12-Associated Retinal Degeneration

Deletion of autophagy inducer RB1CC1 results in degeneration of the retinal pigment epithelium

Detailed clinical characterisation, unique features and natural history of autosomal recessive RDH12 -associated retinal degeneration

Highly Differentiated Human Fetal RPE Cultures Are Resistant to the Accumulation and Toxicity of Lipofuscin-Like Material

Vitamin A metabolism in the retinal pigment epithelium: genes, mutations, and diseases

Advancing therapeutic strategies for inherited retinal degeneration: recommendations from the Monaciano Symposium

Development of a Gene Therapy Vector for RDH12 -Associated Retinal Dystrophy

Mutations in MERTK , the human orthologue of the RCS rat retinal dystrophy gene, cause retinitis pigmentosa

A platform for assessing outer segment fate in primary human fetal RPE cultures

Reduced Retinal Pigment Epithelial Autophagy Due to Loss of Rab12 Prenylation in a Human iPSC-RPE Model of Choroideremia

The Politics of the Census: Lessons from Abroad

An Exoneration of Black Rage

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