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Using Artificial Intelligence to Detect, Classify, and Objectively Score Severity of Rodent Cardiomyopathy

Toxicologic pathology, 2021-06, Vol.49 (4), p.888-896

2021

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Protein Extraction of Formalin-fixed, Paraffin-embedded Tissue Enables Robust Proteomic Profiles by Mass Spectrometry

The journal of histochemistry and cytochemistry, 2009-09, Vol.57 (9), p.849-860

2009

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Spontaneous Findings in the Heart of Mauritian-Origin Cynomolgus Macaques (Macaca fascicularis)

Toxicologic pathology, 2010-02, Vol.38 (2), p.297-302

2010

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Inter-Rater and Intra-Rater Agreement in Scoring Severity of Rodent Cardiomyopathy and Relation to Artificial Intelligence–Based Scoring

Toxicologic pathology, 2024-07, Vol.52 (5), p.258-265

2024

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Scientific and Regulatory Policy Committee Points to Consider: Review of the United States Food and Drug Administration (FDA) Guidance on Pathology Peer Review in Nonclinical Toxicology Studies

Toxicologic pathology, 2024-02, Vol.52 (2-3), p.138-148

2024

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Evaluation of the Cynomolgus Monkey Stomach: Recommendations for Standard Sampling Procedures in Nonclinical Safety Studies

Toxicologic pathology, 2008-02, Vol.36 (2), p.250-255

2008

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Effects of 6-hydroxydopamine on mitochondrial function and glutathione status in SH-SY5Y human neuroblastoma cells

Toxicology in vitro, 2005-06, Vol.19 (4), p.471-479

2005

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Role of p38 in regulation of hematopoiesis: Effect of p38 inhibition on cytokine production and transcription factor activity in human bone marrow stromal cells

Blood cells, molecules, & diseases, 2008-05, Vol.40 (3), p.370-380

2008

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MicroRNA changes in rat mesentery and serum associated with drug-induced vascular injury

Toxicology and applied pharmacology, 2012-08, Vol.262 (3), p.310-320

2012

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Potential candidate genomic biomarkers of drug induced vascular injury in the rat

Toxicology and applied pharmacology, 2011-12, Vol.257 (2), p.284-300

2011

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SB 239063, a potent p38 MAP kinase inhibitor, reduces inflammatory cytokine production, airways eosinophil infiltration, and persistence

The Journal of pharmacology and experimental therapeutics, 2000-04, Vol.293 (1), p.281

2000

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Effects of Troglitazone on HepG2 Viability and Mitochondrial Function

Toxicological sciences, 2002-09, Vol.69 (1), p.131-138

2002

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Detection and characterization of circulating endothelial progenitor cells in normal rat blood

Journal of pharmacological and toxicological methods, 2009-11, Vol.60 (3), p.263-274

2009

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Transcriptional Profiling of Laser Capture Microdissected Rat Arterial Elements: Fenoldopam-induced Vascular Toxicity as a Model System

Toxicologic pathology, 2008-04, Vol.36 (3), p.496-519

2008

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Industry Survey of Approaches to Examination and Terminology of Spontaneous Changes in the Heart of Young Rats

Toxicologic pathology, 2010-10, Vol.38 (6), p.995-998

2010

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Etomoxir-Induced Oxidative Stress in HepG2 Cells Detected by Differential Gene Expression Is Confirmed Biochemically

Toxicological sciences, 2002-07, Vol.68 (1), p.93-101

2002

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Staurosporine-induced Apoptosis in Cardiomyocytes: A Potential Role of Caspase-3

Journal of molecular and cellular cardiology, 1998-03, Vol.30 (3), p.495-507

1998

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Response to Nyska and Gruebbel

Toxicologic pathology, 2010-04, Vol.38 (3), p.513-513

2010

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Confounding effects of platelets on flow cytometric analysis and cell‐sorting experiments using blood‐derived cells

Cytometry. Part A, 2006-02, Vol.69A (2), p.86-94

2006

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Correlative Confocal and Light Microscopic Analysis of Rat Scalp Skin

Microscopy and microanalysis, 2003-08, Vol.9 (S02), p.1252-1253

2003

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Prolonged Cell-cycle Arrest Associated with Altered cdc2 Kinase in Monocrotaline Pyrrole-treated Pulmonary Artery Endothelial Cells

American journal of respiratory cell and molecular biology, 1998-07, Vol.19 (1), p.129-142

1998

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Differences in pathogenicity of herpes simplex virus serotypes 1 and 2 may be observed by histopathology and high-resolution magnetic resonance imaging in a murine encephalitis model

Journal of neurovirology, 2001-04, Vol.7 (2), p.105-116

Heath C Thomas, Rasesh D Kapadia, Grace I Wells, Andrew M Gresham, David Sutton, Henk A Solleveld, Susanta K Sarkar, Susan B Dillon, Ruth Tal-Singer

2001

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Immunolocalization Of Phosphodiesterase Isoenzymes In Rat Tissues Using Confocal Microscopy

Microscopy and microanalysis, 2002-08, Vol.8 (S02), p.138-139

2002

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Using Artificial Intelligence to Detect, Classify, and Objectively Score Severity of Rodent Cardiomyopathy

Protein Extraction of Formalin-fixed, Paraffin-embedded Tissue Enables Robust Proteomic Profiles by Mass Spectrometry

Spontaneous Findings in the Heart of Mauritian-Origin Cynomolgus Macaques (Macaca fascicularis)

Inter-Rater and Intra-Rater Agreement in Scoring Severity of Rodent Cardiomyopathy and Relation to Artificial Intelligence–Based Scoring

Scientific and Regulatory Policy Committee Points to Consider: Review of the United States Food and Drug Administration (FDA) Guidance on Pathology Peer Review in Nonclinical Toxicology Studies

Evaluation of the Cynomolgus Monkey Stomach: Recommendations for Standard Sampling Procedures in Nonclinical Safety Studies

Effects of 6-hydroxydopamine on mitochondrial function and glutathione status in SH-SY5Y human neuroblastoma cells

Role of p38 in regulation of hematopoiesis: Effect of p38 inhibition on cytokine production and transcription factor activity in human bone marrow stromal cells

MicroRNA changes in rat mesentery and serum associated with drug-induced vascular injury

A Diagnostic Approach for Rodent Progressive Cardiomyopathy and Like Lesions in Toxicology Studies up to 28 Days in the Sprague Dawley Rat (Part 1 of 2)

A Diagnostic Approach for Rodent Progressive Cardiomyopathy and Like Lesions in Toxicology Studies up to 28 Days in the Sprague Dawley Rat (Part 2 of 2)

Potential candidate genomic biomarkers of drug induced vascular injury in the rat

SB 239063, a potent p38 MAP kinase inhibitor, reduces inflammatory cytokine production, airways eosinophil infiltration, and persistence

Effects of Troglitazone on HepG2 Viability and Mitochondrial Function

Detection and characterization of circulating endothelial progenitor cells in normal rat blood

Transcriptional Profiling of Laser Capture Microdissected Rat Arterial Elements: Fenoldopam-induced Vascular Toxicity as a Model System

Industry Survey of Approaches to Examination and Terminology of Spontaneous Changes in the Heart of Young Rats

Etomoxir-Induced Oxidative Stress in HepG2 Cells Detected by Differential Gene Expression Is Confirmed Biochemically

Staurosporine-induced Apoptosis in Cardiomyocytes: A Potential Role of Caspase-3

Response to Nyska and Gruebbel

Confounding effects of platelets on flow cytometric analysis and cell‐sorting experiments using blood‐derived cells

Correlative Confocal and Light Microscopic Analysis of Rat Scalp Skin

Prolonged Cell-cycle Arrest Associated with Altered cdc2 Kinase in Monocrotaline Pyrrole-treated Pulmonary Artery Endothelial Cells

Differences in pathogenicity of herpes simplex virus serotypes 1 and 2 may be observed by histopathology and high-resolution magnetic resonance imaging in a murine encephalitis model

Immunolocalization Of Phosphodiesterase Isoenzymes In Rat Tissues Using Confocal Microscopy

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