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Intracellular sorting and transcytosis of the rat transferrin receptor antibody OX26 across the blood–brain barrier in vitro is dependent on its binding affinity

Journal of neurochemistry, 2018-09, Vol.146 (6), p.735-752

2018

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Is There an Optimal Diet for Weight Management and Metabolic Health?

Gastroenterology (New York, N.Y. 1943), 2017-05, Vol.152 (7), p.1739-1751

2017

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Enhanced Delivery of Galanin Conjugates to the Brain through Bioengineering of the Anti-Transferrin Receptor Antibody OX26

Molecular pharmaceutics, 2018-04, Vol.15 (4), p.1420-1431

2018

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Brain penetration, target engagement, and disposition of the blood‐brain barrier‐crossing bispecific antibody antagonist of metabotropic glutamate receptor type 1

The FASEB journal, 2016-05, Vol.30 (5), p.1927-1940

2016

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Total Diet Replacement Within an Integrated Intensive Lifestyle Intervention for Remission of Type 2 Diabetes: Lessons From DiRECT

Frontiers in endocrinology (Lausanne), 2022-06, Vol.13, p.888557-888557

2022

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A peptide derived from melanotransferrin delivers a protein-based interleukin 1 receptor antagonist across the BBB and ameliorates neuropathic pain in a preclinical model

Journal of cerebral blood flow and metabolism, 2019-10, Vol.39 (10), p.2074-2088

2019

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Antibodies binding the head domain of P2X4 inhibit channel function and reverse neuropathic pain

Pain (Amsterdam), 2019-09, Vol.160 (9), p.1989-2003

2019

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Antibody-oligonucleotide conjugate achieves CNS delivery in animal models for spinal muscular atrophy

JCI insight, 2022-12, Vol.7 (24)

2022

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Validity of predictive equations to estimate RMR in females with varying BMI

Journal of nutritional science (Cambridge), 2020-01, Vol.9, p.e17, Article e17

2020

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Validity of predictive equations to estimate RMR in females with varying BMI - CORRIGENDUM

Journal of nutritional science (Cambridge), 2020-01, Vol.9, Article e22

2020

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Probing a Protein-Protein Interaction by in vitro Evolution

Proceedings of the National Academy of Sciences - PNAS, 2006-05, Vol.103 (20), p.7619-7624

2006

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Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial

The Lancet (British edition), 2018-02, Vol.391 (10120), p.541-551

2018

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In vitro potency, pharmacokinetic profiles and pharmacological activity of optimized anti-IL-21R antibodies in a mouse model of lupus

mAbs, 2010-05, Vol.2 (3), p.335-346

2010

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Durability of a primary care-led weight-management intervention for remission of type 2 diabetes: 2-year results of the DiRECT open-label, cluster-randomised trial

The lancet. Diabetes & endocrinology, 2019-05, Vol.7 (5), p.344-355

2019

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Enhanced delivery of IL-1 receptor antagonist to the central nervous system as a novel anti-transferrin receptor-IL-1RA fusion reverses neuropathic mechanical hypersensitivity

Pain (Amsterdam), 2017-04, Vol.158 (4), p.660-668

2017

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Delivering the Diabetes Remission Clinical Trial (DiRECT) in primary care: Experiences of healthcare professionals

Diabetic medicine, 2022-03, Vol.39 (3), p.e14752-n/a

2022

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Isolation of blood-brain barrier-crossing antibodies from a phage display library by competitive elution and their ability to penetrate the central nervous system

mAbs, 2018-02, Vol.10 (2), p.304-314

2018

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Su1770 AZD7798: A NEW CCR9 DEPLETING ANTIBODY TO TREAT CROHN'S DISEASE

Gastroenterology (New York, N.Y. 1943), 2023-05, Vol.164 (6), p.S-674-S-674

2023

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The role of appetite-related hormones, adaptive thermogenesis, perceived hunger and stress in long-term weight-loss maintenance: a mixed-methods study

European journal of clinical nutrition, 2020-04, Vol.74 (4), p.622-632

2020

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Weight Loss Maintenance : Physiological, Psychological and Clinical Perspectives

Thom, George

2020

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Participant experiences in the Diabetes REmission Clinical Trial (DiRECT)

Diabetic medicine, 2022-01, Vol.39 (1), p.e14689-n/a

2022

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In vivo mRNA expression of a multi-mechanistic mAb combination protects against Staphylococcus aureus infection

Molecular therapy, 2024-08, Vol.32 (8), p.2505-2518

2024

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Antihypertensive medication needs and blood pressure control with weight loss in the Diabetes Remission Clinical Trial (DiRECT)

Diabetologia, 2021-09, Vol.64 (9), p.1927-1938

2021

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Physical activity, inactivity and sleep during the Diabetes Remission Clinical Trial (DiRECT)

Diabetic medicine, 2023-03, Vol.40 (3), p.e15010-n/a

2023

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Weight loss‐induced increase in fasting ghrelin concentration is a predictor of weight regain: Evidence from the Diabetes Remission Clinical Trial (DiRECT)

Diabetes, obesity & metabolism, 2021-03, Vol.23 (3), p.711-719

2021

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Intracellular sorting and transcytosis of the rat transferrin receptor antibody OX26 across the blood–brain barrier in vitro is dependent on its binding affinity

Is There an Optimal Diet for Weight Management and Metabolic Health?

Enhanced Delivery of Galanin Conjugates to the Brain through Bioengineering of the Anti-Transferrin Receptor Antibody OX26

Brain penetration, target engagement, and disposition of the blood‐brain barrier‐crossing bispecific antibody antagonist of metabotropic glutamate receptor type 1

Total Diet Replacement Within an Integrated Intensive Lifestyle Intervention for Remission of Type 2 Diabetes: Lessons From DiRECT

A peptide derived from melanotransferrin delivers a protein-based interleukin 1 receptor antagonist across the BBB and ameliorates neuropathic pain in a preclinical model

Antibodies binding the head domain of P2X4 inhibit channel function and reverse neuropathic pain

Antibody-oligonucleotide conjugate achieves CNS delivery in animal models for spinal muscular atrophy

Validity of predictive equations to estimate RMR in females with varying BMI

Validity of predictive equations to estimate RMR in females with varying BMI - CORRIGENDUM

Probing a Protein-Protein Interaction by in vitro Evolution

Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial

In vitro potency, pharmacokinetic profiles and pharmacological activity of optimized anti-IL-21R antibodies in a mouse model of lupus

Durability of a primary care-led weight-management intervention for remission of type 2 diabetes: 2-year results of the DiRECT open-label, cluster-randomised trial

Enhanced delivery of IL-1 receptor antagonist to the central nervous system as a novel anti-transferrin receptor-IL-1RA fusion reverses neuropathic mechanical hypersensitivity

Delivering the Diabetes Remission Clinical Trial (DiRECT) in primary care: Experiences of healthcare professionals

Isolation of blood-brain barrier-crossing antibodies from a phage display library by competitive elution and their ability to penetrate the central nervous system

Su1770 AZD7798: A NEW CCR9 DEPLETING ANTIBODY TO TREAT CROHN'S DISEASE

The role of appetite-related hormones, adaptive thermogenesis, perceived hunger and stress in long-term weight-loss maintenance: a mixed-methods study

Weight Loss Maintenance : Physiological, Psychological and Clinical Perspectives

Participant experiences in the Diabetes REmission Clinical Trial (DiRECT)

In vivo mRNA expression of a multi-mechanistic mAb combination protects against Staphylococcus aureus infection

Antihypertensive medication needs and blood pressure control with weight loss in the Diabetes Remission Clinical Trial (DiRECT)

Physical activity, inactivity and sleep during the Diabetes Remission Clinical Trial (DiRECT)

Weight loss‐induced increase in fasting ghrelin concentration is a predictor of weight regain: Evidence from the Diabetes Remission Clinical Trial (DiRECT)

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