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Design of SARS-CoV-2 PLpro Inhibitors for COVID-19 Antiviral Therapy Leveraging Binding Cooperativity

Journal of medicinal chemistry, 2022-02, Vol.65 (4), p.2940-2955

2022

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Uniform California Earthquake Rupture Forecast, Version 3 (UCERF3)--The Time-Independent Model

Bulletin of the Seismological Society of America, 2014-06, Vol.104 (3), p.1122-1180

2014

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EEG and intelligence: Relations between EEG coherence, EEG phase delay and power

Clinical neurophysiology, 2005-09, Vol.116 (9), p.2129-2141

2005

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Cortical Proteins Associated With Cognitive Resilience in Community-Dwelling Older Persons

JAMA psychiatry (Chicago, Ill.), 2020-11, Vol.77 (11), p.1172

2020

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Potential Mechanisms of Estrogen Quinone Carcinogenesis

Chemical research in toxicology, 2008-01, Vol.21 (1), p.93-101

2008

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Genome-Wide Analysis of Alternative Splicing in Zea mays: Landscape and Genetic Regulation

The Plant cell, 2014-09, Vol.26 (9), p.3472-3487

2014

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Novel Selective Estrogen Receptor Downregulators (SERDs) Developed against Treatment-Resistant Breast Cancer

Journal of medicinal chemistry, 2017-02, Vol.60 (4), p.1325-1342

2017

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Non-covalent inhibitors of thioredoxin glutathione reductase with schistosomicidal activity in vivo

Nature communications, 2023-06, Vol.14 (1), p.3737-3737, Article 3737

2023

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Immunotherapy in Biliary Tract Cancers: Current Standard-of-Care and Emerging Strategies

Cancers, 2023-06, Vol.15 (13), p.3312

2023

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Design and Synthesis of Basic Selective Estrogen Receptor Degraders for Endocrine Therapy Resistant Breast Cancer

Journal of medicinal chemistry, 2019-12, Vol.62 (24), p.11301-11323

2019

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MAP4K4 promotes pancreatic tumorigenesis via phosphorylation and activation of mixed lineage kinase 3

Oncogene, 2021-10, Vol.40 (43), p.6153-6165

2021

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Practitioner Review: Neurobiological consequences of childhood maltreatment – clinical and therapeutic implications for practitioners

Journal of child psychology and psychiatry, 2024-03, Vol.65 (3), p.369-380

2024

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Filtering of deep sequencing data reveals the existence of abundant Dicer-dependent small RNAs derived from tRNAs

RNA (Cambridge), 2009-12, Vol.15 (12), p.2147-2160

2009

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Novel Pyrrolopyridone Bromodomain and Extra-Terminal Motif (BET) Inhibitors Effective in Endocrine-Resistant ER+ Breast Cancer with Acquired Resistance to Fulvestrant and Palbociclib

Journal of medicinal chemistry, 2020-07, Vol.63 (13), p.7186-7210

2020

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Evidence for distinct mechanisms of small molecule inhibitors of filovirus entry

PLoS pathogens, 2021-02, Vol.17 (2), p.e1009312-e1009312

2021

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TrkA expression directs the anti-neoplastic activity of MLK3 inhibitors in triple-negative breast cancer

Oncogene, 2023-03, Vol.42 (14), p.1132-1143

2023

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Optimization of 4‑Aminopiperidines as Inhibitors of Influenza A Viral Entry That Are Synergistic with Oseltamivir

Journal of medicinal chemistry, 2020-03, Vol.63 (6), p.3120-3130

2020

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Fragment-Based Discovery of a Regulatory Site in Thioredoxin Glutathione Reductase Acting as “Doorstop” for NADPH Entry

ACS chemical biology, 2018-08, Vol.13 (8), p.2190-2202

2018

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Discovery and Structural Optimization of 4‑(Aminomethyl)benzamides as Potent Entry Inhibitors of Ebola and Marburg Virus Infections

Journal of medicinal chemistry, 2020-07, Vol.63 (13), p.7211-7225

2020

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Inhibition of ACAT as a Therapeutic Target for Alzheimer's Disease Is Independent of ApoE4 Lipidation

Neurotherapeutics, 2023-07, Vol.20 (4), p.1120-1137

2023

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Non-Covalent Inhibitors of SARS-CoV‑2 Papain-Like Protease (PLpro): In Vitro and In Vivo Antiviral Activity

Journal of medicinal chemistry, 2024-08, Vol.67 (16), p.13681-13702

2024

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A moist aquaplanet variant of the Held–Suarez test for atmospheric model dynamical cores

Geoscientific Model Development, 2016-04, Vol.9 (4), p.1263-1292

2016

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Time-Gated Luminescence Detection of Enzymatically Produced Hydrogen Sulfide: Design, Synthesis, and Application of a Lanthanide-Based Probe

Inorganic chemistry, 2018-01, Vol.57 (2), p.681-688

2018

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Screening and Reverse-Engineering of Estrogen Receptor Ligands as Potent Pan-Filovirus Inhibitors

Journal of medicinal chemistry, 2020-10, Vol.63 (19), p.11085-11099

2020

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G1T48, an oral selective estrogen receptor degrader, and the CDK4/6 inhibitor lerociclib inhibit tumor growth in animal models of endocrine-resistant breast cancer

Breast cancer research and treatment, 2020-04, Vol.180 (3), p.635-646

2020

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Design of SARS-CoV-2 PLpro Inhibitors for COVID-19 Antiviral Therapy Leveraging Binding Cooperativity

Uniform California Earthquake Rupture Forecast, Version 3 (UCERF3)--The Time-Independent Model

EEG and intelligence: Relations between EEG coherence, EEG phase delay and power

Cortical Proteins Associated With Cognitive Resilience in Community-Dwelling Older Persons

Potential Mechanisms of Estrogen Quinone Carcinogenesis

Genome-Wide Analysis of Alternative Splicing in Zea mays: Landscape and Genetic Regulation

Novel Selective Estrogen Receptor Downregulators (SERDs) Developed against Treatment-Resistant Breast Cancer

Non-covalent inhibitors of thioredoxin glutathione reductase with schistosomicidal activity in vivo

Immunotherapy in Biliary Tract Cancers: Current Standard-of-Care and Emerging Strategies

Design and Synthesis of Basic Selective Estrogen Receptor Degraders for Endocrine Therapy Resistant Breast Cancer

MAP4K4 promotes pancreatic tumorigenesis via phosphorylation and activation of mixed lineage kinase 3

Practitioner Review: Neurobiological consequences of childhood maltreatment – clinical and therapeutic implications for practitioners

Filtering of deep sequencing data reveals the existence of abundant Dicer-dependent small RNAs derived from tRNAs

Novel Pyrrolopyridone Bromodomain and Extra-Terminal Motif (BET) Inhibitors Effective in Endocrine-Resistant ER+ Breast Cancer with Acquired Resistance to Fulvestrant and Palbociclib

Evidence for distinct mechanisms of small molecule inhibitors of filovirus entry

TrkA expression directs the anti-neoplastic activity of MLK3 inhibitors in triple-negative breast cancer

Optimization of 4‑Aminopiperidines as Inhibitors of Influenza A Viral Entry That Are Synergistic with Oseltamivir

Fragment-Based Discovery of a Regulatory Site in Thioredoxin Glutathione Reductase Acting as “Doorstop” for NADPH Entry

Discovery and Structural Optimization of 4‑(Aminomethyl)benzamides as Potent Entry Inhibitors of Ebola and Marburg Virus Infections

Inhibition of ACAT as a Therapeutic Target for Alzheimer's Disease Is Independent of ApoE4 Lipidation

Non-Covalent Inhibitors of SARS-CoV‑2 Papain-Like Protease (PLpro): In Vitro and In Vivo Antiviral Activity

A moist aquaplanet variant of the Held–Suarez test for atmospheric model dynamical cores

Time-Gated Luminescence Detection of Enzymatically Produced Hydrogen Sulfide: Design, Synthesis, and Application of a Lanthanide-Based Probe

Screening and Reverse-Engineering of Estrogen Receptor Ligands as Potent Pan-Filovirus Inhibitors

G1T48, an oral selective estrogen receptor degrader, and the CDK4/6 inhibitor lerociclib inhibit tumor growth in animal models of endocrine-resistant breast cancer

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