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Statistical controversies in clinical research: scientific and ethical problems with adaptive randomization in comparative clinical trials

Annals of oncology, 2015-08, Vol.26 (8), p.1621-1628

2015

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Phase I–II clinical trial design: a state-of-the-art paradigm for dose finding

Annals of oncology, 2018-03, Vol.29 (3), p.694-699

2018

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A phase II randomized trial of induction chemotherapy versus no induction chemotherapy followed by preoperative chemoradiation in patients with esophageal cancer

Annals of oncology, 2013-11, Vol.24 (11), p.2844-2849

2013

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PR1 peptide vaccine induces specific immunity with clinical responses in myeloid malignancies

Leukemia, 2017-03, Vol.31 (3), p.697-704

2017

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Fludarabine with pharmacokinetically guided IV busulfan is superior to fixed-dose delivery in pretransplant conditioning of AML/MDS patients

Bone marrow transplantation (Basingstoke), 2017-04, Vol.52 (4), p.580-587

2017

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Randomized, Double-Blinded, Placebo-controlled Multicenter Adaptive Phase 1-2 Trial of GC 4419, a Dismutase Mimetic, in Combination with High Dose Stereotactic Body Radiation Therapy (SBRT) in Locally Advanced Pancreatic Cancer (PC)

International journal of radiation oncology, biology, physics, 2020-12, Vol.108 (5), p.1399-1400

2020

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Leukemia cell mobilization with G-CSF plus plerixafor during busulfan–fludarabine conditioning for allogeneic stem cell transplantation

Bone marrow transplantation (Basingstoke), 2015-07, Vol.50 (7), p.939-946

2015

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Adenoviral infections in adult allogeneic hematopoietic SCT recipients: a single center experience

Bone marrow transplantation (Basingstoke), 2013-09, Vol.48 (9), p.1218-1223

2013

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Phase I/II study of the hypoxia-activated prodrug PR104 in refractory/relapsed acute myeloid leukemia and acute lymphoblastic leukemia

Haematologica (Roma), 2015-07, Vol.100 (7), p.927-934

2015

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Phase I/II trial of lenalidomide and high-dose melphalan with autologous stem cell transplantation for relapsed myeloma

Leukemia, 2015-09, Vol.29 (9), p.1945-1948

2015

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Phase I II study of gemtuzumab ozogamicin added to fludarabine, melphalan and allogeneic hematopoietic stem cell transplantation for high-risk CD33 positive myeloid leukemias and myelodysplastic syndrome

Leukemia, 2008-02, Vol.22 (2), p.258-264

2008

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Intravenous BU plus Mel: an effective, chemotherapy-only transplant conditioning regimen in patients with ALL

Bone marrow transplantation (Basingstoke), 2013-01, Vol.48 (1), p.26-31

2013

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A Strategy for Dose-Finding and Safety Monitoring Based on Efficacy and Adverse Outcomes in Phase I/II Clinical Trials

Biometrics, 1998-03, Vol.54 (1), p.251-264

1998

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A phase I trial of mesenchymal stem cells transfected with a plasmid secreting interferon beta in advanced ovarian cancer

Cytotherapy (Oxford, England), 2018-05, Vol.20 (5), p.S11-S12

2018

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Treatment of newly diagnosed acute promyelocytic leukemia without cytarabine

Journal of clinical oncology, 1997-02, Vol.15 (2), p.483-490

1997

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Prognostic indicators for blood and marrow transplant patients admitted to an intensive care unit

American journal of respiratory and critical care medicine, 1998-09, Vol.158 (3), p.876-884

1998

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Bayesian sequential monitoring designs for single-arm clinical trials with multiple outcomes

Statistics in medicine, 1995-02, Vol.14 (4), p.357-379

1995

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Comparison of 100-day mortality rates associated with i.v. busulfan and cyclophosphamide vs other preparative regimens in allogeneic bone marrow transplantation for chronic myelogenous leukemia: Bayesian sensitivity analyses of confounded treatment and center effects

Bone marrow transplantation (Basingstoke), 2004-06, Vol.33 (12), p.1191-1199

2004

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Some extensions and applications of a Bayesian strategy for monitoring multiple outcomes in clinical trials

Statistics in medicine, 1998-07, Vol.17 (14), p.1563-1580

1998

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Evaluating multiple treatment courses in clinical trials

Statistics in medicine, 2000-04, Vol.19 (8), p.1011-1028

2000

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Utility‐based Bayesian personalized treatment selection for advanced breast cancer

Journal of the Royal Statistical Society. Series C, Applied statistics, 2022-11, Vol.71 (5), p.O1-O1

2022

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Practical Bayesian Guidelines for Phase IIB Clinical Trials

Biometrics, 1994-06, Vol.50 (2), p.337-349

1994

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Caspase 2 and Caspase 3 Protein Levels as Predictors of Survival in Acute Myelogenous Leukemia

Blood, 1998-11, Vol.92 (9), p.3090-3097

1998

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Dynamic change in phosphorylated platelet-derived growth factor receptor in peripheral blood leukocytes following docetaxel therapy predicts progression-free and overall survival in prostate cancer

British journal of cancer, 2008-11, Vol.99 (9), p.1426-1432

2008

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Statistical controversies in clinical research: scientific and ethical problems with adaptive randomization in comparative clinical trials

Phase I–II clinical trial design: a state-of-the-art paradigm for dose finding

A phase II randomized trial of induction chemotherapy versus no induction chemotherapy followed by preoperative chemoradiation in patients with esophageal cancer

PR1 peptide vaccine induces specific immunity with clinical responses in myeloid malignancies

Fludarabine with pharmacokinetically guided IV busulfan is superior to fixed-dose delivery in pretransplant conditioning of AML/MDS patients

Randomized, Double-Blinded, Placebo-controlled Multicenter Adaptive Phase 1-2 Trial of GC 4419, a Dismutase Mimetic, in Combination with High Dose Stereotactic Body Radiation Therapy (SBRT) in Locally Advanced Pancreatic Cancer (PC)

Leukemia cell mobilization with G-CSF plus plerixafor during busulfan–fludarabine conditioning for allogeneic stem cell transplantation

Adenoviral infections in adult allogeneic hematopoietic SCT recipients: a single center experience

Phase I/II study of the hypoxia-activated prodrug PR104 in refractory/relapsed acute myeloid leukemia and acute lymphoblastic leukemia

Phase I/II trial of lenalidomide and high-dose melphalan with autologous stem cell transplantation for relapsed myeloma

Phase I II study of gemtuzumab ozogamicin added to fludarabine, melphalan and allogeneic hematopoietic stem cell transplantation for high-risk CD33 positive myeloid leukemias and myelodysplastic syndrome

Intravenous BU plus Mel: an effective, chemotherapy-only transplant conditioning regimen in patients with ALL

Melphalan and purine analog–containing preparative regimens: reduced-intensity conditioning for patients with hematologic malignancies undergoing allogeneic progenitor cell transplantation

A Strategy for Dose-Finding and Safety Monitoring Based on Efficacy and Adverse Outcomes in Phase I/II Clinical Trials

A phase I trial of mesenchymal stem cells transfected with a plasmid secreting interferon beta in advanced ovarian cancer

Treatment of newly diagnosed acute promyelocytic leukemia without cytarabine

Prognostic indicators for blood and marrow transplant patients admitted to an intensive care unit

Bayesian sequential monitoring designs for single-arm clinical trials with multiple outcomes

Comparison of 100-day mortality rates associated with i.v. busulfan and cyclophosphamide vs other preparative regimens in allogeneic bone marrow transplantation for chronic myelogenous leukemia: Bayesian sensitivity analyses of confounded treatment and center effects

Some extensions and applications of a Bayesian strategy for monitoring multiple outcomes in clinical trials

Evaluating multiple treatment courses in clinical trials

Utility‐based Bayesian personalized treatment selection for advanced breast cancer

Practical Bayesian Guidelines for Phase IIB Clinical Trials

Caspase 2 and Caspase 3 Protein Levels as Predictors of Survival in Acute Myelogenous Leukemia

Dynamic change in phosphorylated platelet-derived growth factor receptor in peripheral blood leukocytes following docetaxel therapy predicts progression-free and overall survival in prostate cancer

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