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Iberdomide (CC-220) is a potent cereblon E3 ligase modulator with antitumor and immunostimulatory activities in lenalidomide- and pomalidomide-resistant multiple myeloma cells with dysregulated CRBN

Leukemia, 2020-04, Vol.34 (4), p.1197-1201

2020

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Nanopore sequencing of single-cell transcriptomes with scCOLOR-seq

Nature biotechnology, 2021-12, Vol.39 (12), p.1517-1520

2021

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Enasidenib induces acute myeloid leukemia cell differentiation to promote clinical response

Blood, 2017-08, Vol.130 (6), p.732-741

2017

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Extended exposure to low doses of azacitidine induces differentiation of leukemic stem cells through activation of myeloperoxidase

Haematologica (Roma), 2024-04, Vol.109 (4), p.1082

2024

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Genome-Wide Somatic Alterations in Multiple Myeloma Reveal a Superior Outcome Group

Journal of clinical oncology, 2020-09, Vol.38 (27), p.3107-3118

2020

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The Next Frontier: Translational Development of Ubiquitination, SUMOylation, and NEDDylation in Cancer

International journal of molecular sciences, 2022-03, Vol.23 (7), p.3480

2022

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Clinical and pharmacodynamic analysis of pomalidomide dosing strategies in myeloma: impact of immune activation and cereblon targets

Blood, 2015-06, Vol.125 (26), p.4042-4051

2015

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Prognosis, Biology, and Targeting of TP53 Dysregulation in Multiple Myeloma

Cells (Basel, Switzerland), 2020-01, Vol.9 (2), p.287

2020

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Differential RNA splicing as a potentially important driver mechanism in multiple myeloma

Haematologica (Roma), 2021-03, Vol.106 (3), p.736-745

2021

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Microhomology-mediated end joining drives complex rearrangements and overexpression of MYC and PVT1 in multiple myeloma

Haematologica (Roma), 2020-04, Vol.105 (4), p.1055-1066

2020

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Cereblon loss and up-regulation of c-Myc are associated with lenalidomide resistance in multiple myeloma patients

Haematologica (Roma), 2018-08, Vol.103 (8), p.e368-e371

2018

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Measuring cereblon as a biomarker of response or resistance to lenalidomide and pomalidomide requires use of standardized reagents and understanding of gene complexity

British journal of haematology, 2014-01, Vol.164 (2), p.233-244

2014

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Multiple Myeloma Patient Tumors With High Levels of Cereblon Exon-10 Deletion Splice Variant Upregulate Clinically Targetable Pro-Inflammatory Cytokine Pathways

Frontiers in genetics, 2022-02, Vol.13, p.831779-831779

2022

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Multiple myeloma and its treatment contribute to increased platelet reactivity

Platelets (Edinburgh), 2023-12, Vol.34 (1), p.2264940-2264940

2023

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Integrative multi-omics identifies high risk multiple myeloma subgroup associated with significant DNA loss and dysregulated DNA repair and cell cycle pathways

BMC medical genomics, 2021-12, Vol.14 (1), p.295-295, Article 295

2021

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Prolyl-tRNA synthetase as a novel therapeutic target in multiple myeloma

Blood cancer journal (New York), 2023-01, Vol.13 (1), p.12-12, Article 12

2023

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Correction: Prolyl-tRNA synthetase as a novel therapeutic target in multiple myeloma

Blood cancer journal (New York), 2023-02, Vol.13 (1), p.24-24, Article 24

2023

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A Dual Color Immunohistochemistry Assay for Measurement of Cereblon in Multiple Myeloma Patient Samples

Applied immunohistochemistry & molecular morphology, 2016-11, Vol.24 (10), p.695-702

2016

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Pomalidomide + Low-Dose Dexamethasone Following Second-Line Lenalidomide-Based Therapy in Relapsed or Refractory Multiple Myeloma: A Phase 2 Study Investigating Efficacy and Safety

Blood, 2016-12, Vol.128 (22), p.4497-4497

2016

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Homolog of BRCA2-interacting Dss1p and Uap56p link Mlo3p and Rae1p for mRNA export in fission yeast

The EMBO journal, 2005-07, Vol.24 (14), p.2512-2523

2005

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Iberdomide (CC-220) is a potent cereblon E3 ligase modulator with antitumor and immunostimulatory activities in lenalidomide- and pomalidomide-resistant multiple myeloma cells with dysregulated CRBN

Nanopore sequencing of single-cell transcriptomes with scCOLOR-seq

Enasidenib induces acute myeloid leukemia cell differentiation to promote clinical response

Identification of novel mutational drivers reveals oncogene dependencies in multiple myeloma

A high-risk, Double-Hit, group of newly diagnosed myeloma identified by genomic analysis

A Phase 2/3 Multicenter, Randomized, Open-Label Study to Compare the Efficacy and Safety of Lenalidomide Versus Investigator's Choice in Patients with Relapsed or Refractory Diffuse Large B-Cell Lymphoma

Extended exposure to low doses of azacitidine induces differentiation of leukemic stem cells through activation of myeloperoxidase

Genome-Wide Somatic Alterations in Multiple Myeloma Reveal a Superior Outcome Group

CC-122, a pleiotropic pathway modifier, mimics an interferon response and has antitumor activity in DLBCL

The Next Frontier: Translational Development of Ubiquitination, SUMOylation, and NEDDylation in Cancer

Clinical and pharmacodynamic analysis of pomalidomide dosing strategies in myeloma: impact of immune activation and cereblon targets

Prognosis, Biology, and Targeting of TP53 Dysregulation in Multiple Myeloma

Differential RNA splicing as a potentially important driver mechanism in multiple myeloma

Microhomology-mediated end joining drives complex rearrangements and overexpression of MYC and PVT1 in multiple myeloma

Cereblon loss and up-regulation of c-Myc are associated with lenalidomide resistance in multiple myeloma patients

Measuring cereblon as a biomarker of response or resistance to lenalidomide and pomalidomide requires use of standardized reagents and understanding of gene complexity

Multiple Myeloma Patient Tumors With High Levels of Cereblon Exon-10 Deletion Splice Variant Upregulate Clinically Targetable Pro-Inflammatory Cytokine Pathways

Multiple myeloma and its treatment contribute to increased platelet reactivity

Integrative multi-omics identifies high risk multiple myeloma subgroup associated with significant DNA loss and dysregulated DNA repair and cell cycle pathways

Immunomodulation of NK, NKT and B/T cell subtypes in relapsed/refractory multiple myeloma patients treated with pomalidomide along with velcade and dexamethasone and its association with improved progression-free survival

Prolyl-tRNA synthetase as a novel therapeutic target in multiple myeloma

Correction: Prolyl-tRNA synthetase as a novel therapeutic target in multiple myeloma

A Dual Color Immunohistochemistry Assay for Measurement of Cereblon in Multiple Myeloma Patient Samples

Pomalidomide + Low-Dose Dexamethasone Following Second-Line Lenalidomide-Based Therapy in Relapsed or Refractory Multiple Myeloma: A Phase 2 Study Investigating Efficacy and Safety

Homolog of BRCA2-interacting Dss1p and Uap56p link Mlo3p and Rae1p for mRNA export in fission yeast

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