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Combination Treatment of a Phytochemical and a Histone Demethylase Inhibitor-A Novel Approach towards Targeting TGFβ-Induced EMT, Invasion, and Migration in Prostate Cancer

International journal of molecular sciences, 2023-01, Vol.24 (3), p.1860

2023

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Global Gene Expression Regulation Mediated by TGFβ Through H3K9me3 Mark

Cancer informatics, 2022-07, Vol.21, p.117693512211151-11769351221115135

2022

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Global Histone H3 Lysine 4 Trimethylation (H3K4me3) Landscape Changes in Response to TGFβ

Epigenetics insights, 2021, Vol.14, p.251686572110517-25168657211051755

2021

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Smad7 Enhances TGF-β-Induced Transcription of c-Jun and HDAC6 Promoting Invasion of Prostate Cancer Cells

iScience, 2020-09, Vol.23 (9), p.101470-101470, Article 101470

2020

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The length of the transcript encoded from the Kcnq1ot1 antisense promoter determines the degree of silencing

The EMBO journal, 2006-05, Vol.25 (10), p.2096-2106

2006

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GSK-J4: An H3K27 histone demethylase inhibitor, as a potential anti-cancer agent

International journal of cancer, 2023-09, Vol.153 (6), p.1130-1138

2023

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An Antisense RNA Regulates the Bidirectional Silencing Property of the Kcnq1 Imprinting Control Region

Molecular and Cellular Biology, 2004-09, Vol.24 (18), p.7855-7862

2004

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Comparative analysis of the occupancy of Histone H3 Lysine 4 methylation in the cells treated with TGFβ and Interferonγ

Gene, 2023-08, Vol.879, p.147601-147601, Article 147601

2023

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TGFβ1-Induced Activation of ATM and p53 Mediates Apoptosis in a Smad7-Dependent Manner

Cell cycle (Georgetown, Tex.), 2006-12, Vol.5 (23), p.2787-2795

2006

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TGF-β promotes PI3K-AKT signaling and prostate cancer cell migration through the TRAF6-mediated ubiquitylation of p85α

Science signaling, 2017-07, Vol.10 (486)

2017

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The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner

Nature cell biology, 2008-10, Vol.10 (10), p.1199-1207

2008

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Bidirectional Silencing and DNA Methylation-sensitive Methylation-spreading Properties of the Kcnq1 Imprinting Control Region Map to the Same Regions

The Journal of biological chemistry, 2003-03, Vol.278 (11), p.9514-9519

2003

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TRAF6 ubiquitinates TGFβ type I receptor to promote its cleavage and nuclear translocation in cancer

Nature communications, 2011, Vol.2 (1), p.330-330, Article 330

2011

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TGFβ-induced invasion of prostate cancer cells is promoted by c-Jun-dependent transcriptional activation of Snail1

Cell cycle (Georgetown, Tex.), 2014-08, Vol.13 (15), p.2400-2414

2014

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Smad7 Enhances TGF-b-Induced Transcription of c-Jun and HDAC6 Promoting Invasion of Prostate Cancer Cells

iScience, 2020, Vol.23 (9)

2020

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APC and Smad7 link TGFβ type I receptors to the microtubule system to promote cell migration

Molecular biology of the cell, 2012-06, Vol.23 (11), p.2109-2121

2012

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TGFβ-induced invasion of prostate cancer cells is promoted by c-Jun-dependent transcriptional activation of Snail1

Cell cycle (Georgetown, Tex.), 2014-06, Vol.13 (15), p.2400-2414

2014

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TGF beta 1-induced activation of ATM and p53 mediates apoptosis in a Smad7-dependent manner

Cell cycle (Georgetown, Tex.), 2006-12, Vol.5 (23), p.2787

2006

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TGF-b[beta] uses the E3-ligase TRAF6 to turn on the kinase TAK1 to kill prostate cancer cells

Future oncology (London, England), 2009-02, Vol.5 (1), p.1

2009

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TGF- β uses the E3-ligase TRAF6 to turn on the kinase TAK1 to kill prostate cancer cells

Future oncology (London, England), 2009-02, Vol.5 (1), p.1-3

2009

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The type I TGF-[beta] receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner

Nature cell biology, 2008-10, Vol.10 (10), p.1199

2008

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Long-range control of gene expression by imprinting control regions during development and neoplasia

Thakur, Noopur

2005

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TRAF6 ubiquitinates TGF[beta] type I receptor to promote its cleavage and nuclear translocation in cancer

Nature communications, 2011-05, Vol.2, p.330

2011

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The kinetics of deregulation of expression by de novo methylation of the H19 imprinting control region in cancer cells

Cancer research (Chicago, Ill.), 2002-08, Vol.62 (16), p.4545-4548

2002

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TGFbeta1-induced activation of ATM and p53 mediates apoptosis in a Smad7-dependent manner

Cell cycle (Georgetown, Tex.), 2006-12, Vol.5 (23), p.2787-2795

2006

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Combination Treatment of a Phytochemical and a Histone Demethylase Inhibitor-A Novel Approach towards Targeting TGFβ-Induced EMT, Invasion, and Migration in Prostate Cancer

Global Gene Expression Regulation Mediated by TGFβ Through H3K9me3 Mark

Global Histone H3 Lysine 4 Trimethylation (H3K4me3) Landscape Changes in Response to TGFβ

Smad7 Enhances TGF-β-Induced Transcription of c-Jun and HDAC6 Promoting Invasion of Prostate Cancer Cells

The length of the transcript encoded from the Kcnq1ot1 antisense promoter determines the degree of silencing

GSK-J4: An H3K27 histone demethylase inhibitor, as a potential anti-cancer agent

An Antisense RNA Regulates the Bidirectional Silencing Property of the Kcnq1 Imprinting Control Region

Comparative analysis of the occupancy of Histone H3 Lysine 4 methylation in the cells treated with TGFβ and Interferonγ

TGFβ1-Induced Activation of ATM and p53 Mediates Apoptosis in a Smad7-Dependent Manner

TGF-β promotes PI3K-AKT signaling and prostate cancer cell migration through the TRAF6-mediated ubiquitylation of p85α

The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner

Bidirectional Silencing and DNA Methylation-sensitive Methylation-spreading Properties of the Kcnq1 Imprinting Control Region Map to the Same Regions

TRAF6 ubiquitinates TGFβ type I receptor to promote its cleavage and nuclear translocation in cancer

TGFβ-induced invasion of prostate cancer cells is promoted by c-Jun-dependent transcriptional activation of Snail1

Smad7 Enhances TGF-b-Induced Transcription of c-Jun and HDAC6 Promoting Invasion of Prostate Cancer Cells

APC and Smad7 link TGFβ type I receptors to the microtubule system to promote cell migration

TGFβ-induced invasion of prostate cancer cells is promoted by c-Jun-dependent transcriptional activation of Snail1

TGF beta 1-induced activation of ATM and p53 mediates apoptosis in a Smad7-dependent manner

TGF-b[beta] uses the E3-ligase TRAF6 to turn on the kinase TAK1 to kill prostate cancer cells

TGF- β uses the E3-ligase TRAF6 to turn on the kinase TAK1 to kill prostate cancer cells

The type I TGF-[beta] receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner

Long-range control of gene expression by imprinting control regions during development and neoplasia

TRAF6 ubiquitinates TGF[beta] type I receptor to promote its cleavage and nuclear translocation in cancer

The kinetics of deregulation of expression by de novo methylation of the H19 imprinting control region in cancer cells

TGFbeta1-induced activation of ATM and p53 mediates apoptosis in a Smad7-dependent manner

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