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Combination Treatment of a Phytochemical and a Histone Demethylase Inhibitor-A Novel Approach towards Targeting TGFβ-Induced EMT, Invasion, and Migration in Prostate Cancer

International journal of molecular sciences, 2023-01, Vol.24 (3), p.1860

2023

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Global Gene Expression Regulation Mediated by TGFβ Through H3K9me3 Mark

Cancer informatics, 2022-07, Vol.21, p.117693512211151-11769351221115135

2022

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Hesperetin modulates TGFβ induced metastatic potential of prostate cancer cells by altering histone methylation marks

Advances in cancer biology - metastasis, 2022-12, Vol.6, p.100077, Article 100077

2022

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Global Histone H3 Lysine 4 Trimethylation (H3K4me3) Landscape Changes in Response to TGFβ

Epigenetics insights, 2021, Vol.14, p.251686572110517-25168657211051755

2021

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Smad7 Enhances TGF-β-Induced Transcription of c-Jun and HDAC6 Promoting Invasion of Prostate Cancer Cells

iScience, 2020-09, Vol.23 (9), p.101470-101470, Article 101470

2020

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The length of the transcript encoded from the Kcnq1ot1 antisense promoter determines the degree of silencing

The EMBO journal, 2006-05, Vol.25 (10), p.2096-2106

2006

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GSK-J4: An H3K27 histone demethylase inhibitor, as a potential anti-cancer agent

International journal of cancer, 2023-09, Vol.153 (6), p.1130-1138

2023

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An Antisense RNA Regulates the Bidirectional Silencing Property of the Kcnq1 Imprinting Control Region

Molecular and Cellular Biology, 2004-09, Vol.24 (18), p.7855-7862

2004

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Comparative analysis of the occupancy of Histone H3 Lysine 4 methylation in the cells treated with TGFβ and Interferonγ

Gene, 2023-08, Vol.879, p.147601-147601, Article 147601

2023

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TGFβ1-Induced Activation of ATM and p53 Mediates Apoptosis in a Smad7-Dependent Manner

Cell cycle (Georgetown, Tex.), 2006-12, Vol.5 (23), p.2787-2795

2006

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TGF-β promotes PI3K-AKT signaling and prostate cancer cell migration through the TRAF6-mediated ubiquitylation of p85α

Science signaling, 2017-07, Vol.10 (486)

2017

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The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner

Nature cell biology, 2008-10, Vol.10 (10), p.1199-1207

2008

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Bidirectional Silencing and DNA Methylation-sensitive Methylation-spreading Properties of the Kcnq1 Imprinting Control Region Map to the Same Regions

The Journal of biological chemistry, 2003-03, Vol.278 (11), p.9514-9519

2003

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TRAF6 ubiquitinates TGFβ type I receptor to promote its cleavage and nuclear translocation in cancer

Nature communications, 2011, Vol.2 (1), p.330-330, Article 330

2011

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TGFβ-induced invasion of prostate cancer cells is promoted by c-Jun-dependent transcriptional activation of Snail1

Cell cycle (Georgetown, Tex.), 2014-08, Vol.13 (15), p.2400-2414

2014

Volltextzugriff (PDF)

Smad7 Enhances TGF-b-Induced Transcription of c-Jun and HDAC6 Promoting Invasion of Prostate Cancer Cells

iScience, 2020, Vol.23 (9)

2020

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APC and Smad7 link TGFβ type I receptors to the microtubule system to promote cell migration

Molecular biology of the cell, 2012-06, Vol.23 (11), p.2109-2121

2012

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TGFβ-induced invasion of prostate cancer cells is promoted by c-Jun-dependent transcriptional activation of Snail1

Cell cycle (Georgetown, Tex.), 2014-06, Vol.13 (15), p.2400-2414

2014

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TGF beta 1-induced activation of ATM and p53 mediates apoptosis in a Smad7-dependent manner

Cell cycle (Georgetown, Tex.), 2006-12, Vol.5 (23), p.2787

2006

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TGF-b[beta] uses the E3-ligase TRAF6 to turn on the kinase TAK1 to kill prostate cancer cells

Future oncology (London, England), 2009-02, Vol.5 (1), p.1

2009

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TGF- β uses the E3-ligase TRAF6 to turn on the kinase TAK1 to kill prostate cancer cells

Future oncology (London, England), 2009-02, Vol.5 (1), p.1-3

2009

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The type I TGF-[beta] receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner

Nature cell biology, 2008-10, Vol.10 (10), p.1199

2008

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Long-range control of gene expression by imprinting control regions during development and neoplasia

Thakur, Noopur

2005

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TRAF6 ubiquitinates TGF[beta] type I receptor to promote its cleavage and nuclear translocation in cancer

Nature communications, 2011-05, Vol.2, p.330

2011

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The kinetics of deregulation of expression by de novo methylation of the H19 imprinting control region in cancer cells

Cancer research (Chicago, Ill.), 2002-08, Vol.62 (16), p.4545-4548

2002

Volltextzugriff (PDF)

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Combination Treatment of a Phytochemical and a Histone Demethylase Inhibitor-A Novel Approach towards Targeting TGFβ-Induced EMT, Invasion, and Migration in Prostate Cancer

Global Gene Expression Regulation Mediated by TGFβ Through H3K9me3 Mark

Hesperetin modulates TGFβ induced metastatic potential of prostate cancer cells by altering histone methylation marks

Global Histone H3 Lysine 4 Trimethylation (H3K4me3) Landscape Changes in Response to TGFβ

Smad7 Enhances TGF-β-Induced Transcription of c-Jun and HDAC6 Promoting Invasion of Prostate Cancer Cells

The length of the transcript encoded from the Kcnq1ot1 antisense promoter determines the degree of silencing

GSK-J4: An H3K27 histone demethylase inhibitor, as a potential anti-cancer agent

An Antisense RNA Regulates the Bidirectional Silencing Property of the Kcnq1 Imprinting Control Region

Comparative analysis of the occupancy of Histone H3 Lysine 4 methylation in the cells treated with TGFβ and Interferonγ

TGFβ1-Induced Activation of ATM and p53 Mediates Apoptosis in a Smad7-Dependent Manner

TGF-β promotes PI3K-AKT signaling and prostate cancer cell migration through the TRAF6-mediated ubiquitylation of p85α

The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner

Bidirectional Silencing and DNA Methylation-sensitive Methylation-spreading Properties of the Kcnq1 Imprinting Control Region Map to the Same Regions

TRAF6 ubiquitinates TGFβ type I receptor to promote its cleavage and nuclear translocation in cancer

TGFβ-induced invasion of prostate cancer cells is promoted by c-Jun-dependent transcriptional activation of Snail1

Smad7 Enhances TGF-b-Induced Transcription of c-Jun and HDAC6 Promoting Invasion of Prostate Cancer Cells

APC and Smad7 link TGFβ type I receptors to the microtubule system to promote cell migration

TGFβ-induced invasion of prostate cancer cells is promoted by c-Jun-dependent transcriptional activation of Snail1

TGF beta 1-induced activation of ATM and p53 mediates apoptosis in a Smad7-dependent manner

TGF-b[beta] uses the E3-ligase TRAF6 to turn on the kinase TAK1 to kill prostate cancer cells

TGF- β uses the E3-ligase TRAF6 to turn on the kinase TAK1 to kill prostate cancer cells

The type I TGF-[beta] receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner

Long-range control of gene expression by imprinting control regions during development and neoplasia

TRAF6 ubiquitinates TGF[beta] type I receptor to promote its cleavage and nuclear translocation in cancer

The kinetics of deregulation of expression by de novo methylation of the H19 imprinting control region in cancer cells

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