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Interleukin 23 Produced by Hepatic Monocyte-Derived Macrophages Is Essential for the Development of Murine Primary Biliary Cholangitis

Frontiers in immunology, 2021-08, Vol.12, p.718841-718841

2021

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Therapeutic activity of an interleukin‐4/interleukin‐13 dual antagonist on oxazolone‐induced colitis in mice

Immunology, 2014-11, Vol.143 (3), p.416-427

2014

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Mice lacking Tbk1 activity exhibit immune cell infiltrates in multiple tissues and increased susceptibility to LPS-induced lethality

Journal of leukocyte biology, 2010-12, Vol.88 (6), p.1171-1180

2010

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1166 WHOLE GENOME SEQUENCING OF CYCLIC VOMITING PATIENTS REVEALS NOVEL RISK LOCI

Gastroenterology (New York, N.Y. 1943), 2024-05, Vol.166 (5), p.S-276-S-276

2024

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Sa1773 MACHINE LEARNING-BASED PRECISION MEDICINE APPROACH IDENTIFIES SPECIFIC RESPONDER SUB-POPULATIONS IN PATIENTS TREATED WITH VEDOLIZUMAB BY DYNAMIC CLUSTERING OF PRO-2 DATA: POST HOC ANALYSIS OF VARSITY AND CONFIRMATION IN THE GEMINI DATASET

Gastroenterology (New York, N.Y. 1943), 2024-05, Vol.166 (5), p.S-517-S-517

2024

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TH1-mediated airway hyperresponsiveness independent of neutrophilic inflammation

Journal of allergy and clinical immunology, 2005-02, Vol.115 (2), p.309-315

2005

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Human bronchial epithelial cells express and secrete MMP-12

Biochemical and biophysical research communications, 2004-11, Vol.324 (2), p.534-546

2004

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50378 Clinical efficacy of TAK-279, a highly selective oral tyrosine kinase 2 (TYK2) inhibitor, is associated with modulation of disease and TYK2 pathway biomarkers in patients with moderate-to-severe psoriasis

Journal of the American Academy of Dermatology, 2024-09, Vol.91 (3), p.AB159-AB159

2024

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FRI-164 Proteomic analysis identified fazirsiran treatment-responsive protein biomarkers in patients with alpha-1 antitrypsin deficiency-associated liver disease

Journal of hepatology, 2024-06, Vol.80, p.S698-S698

2024

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FRI-161 Correlation of non-invasive tests with histological features and intrahepatic Z-alpha-1 antitrypsin burden in patients with alpha-1 antitrypsin deficiency-associated liver disease

Journal of hepatology, 2024-06, Vol.80, p.S696-S697

2024

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A randomized phase 2 study of the 5-HT 4 receptor agonist felcisetrag for postoperative gastrointestinal dysfunction after bowel surgery

The American journal of surgery, 2024-08, Vol.234, p.162

2024

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A randomized phase 2 study of the 5-HT4 receptor agonist felcisetrag for postoperative gastrointestinal dysfunction after bowel surgery

The American journal of surgery, 2024-08, Vol.234, p.162-171

2024

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NAFLD and NASH biomarker qualification in the LITMUS consortium – Lessons learned

Journal of hepatology, 2023-04, Vol.78 (4), p.852-865

2023

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Comparison of the Inflammatory Circuits in Psoriasis Vulgaris, Non‒Pustular Palmoplantar Psoriasis, and Palmoplantar Pustular Psoriasis

Journal of investigative dermatology, 2023-01, Vol.143 (1), p.87-97.e14

2023

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IL-23-producing IL-10Rα-deficient gut macrophages elicit an IL-22-driven proinflammatory epithelial cell response

Science immunology, 2019-06, Vol.4 (36)

2019

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Performance of non-invasive tests and histology for the prediction of clinical outcomes in patients with non-alcoholic fatty liver disease: an individual participant data meta-analysis

The lancet. Gastroenterology & hepatology, 2023-08, Vol.8 (8), p.704-713

2023

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Machine learning algorithm improves the detection of NASH (NAS-based) and at-risk NASH: A development and validation study

Hepatology (Baltimore, Md.), 2023-07, Vol.78 (1), p.258-271

2023

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IL-23 Is Critical in the Induction but Not in the Effector Phase of Experimental Autoimmune Encephalomyelitis

Journal of Immunology, 2007-02, Vol.178 (4), p.2589-2598

2007

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Noninvasive Longitudinal Study of a Magnetic Resonance Imaging Biomarker for the Quantification of Colon Inflammation in a Mouse Model of Colitis

Inflammatory bowel diseases, 2016-06, Vol.22 (6), p.1286-1295

2016

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Chiral auxiliary mediated pictet-spengler reactions: Asymmetric syntheses of (−)-laudanosine, (+)-glaucine and (−)-xylopinine

Tetrahedron, 1997-12, Vol.53 (48), p.16327-16340

1997

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Design and synthesis of sialyl Lewis x mimics as E-selectin inhibitors

Bioorganic & medicinal chemistry letters, 2001-01, Vol.11 (2), p.151-155

2001

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An unbiased ranking of murine dietary models based on their proximity to human metabolic dysfunction-associated steatotic liver disease (MASLD)

Nature metabolism, 2024-06, Vol.6 (6), p.1178-1196

2024

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Cytosolic phospholipase A2 alpha-deficient mice are resistant to experimental autoimmune encephalomyelitis

The Journal of experimental medicine, 2005-09, Vol.202 (6), p.841-851

2005

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Interleukin 23 Produced by Hepatic Monocyte-Derived Macrophages Is Essential for the Development of Murine Primary Biliary Cholangitis

Therapeutic activity of an interleukin‐4/interleukin‐13 dual antagonist on oxazolone‐induced colitis in mice

Mice lacking Tbk1 activity exhibit immune cell infiltrates in multiple tissues and increased susceptibility to LPS-induced lethality

1166 WHOLE GENOME SEQUENCING OF CYCLIC VOMITING PATIENTS REVEALS NOVEL RISK LOCI

Sa1773 MACHINE LEARNING-BASED PRECISION MEDICINE APPROACH IDENTIFIES SPECIFIC RESPONDER SUB-POPULATIONS IN PATIENTS TREATED WITH VEDOLIZUMAB BY DYNAMIC CLUSTERING OF PRO-2 DATA: POST HOC ANALYSIS OF VARSITY AND CONFIRMATION IN THE GEMINI DATASET

TH1-mediated airway hyperresponsiveness independent of neutrophilic inflammation

Human bronchial epithelial cells express and secrete MMP-12

50378 Clinical efficacy of TAK-279, a highly selective oral tyrosine kinase 2 (TYK2) inhibitor, is associated with modulation of disease and TYK2 pathway biomarkers in patients with moderate-to-severe psoriasis

FRI-164 Proteomic analysis identified fazirsiran treatment-responsive protein biomarkers in patients with alpha-1 antitrypsin deficiency-associated liver disease

FRI-161 Correlation of non-invasive tests with histological features and intrahepatic Z-alpha-1 antitrypsin burden in patients with alpha-1 antitrypsin deficiency-associated liver disease

A randomized phase 2 study of the 5-HT 4 receptor agonist felcisetrag for postoperative gastrointestinal dysfunction after bowel surgery

A randomized phase 2 study of the 5-HT4 receptor agonist felcisetrag for postoperative gastrointestinal dysfunction after bowel surgery

NAFLD and NASH biomarker qualification in the LITMUS consortium – Lessons learned

WED-294 The use of the FibroScan-AST score and AST to pre-identify metabolic dysfunction-associated steatohepatitis patients with active fibrogenesis in a Phase 1b open-label clinical trial

Comparison of the Inflammatory Circuits in Psoriasis Vulgaris, Non‒Pustular Palmoplantar Psoriasis, and Palmoplantar Pustular Psoriasis

IL-23-producing IL-10Rα-deficient gut macrophages elicit an IL-22-driven proinflammatory epithelial cell response

Performance of non-invasive tests and histology for the prediction of clinical outcomes in patients with non-alcoholic fatty liver disease: an individual participant data meta-analysis

Machine learning algorithm improves the detection of NASH (NAS-based) and at-risk NASH: A development and validation study

IL-23 Is Critical in the Induction but Not in the Effector Phase of Experimental Autoimmune Encephalomyelitis

Noninvasive Longitudinal Study of a Magnetic Resonance Imaging Biomarker for the Quantification of Colon Inflammation in a Mouse Model of Colitis

Chiral auxiliary mediated pictet-spengler reactions: Asymmetric syntheses of (−)-laudanosine, (+)-glaucine and (−)-xylopinine

Design and synthesis of sialyl Lewis x mimics as E-selectin inhibitors

An unbiased ranking of murine dietary models based on their proximity to human metabolic dysfunction-associated steatotic liver disease (MASLD)

Cytosolic phospholipase A2 alpha-deficient mice are resistant to experimental autoimmune encephalomyelitis

Indole Cytosolic Phospholipase A2 α Inhibitors: Discovery and in Vitro and in Vivo Characterization of 4-{3-[5-Chloro-2-(2-{[(3,4-dichlorobenzyl)sulfonyl]amino}ethyl)-1-(diphenylmethyl)-1H-indol-3-yl]propyl}benzoic Acid, Efipladib

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