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Myc-induced AMPK-phospho p53 pathway activates Bak to sensitize mitochondrial apoptosis

Proceedings of the National Academy of Sciences - PNAS, 2013-05, Vol.110 (20), p.E1839-E1848

2013

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Immunoglobulin superfamily member 3 is required for the vagal neural crest cell migration and enteric neuronal network organization

Scientific reports, 2023-10, Vol.13 (1), p.17162-17162, Article 17162

2023

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Hepsin promotes breast tumor growth signaling via the TGFβ‐EGFR axis

Molecular oncology, 2024-03, Vol.18 (3), p.547-561

2024

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Breaking the epithelial polarity barrier in cancer: the strange case of LKB1/PAR-4

Philosophical transactions of the Royal Society of London. Series B. Biological sciences, 2013-11, Vol.368 (1629), p.20130111

2013

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Hepsin regulates TGFβ signaling via fibronectin proteolysis

EMBO reports, 2021-11, Vol.22 (11), p.e52532-n/a

2021

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Oncogenic Ras Disrupts Epithelial Integrity by Activating the Transmembrane Serine Protease Hepsin

Cancer research (Chicago, Ill.), 2021-03, Vol.81 (6), p.1513-1527

2021

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Design, Synthesis, and Testing of Potent, Selective Hepsin Inhibitors via Application of an Automated Closed-Loop Optimization Platform

Journal of medicinal chemistry, 2018-05, Vol.61 (10), p.4335-4347

2018

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Tumor suppressor function of Liver kinase B1 (Lkb1) is linked to regulation of epithelial integrity

Proceedings of the National Academy of Sciences - PNAS, 2012-02, Vol.109 (7), p.2196-2197

2012

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Analyzing the Type II Transmembrane Serine Protease Hepsin-Dependent Basement Membrane Remodeling in 3D Cell Culture

Methods in molecular biology (Clifton, N.J.), 2018-01, Vol.1731, p.169

2018

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Aberrant differentiation of glutamatergic cells in neocortex of mouse model for fragile X syndrome

Neurobiology of disease, 2009-02, Vol.33 (2), p.250-259

2009

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Altered Differentiation of Neural Stem Cells in Fragile X Syndrome

Proceedings of the National Academy of Sciences - PNAS, 2005-12, Vol.102 (49), p.17834-17839

2005

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Virtual Screening of Transmembrane Serine Protease Inhibitors

Bio-protocol, 2017-04, Vol.7 (8), p.e2246-e2246

2017

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Faulty Epithelial Polarity Genes and Cancer

Advances in Cancer Research, 2011, Vol.111, p.97-161

2011

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Overexpression of a truncated TrkB isoform increases the proliferation of neural progenitors

The European journal of neuroscience, 2006-09, Vol.24 (5), p.1277-1285

2006

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Abstract LB-204: Oncogenic Ras signaling requires serine protease hepsin to induce invasive breast cancer phenotype

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.LB-204-LB-204

2020

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Abstract 5817: LKB1 overcomes RAS pathway-mediated loss of epithelial integrity

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.5817-5817

2023

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Abstract 3484: Ras recruits oncogenic serine protease hepsin to disrupt mammary epithelial integrity

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.3484-3484

2019

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Hepsin regulates TGFβ signaling via fibronectin proteolysis

The FASEB journal, 2021-05, Vol.35 (S1), p.n/a, Article fasebj.2021.35.S1.02255

2021

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Abstract 834: Serine protease hepsin regulates tumor growth via TGFbeta-EGFR signaling axis

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.834-834

2022

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Myc-induced AMPK-phospho p53 pathway activates Bak to sensitize mitochondrial apoptosis

Proceedings of the National Academy of Sciences - PNAS, 2013-05, Vol.110 (20), p.7976-7977

2013

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Rgs4 mRNA expression is decreased in the brain of Fmr1 knockout mouse

Brain research. Molecular brain research., 2005-01, Vol.133 (1), p.162-165

2005

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The Cell-Surface, Transmembrane Serine Protease Hepsin: Discovery, Function and Role in Cancer

Extracellular Targeting of Cell Signaling in Cancer, 2018, p.125-154

2018

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Real-time monitoring of human blood-brain barrier disruption

PloS one, 2017-03, Vol.12 (3), p.e0174072-e0174072

2017

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Myc-induced AMPK-phospho p53 pathway activates Bak to sensitize mitochondrial apoptosis

Immunoglobulin superfamily member 3 is required for the vagal neural crest cell migration and enteric neuronal network organization

Hepsin promotes breast tumor growth signaling via the TGFβ‐EGFR axis

Breaking the epithelial polarity barrier in cancer: the strange case of LKB1/PAR-4

Hepsin regulates TGFβ signaling via fibronectin proteolysis

Oncogenic Ras Disrupts Epithelial Integrity by Activating the Transmembrane Serine Protease Hepsin

Design, Synthesis, and Testing of Potent, Selective Hepsin Inhibitors via Application of an Automated Closed-Loop Optimization Platform

Tumor suppressor function of Liver kinase B1 (Lkb1) is linked to regulation of epithelial integrity

Analyzing the Type II Transmembrane Serine Protease Hepsin-Dependent Basement Membrane Remodeling in 3D Cell Culture

Aberrant differentiation of glutamatergic cells in neocortex of mouse model for fragile X syndrome

Altered Differentiation of Neural Stem Cells in Fragile X Syndrome

Virtual Screening of Transmembrane Serine Protease Inhibitors

Faulty Epithelial Polarity Genes and Cancer

Overexpression of a truncated TrkB isoform increases the proliferation of neural progenitors

Abstract LB-204: Oncogenic Ras signaling requires serine protease hepsin to induce invasive breast cancer phenotype

Abstract 5817: LKB1 overcomes RAS pathway-mediated loss of epithelial integrity

Abstract 3484: Ras recruits oncogenic serine protease hepsin to disrupt mammary epithelial integrity

Hepsin regulates TGFβ signaling via fibronectin proteolysis

Abstract 834: Serine protease hepsin regulates tumor growth via TGFbeta-EGFR signaling axis

Myc-induced AMPK-phospho p53 pathway activates Bak to sensitize mitochondrial apoptosis

Rgs4 mRNA expression is decreased in the brain of Fmr1 knockout mouse

The Cell-Surface, Transmembrane Serine Protease Hepsin: Discovery, Function and Role in Cancer

Real-time monitoring of human blood-brain barrier disruption

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