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A pharmacological rationale for improved everolimus dosing in oncology and transplant patients

British journal of clinical pharmacology, 2018-07, Vol.84 (7), p.1575-1586

2018

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Effects of cytochrome P450 3A (CYP3A) and the drug transporters P‐glycoprotein (MDR1/ABCB1) and MRP2 (ABCC2) on the pharmacokinetics of lopinavir

British journal of pharmacology, 2010-07, Vol.160 (5), p.1224-1233

2010

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Off-label, but on target: the evidence needed to implement alternative dosing regimens of anticancer drugs

ESMO open, 2023-02, Vol.8 (1), p.100749-100749, Article 100749

2023

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Quantification of protease inhibitors and non-nucleoside reverse transcriptase inhibitors in dried blood spots by liquid chromatography–triple quadrupole mass spectrometry

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2008-05, Vol.867 (2), p.205-212

2008

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REducing STEroids in Relapsing Nephrotic syndrome: the RESTERN study— protocol of a national, double-blind, randomised, placebo-controlled, non-inferiority intervention study

BMJ open, 2017-09, Vol.7 (9), p.e018148-e018148

2017

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Quantification of the HIV-integrase inhibitor raltegravir and detection of its main metabolite in human plasma, dried blood spots and peripheral blood mononuclear cell lysate by means of high-performance liquid chromatography tandem mass spectrometry

Journal of pharmaceutical and biomedical analysis, 2009-02, Vol.49 (2), p.451-458

2009

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Development and validation of a bioanalytical assay for the measurement of total and unbound teicoplanin in human serum

Journal of antimicrobial chemotherapy, 2023-11, Vol.78 (11), p.2723-2730

2023

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Bioanalytical issues in patient-friendly sampling methods for therapeutic drug monitoring: focus on antiretroviral drugs

Bioanalysis, 2009-10, Vol.1 (7), p.1329-1338

2009

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Identification and profiling of circulating metabolites of atazanavir, a HIV protease inhibitor

Drug metabolism and disposition, 2009-09, Vol.37 (9), p.1826

2009

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Cumulative pemetrexed dose increases the risk of nephrotoxicity

Lung cancer (Amsterdam, Netherlands), 2020-08, Vol.146, p.30-35

2020

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Penetration of Atazanavir in Seminal Plasma of Men Infected with Human Immunodeficiency Virus Type 1

Antimicrobial Agents and Chemotherapy, 2007-01, Vol.51 (1), p.335-337

2007

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Pharmacokinetics of extended dose intervals of micafungin in haematology patients: optimizing antifungal prophylaxis

Journal of antimicrobial chemotherapy, 2018-11, Vol.73 (11), p.3095-3101

2018

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Perinatal exposure of rats to the HIV drug efavirenz affects medial prefrontal cortex cytoarchitecture

Biochemical pharmacology, 2020-08, Vol.178, p.114050, Article 114050

2020

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Pharmacokinetically-guided dosing of pemetrexed in a patient with renal impairment and a patient requiring hemodialysis

Lung cancer (Amsterdam, Netherlands), 2019-04, Vol.130, p.156-158

2019

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Towards better dose individualisation: metabolic phenotyping to predict cabazitaxel pharmacokinetics in men with prostate cancer

British journal of cancer, 2017-05, Vol.116 (10), p.1312-1317

2017

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Therapeutic Exposure and Successful Response to Pembrolizumab in a Patient With Non–Small-Cell Lung Cancer Despite Significant Renal Loss Due to Paraneoplastic Nephrotic Syndrome

Clinical lung cancer, 2021-03, Vol.22 (2), p.e220-e223

2021

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Chloroquine for treatment of COVID-19 results in subtherapeutic exposure and prolonged QTc intervals

International journal of antimicrobial agents, 2021-03, Vol.57 (3), p.106293-106293, Article 106293

2021

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Drug composition matters: the influence of carrier concentration on the radiochemical purity, hydroxyapatite affinity and in-vivo bone accumulation of the therapeutic radiopharmaceutical 188Rhenium-HEDP

Nuclear medicine and biology, 2015-05, Vol.42 (5), p.465-469

2015

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Quantification of etravirine (TMC125) in plasma, dried blood spots and peripheral blood mononuclear cell lysate by liquid chromatography tandem mass spectrometry

Journal of pharmaceutical and biomedical analysis, 2009-02, Vol.49 (2), p.393-400

2009

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Metastatic Prostate Cancer and Skeletal Related Events, a Cost of Illness Study

Value in health, 2014-11, Vol.17 (7), p.A626-A626

2014

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Fatal interstitial lung disease associated with high erlotinib and metabolite levels. A case report and a review of the literature

Lung cancer (Amsterdam, Netherlands), 2012-03, Vol.75 (3), p.391-397

2012

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Quantification of HIV protease inhibitors and non-nucleoside reverse transcriptase inhibitors in peripheral blood mononuclear cell lysate using liquid chromatography coupled with tandem mass spectrometry

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2009-02, Vol.877 (5), p.575-580

2009

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EP08.02-090 Sotorasib Drug-Drug Interactions: Essential Guidance Requested by Physicians Worldwide

Journal of thoracic oncology, 2022-09, Vol.17 (9), p.S444-S445

2022

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769P Pharmacokinetic boosting of olaparib: An open-label, prospective, cross-over study

Annals of oncology, 2023-10, Vol.34, p.S522-S522

2023

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Tumor drug exposure is positively correlated with an improved outcome, in patients with advanced solid tumors, upon treatment with a high dose intermittent sunitinib regimen

European journal of cancer (1990), 2020-10, Vol.138, p.S19-S19

2020

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A pharmacological rationale for improved everolimus dosing in oncology and transplant patients

Effects of cytochrome P450 3A (CYP3A) and the drug transporters P‐glycoprotein (MDR1/ABCB1) and MRP2 (ABCC2) on the pharmacokinetics of lopinavir

Off-label, but on target: the evidence needed to implement alternative dosing regimens of anticancer drugs

Quantification of protease inhibitors and non-nucleoside reverse transcriptase inhibitors in dried blood spots by liquid chromatography–triple quadrupole mass spectrometry

REducing STEroids in Relapsing Nephrotic syndrome: the RESTERN study— protocol of a national, double-blind, randomised, placebo-controlled, non-inferiority intervention study

Quantification of the HIV-integrase inhibitor raltegravir and detection of its main metabolite in human plasma, dried blood spots and peripheral blood mononuclear cell lysate by means of high-performance liquid chromatography tandem mass spectrometry

Development and validation of a bioanalytical assay for the measurement of total and unbound teicoplanin in human serum

Bioanalytical issues in patient-friendly sampling methods for therapeutic drug monitoring: focus on antiretroviral drugs

Identification and profiling of circulating metabolites of atazanavir, a HIV protease inhibitor

Cumulative pemetrexed dose increases the risk of nephrotoxicity

Penetration of Atazanavir in Seminal Plasma of Men Infected with Human Immunodeficiency Virus Type 1

Pharmacokinetics of extended dose intervals of micafungin in haematology patients: optimizing antifungal prophylaxis

Perinatal exposure of rats to the HIV drug efavirenz affects medial prefrontal cortex cytoarchitecture

Pharmacokinetically-guided dosing of pemetrexed in a patient with renal impairment and a patient requiring hemodialysis

Towards better dose individualisation: metabolic phenotyping to predict cabazitaxel pharmacokinetics in men with prostate cancer

Therapeutic Exposure and Successful Response to Pembrolizumab in a Patient With Non–Small-Cell Lung Cancer Despite Significant Renal Loss Due to Paraneoplastic Nephrotic Syndrome

Chloroquine for treatment of COVID-19 results in subtherapeutic exposure and prolonged QTc intervals

Drug composition matters: the influence of carrier concentration on the radiochemical purity, hydroxyapatite affinity and in-vivo bone accumulation of the therapeutic radiopharmaceutical 188Rhenium-HEDP

Quantification of etravirine (TMC125) in plasma, dried blood spots and peripheral blood mononuclear cell lysate by liquid chromatography tandem mass spectrometry

Metastatic Prostate Cancer and Skeletal Related Events, a Cost of Illness Study

Fatal interstitial lung disease associated with high erlotinib and metabolite levels. A case report and a review of the literature

Quantification of HIV protease inhibitors and non-nucleoside reverse transcriptase inhibitors in peripheral blood mononuclear cell lysate using liquid chromatography coupled with tandem mass spectrometry

EP08.02-090 Sotorasib Drug-Drug Interactions: Essential Guidance Requested by Physicians Worldwide

769P Pharmacokinetic boosting of olaparib: An open-label, prospective, cross-over study

Tumor drug exposure is positively correlated with an improved outcome, in patients with advanced solid tumors, upon treatment with a high dose intermittent sunitinib regimen

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