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A Novel PDE10A Inhibitor for Tourette Syndrome and Other Movement Disorders

Cells (Basel, Switzerland), 2024-07, Vol.13 (14), p.1230

2024

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Ultrapure ajulemic acid has improved CB2 selectivity with reduced CB1 activity

Bioorganic & medicinal chemistry, 2014-07, Vol.22 (13), p.3245-3251

2014

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Anti-inflammatory effects of lenabasum, a cannabinoid receptor type 2 agonist, on macrophages from cystic fibrosis

Journal of cystic fibrosis, 2020-09, Vol.19 (5), p.823-829

2020

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In vitro metabolism and metabolic effects of ajulemic acid, a synthetic cannabinoid agonist

Pharmacology research & perspectives, 2013-12, Vol.1 (2), p.e00017-n/a

2013

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A Single Receptor Binds Both Insulin-Like Growth Factor II and Mannose-6-Phosphate

Science (American Association for the Advancement of Science), 1988-03, Vol.239 (4844), p.1134-1137

1988

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Immunosuppression in Vivo by a Soluble Form of the CTLA-4 T Cell Activation Molecule

Science (American Association for the Advancement of Science), 1992-08, Vol.257 (5071), p.792-795

1992

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Interaction of the Immunosuppressant Deoxyspergualin with a Member of the Hsp70 Family of Heat Shock Proteins

Science (American Association for the Advancement of Science), 1992-10, Vol.258 (5081), p.484-486

1992

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Formation of human IFN-beta complex with the soluble type I interferon receptor IFNAR-2 leads to enhanced IFN stability, pharmacokinetics, and antitumor activity in xenografted SCID mice

Journal of interferon & cytokine research, 2004-02, Vol.24 (2), p.119-129

2004

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Quantitation of the Interaction of the Immunosuppressant Deoxyspergualin and Analogs with Hsc70 and Hsp90

Biochemistry (Easton), 1994-03, Vol.33 (9), p.2561-2567

1994

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Prevention of Immunotoxin-Mediated Vascular Leak Syndrome in Rats with Retention of Antitumor Activity

Proceedings of the National Academy of Sciences - PNAS, 1994-09, Vol.91 (20), p.9514-9518

1994

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The neutralization of type I IFN biologic actions by anti-IFNAR-2 monoclonal antibodies is not entirely due to inhibition of Jak-Stat tyrosine phosphorylation

Journal of interferon & cytokine research, 2000-11, Vol.20 (11), p.971-982

2000

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Elucidating the mechanism of action of the immunosuppressant 15-deoxyspergualin

Therapeutic drug monitoring, 1995-12, Vol.17 (6), p.700-703

1995

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Soluble human lymphocyte activation gene-3 modulates allospecific T cell responses

International immunology, 1998-05, Vol.10 (5), p.679-689

1998

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Phase I clinical and pharmacological study of suppression of human antimouse antibody response to monoclonal antibody L6 by deoxyspergualin

Cancer research (Chicago, Ill.), 1995-07, Vol.55 (14), p.3060-3067

1995

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Deoxyspergualin inhibits kappa light chain expression in 70Z/3 pre-B cells by blocking lipopolysaccharide-induced NF-kappa B activation

The Journal of immunology (1950), 1995-09, Vol.155 (5), p.2427-2436

1995

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Deoxyspergualin

Annals of the New York Academy of Sciences, 1993-11, Vol.696 (1), p.123-132

TEPPER, MARK A.

1993

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Immunosuppressant deoxyspergualin inhibits antigen processing in monocytes

The Journal of immunology (1950), 1994-11, Vol.153 (9), p.3908-3916

1994

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Deoxyspergualin. Mechanism of action studies of a novel immunosuppressive drug

Annals of the New York Academy of Sciences, 1993-11, Vol.696 (1), p.123-132

Tepper, M A

1993

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Specific binding of Fyn and phosphatidylinositol 3‐kinase to the B cell surface glycoprotein CD19 through their src homology 2 domains

European journal of immunology, 1995-10, Vol.25 (10), p.2978-2984

1995

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15-Deoxyspergualin: A Novel Immunosuppressive Drug with Clinical Potential

Annals of the New York Academy of Sciences, 1993-06, Vol.685 (1), p.175-192

1993

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Evidence for only one β-luteinizing hormone and no β-chorionic gonadotropin gene in the rat

Endocrinology (Philadelphia), 1984-07, Vol.115 (1), p.385-391

1984

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15-Deoxyspergualin, a Novel Immunosuppressive Drug: Studies of the Mechanism of Action

Annals of the New York Academy of Sciences, 1993-06, Vol.685 (1), p.136-147

1993

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Effects of 15-Deoxyspergualin on the Expression of Surface Immunoglobulin in 70Z/3.12 Murine Pre-B Cell Line

Annals of the New York Academy of Sciences, 1993-06, Vol.685 (1), p.205-206

1993

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Prevention of the humoral response induced by an anti-CD3 monoclonal antibody by deoxyspergualin in a murine model

Transplantation, 1994-06, Vol.57 (12), p.1786

1994

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Studies on the Interaction of the Immunosuppressant 15-Deoxyspergualin with Heat Shock Proteins

Annals of the New York Academy of Sciences, 1993-11, Vol.696 (1), p.412-414

1993

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A Novel PDE10A Inhibitor for Tourette Syndrome and Other Movement Disorders

Ultrapure ajulemic acid has improved CB2 selectivity with reduced CB1 activity

Anti-inflammatory effects of lenabasum, a cannabinoid receptor type 2 agonist, on macrophages from cystic fibrosis

In vitro metabolism and metabolic effects of ajulemic acid, a synthetic cannabinoid agonist

A Single Receptor Binds Both Insulin-Like Growth Factor II and Mannose-6-Phosphate

Immunosuppression in Vivo by a Soluble Form of the CTLA-4 T Cell Activation Molecule

Interaction of the Immunosuppressant Deoxyspergualin with a Member of the Hsp70 Family of Heat Shock Proteins

Formation of human IFN-beta complex with the soluble type I interferon receptor IFNAR-2 leads to enhanced IFN stability, pharmacokinetics, and antitumor activity in xenografted SCID mice

Quantitation of the Interaction of the Immunosuppressant Deoxyspergualin and Analogs with Hsc70 and Hsp90

Prevention of Immunotoxin-Mediated Vascular Leak Syndrome in Rats with Retention of Antitumor Activity

The neutralization of type I IFN biologic actions by anti-IFNAR-2 monoclonal antibodies is not entirely due to inhibition of Jak-Stat tyrosine phosphorylation

Elucidating the mechanism of action of the immunosuppressant 15-deoxyspergualin

Soluble human lymphocyte activation gene-3 modulates allospecific T cell responses

Phase I clinical and pharmacological study of suppression of human antimouse antibody response to monoclonal antibody L6 by deoxyspergualin

Deoxyspergualin inhibits kappa light chain expression in 70Z/3 pre-B cells by blocking lipopolysaccharide-induced NF-kappa B activation

Deoxyspergualin

Immunosuppressant deoxyspergualin inhibits antigen processing in monocytes

Deoxyspergualin. Mechanism of action studies of a novel immunosuppressive drug

Specific binding of Fyn and phosphatidylinositol 3‐kinase to the B cell surface glycoprotein CD19 through their src homology 2 domains

15-Deoxyspergualin: A Novel Immunosuppressive Drug with Clinical Potential

Evidence for only one β-luteinizing hormone and no β-chorionic gonadotropin gene in the rat

15-Deoxyspergualin, a Novel Immunosuppressive Drug: Studies of the Mechanism of Action

Effects of 15-Deoxyspergualin on the Expression of Surface Immunoglobulin in 70Z/3.12 Murine Pre-B Cell Line

Prevention of the humoral response induced by an anti-CD3 monoclonal antibody by deoxyspergualin in a murine model

Studies on the Interaction of the Immunosuppressant 15-Deoxyspergualin with Heat Shock Proteins

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