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Proteasome Activation as a New Therapeutic Approach To Target Proteotoxic Disorders

Journal of medicinal chemistry, 2019-07, Vol.62 (14), p.6469-6481

2019

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Accessing Highly Oxidized Imidazolidinone Cores via a Curtius Rearrangement: Total Synthesis of Colensolide A

Organic letters, 2023-05, Vol.25 (20), p.3698-3701

2023

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Proteasome Activation to Combat Proteotoxicity

Molecules (Basel, Switzerland), 2019-08, Vol.24 (15), p.2841

2019

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Synthesis, structure, properties, and cytotoxicity of a (quinoline)RuCp complex

Dalton transactions : an international journal of inorganic chemistry, 2023-01, Vol.52 (3), p.721-73

2023

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Advances in Proteasome Enhancement by Small Molecules

Biomolecules (Basel, Switzerland), 2021-11, Vol.11 (12), p.1789

2021

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20S proteasome enhancers prevent cytotoxic tubulin polymerization-promoting protein induced α-synuclein aggregation

iScience, 2024-07, Vol.27 (7), p.110166, Article 110166

2024

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Substrate Controlled Regioselective Bromination of Acylated Pyrroles Using Tetrabutylammonium Tribromide (TBABr3)

Journal of organic chemistry, 2018-08, Vol.83 (16), p.9250-9255

2018

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Perspectives on SARS-CoV‑2 Main Protease Inhibitors

Journal of medicinal chemistry, 2021-12, Vol.64 (23), p.16922-16955

2021

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Indolo-Phakellins as β5-Specific Noncovalent Proteasome Inhibitors

Angewandte Chemie (International ed.), 2015-02, Vol.54 (9), p.2830-2833

2015

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One-Pot Friedel–Crafts/Robinson–Gabriel Synthesis of the Indole-Oxazole Scaffold and Its Application to the Synthesis of Breitfussins C, G, and H

Journal of organic chemistry, 2023-01, Vol.88 (2), p.755-761

2023

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Regulation of Autophagic Flux by the 20S Proteasome

Cell chemical biology, 2019-09, Vol.26 (9), p.1283-1294.e5

2019

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Sc(OTf)3‑Mediated One-Pot Synthesis of 2,3-Disubstituted Quinolines from Anilines and Epoxides

Journal of organic chemistry, 2020-05, Vol.85 (10), p.6741-6746

2020

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Advances in the total synthesis of bis- and tris-indole alkaloids containing N-heterocyclic linker moieties

Natural product reports, 2024-04

2024

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Total Synthesis of Nagelamide W

Journal of organic chemistry, 2023-07, Vol.88 (13), p.9306-9312

2023

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Total Synthesis of Nortopsentin D via a Late-Stage Pinacol-like Rearrangement

Organic letters, 2021-07, Vol.23 (14), p.5368-5372

2021

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Sc(OTf) 3 -Mediated One-Pot Synthesis of 3,4-Disubstituted 1 H -Pyrazoles and 3,5-Disubstituted Pyridines from Hydrazine or Ammonia with Epoxides

Journal of organic chemistry, 2022-12, Vol.87 (24), p.16820-16828

2022

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Rh(III)-Catalyzed C–H Activation/Annulation of Benzohydroxamates and 2‑Imidazolones: Access to Urea-Fused-Dihydroisoquinolone Scaffolds Reminiscent of Pyrrole Alkaloid Natural Products

Organic letters, 2022-09, Vol.24 (37), p.6740-6744

2022

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Palau’amine and Related Oroidin Alkaloids Dibromophakellin and Dibromophakellstatin Inhibit the Human 20S Proteasome

Journal of natural products (Washington, D.C.), 2012-05, Vol.75 (5), p.980-985

2012

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Recent Advances in the Synthesis of Imidazolines (2009–2020)

Advanced synthesis & catalysis, 2020-10, Vol.362 (20), p.4189-4225

2020

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Diastereoselective One-Pot Synthesis of Oxazolines Using Sulfur Ylides and Acyl Imines

Journal of organic chemistry, 2019-06, Vol.84 (11), p.7219-7226

2019

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Small Molecule Modulation of Proteasome Assembly

Biochemistry (Easton), 2018-07, Vol.57 (28), p.4214-4224

2018

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Design, Synthesis, and Biological Evaluation of Potent 20S Proteasome Activators for the Potential Treatment of α‑Synucleinopathies

Journal of medicinal chemistry, 2022-05, Vol.65 (9), p.6631-6642

2022

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Sc(OTf)3‑Mediated One-Pot Synthesis of 3,4-Disubstituted 1H‑Pyrazoles and 3,5-Disubstituted Pyridines from Hydrazine or Ammonia with Epoxides

Journal of organic chemistry, 2022-12, Vol.87 (24), p.16820-16828

2022

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Radioprotection by Hymenialdisine-Derived Checkpoint Kinase 2 Inhibitors

ACS chemical biology, 2012-01, Vol.7 (1), p.172-184

2012

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Intermolecular Ene Reactions Utilizing Oxazolones and Enol Ethers

Journal of the American Chemical Society, 2007-03, Vol.129 (11), p.3058-3059

2007

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Proteasome Activation as a New Therapeutic Approach To Target Proteotoxic Disorders

Accessing Highly Oxidized Imidazolidinone Cores via a Curtius Rearrangement: Total Synthesis of Colensolide A

Proteasome Activation to Combat Proteotoxicity

Synthesis, structure, properties, and cytotoxicity of a (quinoline)RuCp complex

Advances in Proteasome Enhancement by Small Molecules

20S proteasome enhancers prevent cytotoxic tubulin polymerization-promoting protein induced α-synuclein aggregation

Substrate Controlled Regioselective Bromination of Acylated Pyrroles Using Tetrabutylammonium Tribromide (TBABr3)

Perspectives on SARS-CoV‑2 Main Protease Inhibitors

Indolo-Phakellins as β5-Specific Noncovalent Proteasome Inhibitors

One-Pot Friedel–Crafts/Robinson–Gabriel Synthesis of the Indole-Oxazole Scaffold and Its Application to the Synthesis of Breitfussins C, G, and H

Regulation of Autophagic Flux by the 20S Proteasome

Sc(OTf)3‑Mediated One-Pot Synthesis of 2,3-Disubstituted Quinolines from Anilines and Epoxides

Advances in the total synthesis of bis- and tris-indole alkaloids containing N-heterocyclic linker moieties

Total Synthesis of Nagelamide W

Total Synthesis of Nortopsentin D via a Late-Stage Pinacol-like Rearrangement

Sc(OTf) 3 -Mediated One-Pot Synthesis of 3,4-Disubstituted 1 H -Pyrazoles and 3,5-Disubstituted Pyridines from Hydrazine or Ammonia with Epoxides

Rh(III)-Catalyzed C–H Activation/Annulation of Benzohydroxamates and 2‑Imidazolones: Access to Urea-Fused-Dihydroisoquinolone Scaffolds Reminiscent of Pyrrole Alkaloid Natural Products

Palau’amine and Related Oroidin Alkaloids Dibromophakellin and Dibromophakellstatin Inhibit the Human 20S Proteasome

Recent Advances in the Synthesis of Imidazolines (2009–2020)

Diastereoselective One-Pot Synthesis of Oxazolines Using Sulfur Ylides and Acyl Imines

Small Molecule Modulation of Proteasome Assembly

Design, Synthesis, and Biological Evaluation of Potent 20S Proteasome Activators for the Potential Treatment of α‑Synucleinopathies

Sc(OTf)3‑Mediated One-Pot Synthesis of 3,4-Disubstituted 1H‑Pyrazoles and 3,5-Disubstituted Pyridines from Hydrazine or Ammonia with Epoxides

Radioprotection by Hymenialdisine-Derived Checkpoint Kinase 2 Inhibitors

Intermolecular Ene Reactions Utilizing Oxazolones and Enol Ethers

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