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Surface Comparison of Active and Inactive Protein Kinases Identifies a Conserved Activation Mechanism

Proceedings of the National Academy of Sciences - PNAS, 2006-11, Vol.103 (47), p.17783-17788

2006

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helix scaffold for the assembly of active protein kinases

Proceedings of the National Academy of Sciences - PNAS, 2008-09, Vol.105 (38), p.14377-14382

2008

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Identification and Characterization of EX1 Kinetics in H/D Exchange Mass Spectrometry by Peak Width Analysis

Journal of the American Society for Mass Spectrometry, 2006-11, Vol.17 (11), p.1498-1509

2006

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Computational Reconstruction of Multidomain Proteins Using Atomic Force Microscopy Data

Structure (London), 2012-01, Vol.20 (1), p.113-120

2012

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Vaccinia Virus Immunomodulator A46: A Lipid and Protein-Binding Scaffold for Sequestering Host TIR-Domain Proteins

PLoS pathogens, 2016-12, Vol.12 (12), p.e1006079-e1006079

2016

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The cAMP Binding Domain: An Ancient Signaling Module

Proceedings of the National Academy of Sciences - PNAS, 2005-01, Vol.102 (1), p.45-50

2005

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A generalized allosteric mechanism for cis-regulated cyclic nucleotide binding domains

PLoS computational biology, 2008-04, Vol.4 (4), p.e1000056-e1000056

2008

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Functional and structural characterization of a thermostable acetyl esterase from Thermotoga maritima

Proteins, structure, function, and bioinformatics, 2012-06, Vol.80 (6), p.1545-1559

2012

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From structure to the dynamic regulation of a molecular switch: A journey over 3 decades

The Journal of biological chemistry, 2021-01, Vol.296, p.100746-100746, Article 100746

2021

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Protein docking using continuum electrostatics and geometric fit

Protein engineering, 2001-02, Vol.14 (2), p.105-113

2001

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Conserved spatial patterns across the protein kinase family

Biochimica et biophysica acta, 2008, Vol.1784 (1), p.238-243

2008

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Crystal Structure of the Catalytic Subunit of Cyclic Adenosine Monophosphate-Dependent Protein Kinase

Science (American Association for the Advancement of Science), 1991-07, Vol.253 (5018), p.407-414

1991

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Structure of a Peptide Inhibitor Bound to the Catalytic Subunit of Cyclic Adenosine Monophosphate-Dependent Protein Kinase

Science (American Association for the Advancement of Science), 1991-07, Vol.253 (5018), p.414-420

1991

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Constitutive Activation of Extracellular Signal-regulated Kinase 2 by Synergistic Point Mutations

The Journal of biological chemistry, 2001-12, Vol.276 (49), p.46469-46479

2001

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Predicting protein-DNA interactions by full search computational docking

Proteins, structure, function, and bioinformatics, 2013-12, Vol.81 (12), p.2106-2118

2013

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A binary complex of the catalytic subunit of cAMP-dependent protein kinase and adenosine further defines conformational flexibility

Structure (London), 1997-07, Vol.5 (7), p.921-935

1997

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Comparative surface geometry of the protein kinase family

Protein science, 2009-10, Vol.18 (10), p.2016-2026

2009

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Combining H/D exchange mass spectroscopy and computational docking reveals extended DNA-binding surface on uracil-DNA glycosylase

Nucleic acids research, 2012-07, Vol.40 (13), p.6070-6081

2012

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Dynamic Features of cAMP-dependent Protein Kinase Revealed by Apoenzyme Crystal Structure

Journal of molecular biology, 2003-03, Vol.327 (1), p.159-171

2003

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Rapid Estimation of Solvation Energy for Simulations of Protein−Protein Association

Journal of chemical theory and computation, 2005-01, Vol.1 (1), p.143-152

2005

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Automated extraction of backbone deuteration levels from amide H/2H mass spectrometry experiments

Protein science, 2006-03, Vol.15 (3), p.583-601

2006

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Crystal Structures of RIα Subunit of Cyclic Adenosine 5‘-Monophosphate (cAMP)-Dependent Protein Kinase Complexed with (R p)-Adenosine 3‘,5‘-Cyclic Monophosphothioate and (S p)-Adenosine 3‘,5‘-Cyclic Monophosphothioate, the Phosphothioate Analogues of cAMP

Biochemistry (Easton), 2004-06, Vol.43 (21), p.6620-6629

2004

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A Conserved Helix Motif Complements the Protein Kinase Core

Proceedings of the National Academy of Sciences - PNAS, 1993-11, Vol.90 (22), p.10618-10622

1993

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Structural Basis of the Intrasteric Regulation of Myosin Light Chain Kinases

Science (American Association for the Advancement of Science), 1992-10, Vol.258 (5079), p.130-135

1992

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Structural Features that Specify Tyrosine Kinase Activity Deduced from Homology Modeling of the Epidermal Growth Factor Receptor

Proceedings of the National Academy of Sciences - PNAS, 1993-06, Vol.90 (11), p.5001-5005

1993

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Surface Comparison of Active and Inactive Protein Kinases Identifies a Conserved Activation Mechanism

helix scaffold for the assembly of active protein kinases

Identification and Characterization of EX1 Kinetics in H/D Exchange Mass Spectrometry by Peak Width Analysis

Computational Reconstruction of Multidomain Proteins Using Atomic Force Microscopy Data

Vaccinia Virus Immunomodulator A46: A Lipid and Protein-Binding Scaffold for Sequestering Host TIR-Domain Proteins

The cAMP Binding Domain: An Ancient Signaling Module

A generalized allosteric mechanism for cis-regulated cyclic nucleotide binding domains

Functional and structural characterization of a thermostable acetyl esterase from Thermotoga maritima

From structure to the dynamic regulation of a molecular switch: A journey over 3 decades

Protein docking using continuum electrostatics and geometric fit

Conserved spatial patterns across the protein kinase family

Crystal Structure of the Catalytic Subunit of Cyclic Adenosine Monophosphate-Dependent Protein Kinase

Structure of a Peptide Inhibitor Bound to the Catalytic Subunit of Cyclic Adenosine Monophosphate-Dependent Protein Kinase

Constitutive Activation of Extracellular Signal-regulated Kinase 2 by Synergistic Point Mutations

Predicting protein-DNA interactions by full search computational docking

A binary complex of the catalytic subunit of cAMP-dependent protein kinase and adenosine further defines conformational flexibility

Comparative surface geometry of the protein kinase family

Combining H/D exchange mass spectroscopy and computational docking reveals extended DNA-binding surface on uracil-DNA glycosylase

Dynamic Features of cAMP-dependent Protein Kinase Revealed by Apoenzyme Crystal Structure

Rapid Estimation of Solvation Energy for Simulations of Protein−Protein Association

Automated extraction of backbone deuteration levels from amide H/2H mass spectrometry experiments

Crystal Structures of RIα Subunit of Cyclic Adenosine 5‘-Monophosphate (cAMP)-Dependent Protein Kinase Complexed with (R p)-Adenosine 3‘,5‘-Cyclic Monophosphothioate and (S p)-Adenosine 3‘,5‘-Cyclic Monophosphothioate, the Phosphothioate Analogues of cAMP

A Conserved Helix Motif Complements the Protein Kinase Core

Structural Basis of the Intrasteric Regulation of Myosin Light Chain Kinases

Structural Features that Specify Tyrosine Kinase Activity Deduced from Homology Modeling of the Epidermal Growth Factor Receptor

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