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CDK2 inhibitors as candidate therapeutics for cisplatin- and noise-induced hearing loss

The Journal of experimental medicine, 2018-04, Vol.215 (4), p.1187-1203

2018

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Dync1li1 is required for the survival of mammalian cochlear hair cells by regulating the transportation of autophagosomes

PLoS genetics, 2022-06, Vol.18 (6), p.e1010232-e1010232

2022

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ERK1/2 Inhibition via the Oral Administration of Tizaterkib Alleviates Noise-Induced Hearing Loss While Tempering down the Immune Response

International journal of molecular sciences, 2024-06, Vol.25 (12), p.6305

2024

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Common variants in ACYP2 influence susceptibility to cisplatin-induced hearing loss

Nature genetics, 2015-03, Vol.47 (3), p.263-266

2015

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Trametinib, a MEK1/2 Inhibitor, Protects Mice from Cisplatin- and Noise-Induced Hearing Loss

Pharmaceuticals (Basel, Switzerland), 2024-06, Vol.17 (6), p.735

2024

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Potentiation of neuroblastoma metastasis by loss of caspase-8

Nature, 2006-01, Vol.439 (7072), p.95-99

2006

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Oseltamivir (Tamiflu), a commonly prescribed antiviral drug, mitigates hearing loss in mice

Clinical and translational medicine, 2024-08, Vol.14 (8), p.e1803-n/a

2024

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Preclinical models for neuroblastoma: establishing a baseline for treatment

PloS one, 2011-04, Vol.6 (4), p.e19133-e19133

2011

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Allelic imbalance on chromosome 2q and alterations of the caspase 8 gene in neuroblastoma

Oncogene, 2001-07, Vol.20 (32), p.4424-4432

2001

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KSR1 Knockout Mouse Model Demonstrates MAPK Pathway's Key Role in Cisplatin- and Noise-induced Hearing Loss

The Journal of neuroscience, 2024-05, Vol.44 (18), p.e2174232024

2024

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Repurposing AZD5438 and Dabrafenib for Cisplatin-Induced AKI

Journal of the American Society of Nephrology, 2024-01, Vol.35 (1), p.22-40

2024

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Halting Neuroblastoma Metastasis by Controlling Integrin-Mediated Death

Cell cycle (Georgetown, Tex.), 2006-04, Vol.5 (7), p.681-685

2006

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Caspase-9 and Apaf-1 are expressed and functionally active in human neuroblastoma tumor cell lines with 1p36 LOH and amplified MYCN

Oncogene, 2002-03, Vol.21 (12), p.1848-1858

2002

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Development of Cell-Based High-Throughput Chemical Screens for Protection Against Cisplatin-Induced Ototoxicity

Methods in molecular biology (Clifton, N.J.), 2016, Vol.1427, p.419

2016

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Development of Second-Generation CDK2 Inhibitors for the Prevention of Cisplatin-Induced Hearing Loss

Journal of medicinal chemistry, 2018-09, Vol.61 (17), p.7700-7709

2018

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Caspase-8 Association with the Focal Adhesion Complex Promotes Tumor Cell Migration and Metastasis

Cancer research (Chicago, Ill.), 2009-05, Vol.69 (9), p.3755-3763

2009

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Th-MYCN Mice with Caspase-8 Deficiency Develop Advanced Neuroblastoma with Bone Marrow Metastasis

Cancer research (Chicago, Ill.), 2013-07, Vol.73 (13), p.4086-4097

2013

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BRAF inhibition protects against hearing loss in mice

Science advances, 2020-12, Vol.6 (49)

2020

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Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN

Nature medicine, 2000-05, Vol.6 (5), p.529-535

2000

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Dabrafenib protects from cisplatin-induced hearing loss in a clinically relevant mouse model

JCI insight, 2023-12, Vol.8 (24)

2023

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Corrigendum: Common variants in ACYP2 influence susceptibility to cisplatin-induced hearing loss

Nature genetics, 2015-04, Vol.47 (4), p.423-423

2015

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Erratum: Corrigendum: Common variants in ACYP2 influence susceptibility to cisplatin-induced hearing loss

Nature genetics, 2015-03, Vol.47 (4), p.423-423

2015

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Aggressive childhood neuroblastomas do not express caspase-8 : an important component of programmed cell death

Journal of molecular medicine (Berlin, Germany), 2001-08, Vol.79 (8), p.428-436

2001

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Does integrin-mediated cell death confer tissue tropism in metastasis?

Cancer research (Chicago, Ill.), 2006-06, Vol.66 (12), p.5981-5984

2006

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Proteolytic regulation of apoptosis

Seminars in cell & developmental biology, 2000-06, Vol.11 (3), p.191-201

2000

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CDK2 inhibitors as candidate therapeutics for cisplatin- and noise-induced hearing loss

Dync1li1 is required for the survival of mammalian cochlear hair cells by regulating the transportation of autophagosomes

ERK1/2 Inhibition via the Oral Administration of Tizaterkib Alleviates Noise-Induced Hearing Loss While Tempering down the Immune Response

Common variants in ACYP2 influence susceptibility to cisplatin-induced hearing loss

Trametinib, a MEK1/2 Inhibitor, Protects Mice from Cisplatin- and Noise-Induced Hearing Loss

Potentiation of neuroblastoma metastasis by loss of caspase-8

Oseltamivir (Tamiflu), a commonly prescribed antiviral drug, mitigates hearing loss in mice

Preclinical models for neuroblastoma: establishing a baseline for treatment

Allelic imbalance on chromosome 2q and alterations of the caspase 8 gene in neuroblastoma

KSR1 Knockout Mouse Model Demonstrates MAPK Pathway's Key Role in Cisplatin- and Noise-induced Hearing Loss

Repurposing AZD5438 and Dabrafenib for Cisplatin-Induced AKI

Halting Neuroblastoma Metastasis by Controlling Integrin-Mediated Death

Caspase-9 and Apaf-1 are expressed and functionally active in human neuroblastoma tumor cell lines with 1p36 LOH and amplified MYCN

Development of Cell-Based High-Throughput Chemical Screens for Protection Against Cisplatin-Induced Ototoxicity

Development of Second-Generation CDK2 Inhibitors for the Prevention of Cisplatin-Induced Hearing Loss

Caspase-8 Association with the Focal Adhesion Complex Promotes Tumor Cell Migration and Metastasis

Th-MYCN Mice with Caspase-8 Deficiency Develop Advanced Neuroblastoma with Bone Marrow Metastasis

BRAF inhibition protects against hearing loss in mice

Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN

Dabrafenib protects from cisplatin-induced hearing loss in a clinically relevant mouse model

Corrigendum: Common variants in ACYP2 influence susceptibility to cisplatin-induced hearing loss

Erratum: Corrigendum: Common variants in ACYP2 influence susceptibility to cisplatin-induced hearing loss

Aggressive childhood neuroblastomas do not express caspase-8 : an important component of programmed cell death

Does integrin-mediated cell death confer tissue tropism in metastasis?

Proteolytic regulation of apoptosis

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