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Structural Analysis of Hen Egg Lysozyme Refolded after Denaturation at Acidic pH

The Protein Journal, 2022-02, Vol.41 (1), p.71-78

2022

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Selective inhibition of the kinase DYRK1A by targeting its folding process

Nature communications, 2016-04, Vol.7 (1), p.11391-14, Article 11391

2016

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Energetics and kinetics of substrate analog-coupled staphylococcal nuclease folding revealed by a statistical mechanical approach

Proceedings of the National Academy of Sciences - PNAS, 2020-08, Vol.117 (33), p.19953-19962

2020

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An Overlapping Region between the Two Terminal Folding Units of the Outer Surface Protein A (OspA) Controls Its Folding Behavior

Journal of molecular biology, 2018-06, Vol.430 (12), p.1799-1813

2018

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Development of novel lithocholic acid derivatives as vitamin D receptor agonists

Bioorganic & medicinal chemistry, 2019-08, Vol.27 (16), p.3674-3681

2019

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Crystal Structures and Thermodynamic Analysis Reveal Distinct Mechanisms of CD28 Phosphopeptide Binding to the Src Homology 2 (SH2) Domains of Three Adaptor Proteins

The Journal of biological chemistry, 2017-01, Vol.292 (3), p.1052-1060

2017

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Crystal structures of complexes of vitamin D receptor ligand-binding domain with lithocholic acid derivatives

Journal of lipid research, 2013-08, Vol.54 (8), p.2206-2213

2013

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The trans isomer of Tau peptide is prone to aggregate, and the WW domain of Pin1 drastically decreases its aggregation

FEBS letters, 2018-09, Vol.592 (18), p.3082-3091

2018

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Mutational effects of Cys113 on structural dynamics of Pin1

Biophysics and Physicobiology, 2019, Vol.16, pp.452-465

2019

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HMGB1 signaling phosphorylates Ku70 and impairs DNA damage repair in Alzheimer's disease pathology

Communications biology, 2021-10, Vol.4 (1), p.1175-1175, Article 1175

2021

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Requirements for peptidyl‐prolyl isomerization activity: A comprehensive mutational analysis of the substrate‐binding cavity of FK506‐binding protein 12

Protein science, 2007-12, Vol.16 (12), p.2618-2625

2007

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Creation of Cross-Linked Crystals With Intermolecular Disulfide Bonds Connecting Symmetry-Related Molecules Allows Retention of Tertiary Structure in Different Solvent Conditions

Frontiers in molecular biosciences, 2022-06, Vol.9, p.908394-908394

2022

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High resolution crystal structure of the Grb2 SH2 domain with a phosphopeptide derived from CD28

PloS one, 2013-09, Vol.8 (9), p.e74482-e74482

2013

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Fine tuning of agonistic/antagonistic activity for vitamin D receptor by 22-alkyl chain length of ligands: 22S-Hexyl compound unexpectedly restored agonistic activity

Bioorganic & medicinal chemistry, 2015-11, Vol.23 (22), p.7274-7281

2015

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Synthesis, Biological Activities, and X‑ray Crystal Structural Analysis of 25-Hydroxy-25(or 26)-adamantyl-17-[20(22),23-diynyl]-21-norvitamin D Compounds

Journal of medicinal chemistry, 2015-12, Vol.58 (24), p.9510-9521

2015

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Combination of Triple Bond and Adamantane Ring on the Vitamin D Side Chain Produced Partial Agonists for Vitamin D Receptor

Journal of medicinal chemistry, 2014-05, Vol.57 (10), p.4073-4087

2014

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Identification of hepta-histidine as a candidate drug for Huntington's disease by in silico-in vitro- in vivo-integrated screens of chemical libraries

Scientific reports, 2016-09, Vol.6 (1), p.33861-33861, Article 33861

2016

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Crystal Structures of Rat Vitamin D Receptor Bound to Adamantyl Vitamin D Analogs: Structural Basis for Vitamin D Receptor Antagonism and Partial Agonism

Journal of medicinal chemistry, 2008-09, Vol.51 (17), p.5320-5329

2008

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Crystal structural analysis of protein–protein interactions drastically destabilized by a single mutation

Protein science, 2008-06, Vol.17 (6), p.1055-1065

2008

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Water-mediated interaction at a protein–protein interface

Chemical physics, 2004-12, Vol.307 (2), p.111-119

2004

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Crystal Structures of Hereditary Vitamin D‑Resistant Rickets-Associated Vitamin D Receptor Mutants R270L and W282R Bound to 1,25-Dihydroxyvitamin D3 and Synthetic Ligands

Journal of medicinal chemistry, 2013-09, Vol.56 (17), p.6745-6760

2013

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Crystal Structure of the Vitamin D Receptor Ligand-Binding Domain with Lithocholic Acids

Vitamins and hormones, 2016, Vol.100, p.117

2016

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Development of a novel selective inhibitor of the Down syndrome-related kinase Dyrk1A

Nature communications, 2010-10, Vol.1 (7), p.1-9, Article 86

2010

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Protein Globularization During Folding. A Study by Synchrotron Small-angle X-ray Scattering

Journal of molecular biology, 1996-10, Vol.262 (4), p.559-574

1996

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25 S-Adamantyl-23-yne-26,27-dinor-1α,25-dihydroxyvitamin D3: Synthesis, Tissue Selective Biological Activities, and X-ray Crystal Structural Analysis of Its Vitamin D Receptor Complex

Journal of medicinal chemistry, 2018-08, Vol.61 (15), p.6658-6673

2018

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Structural Analysis of Hen Egg Lysozyme Refolded after Denaturation at Acidic pH

Selective inhibition of the kinase DYRK1A by targeting its folding process

Energetics and kinetics of substrate analog-coupled staphylococcal nuclease folding revealed by a statistical mechanical approach

An Overlapping Region between the Two Terminal Folding Units of the Outer Surface Protein A (OspA) Controls Its Folding Behavior

Development of novel lithocholic acid derivatives as vitamin D receptor agonists

Crystal Structures and Thermodynamic Analysis Reveal Distinct Mechanisms of CD28 Phosphopeptide Binding to the Src Homology 2 (SH2) Domains of Three Adaptor Proteins

Crystal structures of complexes of vitamin D receptor ligand-binding domain with lithocholic acid derivatives

The trans isomer of Tau peptide is prone to aggregate, and the WW domain of Pin1 drastically decreases its aggregation

Mutational effects of Cys113 on structural dynamics of Pin1

HMGB1 signaling phosphorylates Ku70 and impairs DNA damage repair in Alzheimer's disease pathology

Requirements for peptidyl‐prolyl isomerization activity: A comprehensive mutational analysis of the substrate‐binding cavity of FK506‐binding protein 12

Creation of Cross-Linked Crystals With Intermolecular Disulfide Bonds Connecting Symmetry-Related Molecules Allows Retention of Tertiary Structure in Different Solvent Conditions

High resolution crystal structure of the Grb2 SH2 domain with a phosphopeptide derived from CD28

Fine tuning of agonistic/antagonistic activity for vitamin D receptor by 22-alkyl chain length of ligands: 22S-Hexyl compound unexpectedly restored agonistic activity

Synthesis, Biological Activities, and X‑ray Crystal Structural Analysis of 25-Hydroxy-25(or 26)-adamantyl-17-[20(22),23-diynyl]-21-norvitamin D Compounds

Combination of Triple Bond and Adamantane Ring on the Vitamin D Side Chain Produced Partial Agonists for Vitamin D Receptor

Identification of hepta-histidine as a candidate drug for Huntington's disease by in silico-in vitro- in vivo-integrated screens of chemical libraries

Crystal Structures of Rat Vitamin D Receptor Bound to Adamantyl Vitamin D Analogs: Structural Basis for Vitamin D Receptor Antagonism and Partial Agonism

Crystal structural analysis of protein–protein interactions drastically destabilized by a single mutation

Water-mediated interaction at a protein–protein interface

Crystal Structures of Hereditary Vitamin D‑Resistant Rickets-Associated Vitamin D Receptor Mutants R270L and W282R Bound to 1,25-Dihydroxyvitamin D3 and Synthetic Ligands

Crystal Structure of the Vitamin D Receptor Ligand-Binding Domain with Lithocholic Acids

Development of a novel selective inhibitor of the Down syndrome-related kinase Dyrk1A

Protein Globularization During Folding. A Study by Synchrotron Small-angle X-ray Scattering

25 S-Adamantyl-23-yne-26,27-dinor-1α,25-dihydroxyvitamin D3: Synthesis, Tissue Selective Biological Activities, and X-ray Crystal Structural Analysis of Its Vitamin D Receptor Complex

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