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Synthesis of (−)-Melodinine K: A Case Study of Efficiency in Natural Product Synthesis

Journal of natural products (Washington, D.C.), 2020-08, Vol.83 (8), p.2425-2433

2020

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Alternative approaches utilizing click chemistry to develop next-generation analogs of solithromycin

European journal of medicinal chemistry, 2022-04, Vol.233, p.114213-114213, Article 114213

2022

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Challenges and opportunities for natural product discovery, production, and engineering in native producers versus heterologous hosts

Journal of industrial microbiology & biotechnology, 2019-03, Vol.46 (3-4), p.433-444

2019

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Leveraging a large microbial strain collection for natural product discovery

The Journal of biological chemistry, 2019-11, Vol.294 (45), p.16567-16576

2019

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Intramolecular C–C Bond Formation Links Anthraquinone and Enediyne Scaffolds in Tiancimycin Biosynthesis

Journal of the American Chemical Society, 2022-11, Vol.144 (44), p.20452-20462

2022

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Application of a Biocatalytic Strategy for the Preparation of Tiancimycin-Based Antibody–Drug Conjugates Revealing Key Insights into Structure–Activity Relationships

Journal of medicinal chemistry, 2023-01, Vol.66 (2), p.1562-1573

2023

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Characterization of TnmH as an O‑Methyltransferase Revealing Insights into Tiancimycin Biosynthesis and Enabling a Biocatalytic Strategy To Prepare Antibody–Tiancimycin Conjugates

Journal of medicinal chemistry, 2020-08, Vol.63 (15), p.8432-8441

2020

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Functional Characterization of Cytochrome P450 Hydroxylase YpmL in Yangpumicin A Biosynthesis and Its Application for Anthraquinone-Fused Enediyne Structural Diversification

Organic letters, 2022-02, Vol.24 (5), p.1219-1223

2022

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Room‐Temperature Copper‐Catalyzed Etherification of Aryl Bromides

Angewandte Chemie International Edition, 2024-05, Vol.63 (19), p.e202400333-n/a

International ed. in English, 2024

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Comparative Studies of the Biosynthetic Gene Clusters for Anthraquinone-Fused Enediynes Shedding Light into the Tailoring Steps of Tiancimycin Biosynthesis

Organic letters, 2018-09, Vol.20 (18), p.5918-5921

2018

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Cytochrome P450 Hydroxylase TnmL Catalyzing Sequential Hydroxylation with an Additional Proofreading Activity in Tiancimycin Biosynthesis

ACS chemical biology, 2021-07, Vol.16 (7), p.1172-1178

2021

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A BAHD acyltransferase catalyzing 19‐O‐acetylation of tabersonine derivatives in roots of Catharanthus roseus enables combinatorial synthesis of monoterpene indole alkaloids

The Plant journal : for cell and molecular biology, 2018-05, Vol.94 (3), p.469-484

2018

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Submerged fermentation of Streptomyces uncialis providing a biotechnology platform for uncialamycin biosynthesis, engineering, and production

Journal of industrial microbiology & biotechnology, 2021-04, Vol.48 (3-4), p.1

2021

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Rational Approach to Identify RNA Targets of Natural Products Enables Identification of Nocathiacin as an Inhibitor of an Oncogenic RNA

ACS chemical biology, 2022-02, Vol.17 (2), p.474-482

2022

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Ribosome-Templated Azide–Alkyne Cycloadditions: Synthesis of Potent Macrolide Antibiotics by In Situ Click Chemistry

Journal of the American Chemical Society, 2016-03, Vol.138 (9), p.3136-3144

2016

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Biochemical and Structural Studies of the Carminomycin 4‑O‑Methyltransferase DnrK

Journal of natural products (Washington, D.C.), 2024-04, Vol.87 (4), p.798-809

2024

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In vivo Antimalarial and Antitrypanosomal Activity of Strychnogucine B, a Bisindole Alkaloid from Strychnos icaja

Planta medica, 2018-08, Vol.84 (12/13), p.881-885

2018

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Synthesis, Biological Evaluation, and Computational Analysis of Biaryl Side‐Chain Analogs of Solithromycin

ChemMedChem, 2021-11, Vol.16 (21), p.3368-3373

2021

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Synthesis and Biological Evaluation of Pentacyclic Strychnos Alkaloids as Selective Modulators of the ABCC10 (MRP7) Efflux Pump

Journal of medicinal chemistry, 2014-12, Vol.57 (24), p.10383-10390

2014

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Concise Syntheses of bis-Strychnos Alkaloids (−)-Sungucine, (−)-Isosungucine, and (−)-Strychnogucine B from (−)-Strychnine

Chemistry : a European journal, 2016-08, Vol.22 (33), p.11593-11596

2016

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Room‐Temperature Copper‐Catalyzed Etherification of Aryl Bromides

Angewandte Chemie, 2024-05, Vol.136 (19), p.n/a

2024

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Total Syntheses of (–)-Alstolucines A, B, and F, (–)-Echitamidine, and (–)-N-Demethylalstogucine

Synthesis (Stuttgart), 2015-06, Vol.47 (11), p.1547-1556

2015

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Cytochrome P450 Hydroxylase TnmL Catalyzing Sequential Hydroxylation with an Additional Proof-reading Activity in Tiancimycin Biosynthesis

ACS chemical biology, 2021-06, Vol.16 (7), p.1172-1178

2021

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Synthesis of Bis-Strychnos Alkaloids (–)-Sungucine, (–)-Isosungucine, and (–)-Strychnogucine B from (–)-Strychnine

Journal of the Brazilian Chemical Society, 2019-03, Vol.30 (3), p.436-453

2019

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Concise Syntheses of bis-Strychnos Alkaloids (-)-Sungucine, (-)-Isosungucine, and (-)-StrychnogucineB from (-)-Strychnine

Chemistry : a European journal, 2016-08, Vol.22 (33), p.11593-11596

2016

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Synthesis of (−)-Melodinine K: A Case Study of Efficiency in Natural Product Synthesis

Alternative approaches utilizing click chemistry to develop next-generation analogs of solithromycin

Challenges and opportunities for natural product discovery, production, and engineering in native producers versus heterologous hosts

Leveraging a large microbial strain collection for natural product discovery

Intramolecular C–C Bond Formation Links Anthraquinone and Enediyne Scaffolds in Tiancimycin Biosynthesis

Application of a Biocatalytic Strategy for the Preparation of Tiancimycin-Based Antibody–Drug Conjugates Revealing Key Insights into Structure–Activity Relationships

Characterization of TnmH as an O‑Methyltransferase Revealing Insights into Tiancimycin Biosynthesis and Enabling a Biocatalytic Strategy To Prepare Antibody–Tiancimycin Conjugates

Functional Characterization of Cytochrome P450 Hydroxylase YpmL in Yangpumicin A Biosynthesis and Its Application for Anthraquinone-Fused Enediyne Structural Diversification

Room‐Temperature Copper‐Catalyzed Etherification of Aryl Bromides

Comparative Studies of the Biosynthetic Gene Clusters for Anthraquinone-Fused Enediynes Shedding Light into the Tailoring Steps of Tiancimycin Biosynthesis

Cytochrome P450 Hydroxylase TnmL Catalyzing Sequential Hydroxylation with an Additional Proofreading Activity in Tiancimycin Biosynthesis

A BAHD acyltransferase catalyzing 19‐O‐acetylation of tabersonine derivatives in roots of Catharanthus roseus enables combinatorial synthesis of monoterpene indole alkaloids

Submerged fermentation of Streptomyces uncialis providing a biotechnology platform for uncialamycin biosynthesis, engineering, and production

Rational Approach to Identify RNA Targets of Natural Products Enables Identification of Nocathiacin as an Inhibitor of an Oncogenic RNA

Ribosome-Templated Azide–Alkyne Cycloadditions: Synthesis of Potent Macrolide Antibiotics by In Situ Click Chemistry

Biochemical and Structural Studies of the Carminomycin 4‑O‑Methyltransferase DnrK

In vivo Antimalarial and Antitrypanosomal Activity of Strychnogucine B, a Bisindole Alkaloid from Strychnos icaja

Synthesis, Biological Evaluation, and Computational Analysis of Biaryl Side‐Chain Analogs of Solithromycin

Synthesis and Biological Evaluation of Pentacyclic Strychnos Alkaloids as Selective Modulators of the ABCC10 (MRP7) Efflux Pump

Concise Syntheses of bis-Strychnos Alkaloids (−)-Sungucine, (−)-Isosungucine, and (−)-Strychnogucine B from (−)-Strychnine

Room‐Temperature Copper‐Catalyzed Etherification of Aryl Bromides

Total Syntheses of (–)-Alstolucines A, B, and F, (–)-Echitamidine, and (–)-N-Demethylalstogucine

Cytochrome P450 Hydroxylase TnmL Catalyzing Sequential Hydroxylation with an Additional Proof-reading Activity in Tiancimycin Biosynthesis

Synthesis of Bis-Strychnos Alkaloids (–)-Sungucine, (–)-Isosungucine, and (–)-Strychnogucine B from (–)-Strychnine

Concise Syntheses of bis-Strychnos Alkaloids (-)-Sungucine, (-)-Isosungucine, and (-)-StrychnogucineB from (-)-Strychnine

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