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Bioactivation of diclofenac via benzoquinone imine intermediates-identification of urinary mercapturic acid derivatives in rats and humans

Drug metabolism and disposition, 2001-12, Vol.29 (12), p.1608

2001

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Importance of mechanistic drug metabolism studies in support of drug discovery: A case study with an N -sulfonylated dipeptide VLA-4 antagonist in rats

Xenobiotica, 2008-02, Vol.38 (2), p.223-237

2008

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Metabolic activation of a pentafluorophenylethylamine derivative: Formation of glutathione conjugates in vitro in the rat

Xenobiotica, 2005-07, Vol.35 (7), p.697-713

2005

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Metabolic activation of fluoropyrrolidine dipeptidyl peptidase-IV inhibitors by rat liver microsomes

Drug metabolism and disposition, 2005-01, Vol.33 (1), p.121

2005

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Metabolic Activation of a 1,3-Disubstituted Piperazine Derivative: Evidence for a Novel Ring Contraction to an Imidazoline

Chemical research in toxicology, 2005-02, Vol.18 (2), p.271-276

2005

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Confirmation of the Binding Site of Cyclophilin-Cyclosporin Non-Covalent Complex Using Limited Proteolysis and Liquid Chromatography-Quadrupole-Time-of-Flight Mass Spectrometry

Journal of liquid chromatography & related technologies, 2005-06, Vol.28 (10), p.1497-1508

2005

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Replacing 14C with stable isotopes in drug metabolism studies

Drug metabolism and disposition, 1996-07, Vol.24 (7), p.697

1996

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Amidines as amide bond replacements in VLA-4 antagonists

Bioorganic & medicinal chemistry letters, 2004-05, Vol.14 (9), p.2323-2326

2004

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Continuous-Flow Isotope Ratio Mass Spectrometry Using the Chemical Reaction Interface with Either Gas or Liquid Chromatographic Introduction

Analytical chemistry (Washington), 1996-06, Vol.68 (11), p.1888-1894

1996

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Substituted 3-amino biaryl propionic acids as potent VLA-4 antagonists

Bioorganic & medicinal chemistry letters, 2002-09, Vol.12 (17), p.2415-2418

2002

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The Discovery of acylated β-Amino acids as potent and orally bioavailable VLA-4 antagonists

Bioorganic & medicinal chemistry letters, 2002-02, Vol.12 (4), p.611-614

2002

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Isotopic Differences in Human Growth Hormone Preparations

Analytical chemistry (Washington), 1996-06, Vol.68 (11), p.1971-1972

1996

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Element- and isotope-specific detection for high-performance liquid chromatography using chemical reaction interface mass spectrometry

Journal of Chromatography A, 1996-05, Vol.732 (2), p.189-199

1996

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Application of high-performance liquid chromatography/chemical reaction interface mass spectrometry for the analysis of conjugated metabolites: A demonstration using deuterated acetaminophen

Biological Mass Spectrometry, 1994-12, Vol.23 (12), p.776-783

1994

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Flow injection with chemical reaction interface–isotope ratio mass spectrometry: an alternative to off-line combustion for detecting low levels of enriched 13C in mass balance studies

Journal of the American Society for Mass Spectrometry, 1999-02, Vol.10 (2), p.153-158

1999

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Direct determination of human urinary cortisol metabolites by HPLC/CRIMS

Steroids, 1995-03, Vol.60 (3), p.295-298

1995

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Determination of benzo[a]pyrene sulfate conjugates from benzo[a]pyrene-treated cells by continuous-flow fast atom bombardment mass spectrometry

Analytical chemistry (Washington), 1991-03, Vol.63 (5), p.453-456

1991

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Studying the reaction between clozapine and glutathione with element-selective detection

Research communications in molecular pathology and pharmacology, 1998-02, Vol.99 (2), p.131

1998

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Development of an isotope-selective high-performance liquid chromatography detector using chemical-reaction-interface mass spectrometry: application to deuterated cortisol metabolites in urine

Journal of chromatography, 1993-10, Vol.620 (1), p.89-96

1993

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Development of an isotope-selective high-performance liquid chromatography detector using chemical-reaction-interface mass spectrometry : application to deuterated corticol metabolites in urine

Journal of chromatography. Biomedical applications, 1993, Vol.620 (1), p.89-96

1993

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Detection of benzo[ a]pyrene sulfate and glucuronide conjugates in cell culture medium by directly coupled microbore high-performance liquid chromatography—fast atom bombardment mass spectrometry

Journal of chromatography, 1992-05, Vol.577 (1), p.69-76

1992

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Prevalence of HIV and Its Co-Infection with Hepatitis B/C Virus Among Chronic Liver Disease Patients in Ethiopia

Hepatic medicine: evidence and research, 2022-05, Vol.14, p.67-77

2022

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Traverser ces années terribles » : l’activité scolaire des détenu·e·s politiques pendant la révolution éthiopienne (1979-1986): Entretien avec Hiwot Teffera. Propos recueillis par Pierre Guidi

Cahiers de la recherche sur l'éducation et les savoirs, 2019-07, Vol.18 (18), p.173-185

Guidi, Pierre

2019

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Discovery and optimization of potent and selective imidazopyridine and imidazopyridazine mTOR inhibitors

Bioorganic & medicinal chemistry letters, 2012-08, Vol.22 (15), p.4967-4974

2012

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Field trials on the repellent activity of four plant products against mainly Mansonia population in western Ethiopia

Phytotherapy research, 2003-03, Vol.17 (3), p.202-205

2003

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Bioactivation of diclofenac via benzoquinone imine intermediates-identification of urinary mercapturic acid derivatives in rats and humans

Importance of mechanistic drug metabolism studies in support of drug discovery: A case study with an N -sulfonylated dipeptide VLA-4 antagonist in rats

Metabolic activation of a pentafluorophenylethylamine derivative: Formation of glutathione conjugates in vitro in the rat

Metabolic activation of fluoropyrrolidine dipeptidyl peptidase-IV inhibitors by rat liver microsomes

Metabolic Activation of a 1,3-Disubstituted Piperazine Derivative: Evidence for a Novel Ring Contraction to an Imidazoline

Confirmation of the Binding Site of Cyclophilin-Cyclosporin Non-Covalent Complex Using Limited Proteolysis and Liquid Chromatography-Quadrupole-Time-of-Flight Mass Spectrometry

Replacing 14C with stable isotopes in drug metabolism studies

Amidines as amide bond replacements in VLA-4 antagonists

Continuous-Flow Isotope Ratio Mass Spectrometry Using the Chemical Reaction Interface with Either Gas or Liquid Chromatographic Introduction

Substituted 3-amino biaryl propionic acids as potent VLA-4 antagonists

The Discovery of acylated β-Amino acids as potent and orally bioavailable VLA-4 antagonists

Isotopic Differences in Human Growth Hormone Preparations

Element- and isotope-specific detection for high-performance liquid chromatography using chemical reaction interface mass spectrometry

Application of high-performance liquid chromatography/chemical reaction interface mass spectrometry for the analysis of conjugated metabolites: A demonstration using deuterated acetaminophen

Flow injection with chemical reaction interface–isotope ratio mass spectrometry: an alternative to off-line combustion for detecting low levels of enriched 13C in mass balance studies

Direct determination of human urinary cortisol metabolites by HPLC/CRIMS

Determination of benzo[a]pyrene sulfate conjugates from benzo[a]pyrene-treated cells by continuous-flow fast atom bombardment mass spectrometry

Studying the reaction between clozapine and glutathione with element-selective detection

Development of an isotope-selective high-performance liquid chromatography detector using chemical-reaction-interface mass spectrometry: application to deuterated cortisol metabolites in urine

Development of an isotope-selective high-performance liquid chromatography detector using chemical-reaction-interface mass spectrometry : application to deuterated corticol metabolites in urine

Detection of benzo[ a]pyrene sulfate and glucuronide conjugates in cell culture medium by directly coupled microbore high-performance liquid chromatography—fast atom bombardment mass spectrometry

Prevalence of HIV and Its Co-Infection with Hepatitis B/C Virus Among Chronic Liver Disease Patients in Ethiopia

Traverser ces années terribles » : l’activité scolaire des détenu·e·s politiques pendant la révolution éthiopienne (1979-1986): Entretien avec Hiwot Teffera. Propos recueillis par Pierre Guidi

Discovery and optimization of potent and selective imidazopyridine and imidazopyridazine mTOR inhibitors

Field trials on the repellent activity of four plant products against mainly Mansonia population in western Ethiopia

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