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Implications of protein flexibility for drug discovery

Nature reviews. Drug discovery, 2003-07, Vol.2 (7), p.527-541

Teague, Simon J

2003

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Synthesis of Heavily Substituted 2-Aminopyridines by Displacement of a 6-Methylsulfinyl Group

Journal of organic chemistry, 2008-12, Vol.73 (24), p.9765-9766

Teague, Simon J

2008

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Application and Limitations of X-ray Crystallographic Data in Structure-Based Ligand and Drug Design

Angewandte Chemie (International ed.), 2003-06, Vol.42 (24), p.2718-2736

2003

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Hydrogen Bonding, Hydrophobic Interactions, and Failure of the Rigid Receptor Hypothesis

Angewandte Chemie (International ed.), 1999-03, Vol.38 (6), p.736-749

1999

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The Design of Leadlike Combinatorial Libraries

Angewandte Chemie (International ed.), 1999-12, Vol.38 (24), p.3743-3748

1999

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Concrete evidence of confusion

Nature (London), 2010-10, Vol.467 (7318), p.920-920

Teague, Simon J

2010

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Euodenine A: A Small-Molecule Agonist of Human TLR4

Journal of medicinal chemistry, 2014-02, Vol.57 (4), p.1252-1275

2014

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Synthesis of melicodenines C, D and E

Tetrahedron letters, 2012-12, Vol.53 (52), p.7101-7103

2012

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Is There a Difference between Leads and Drugs? A Historical Perspective

Journal of Chemical Information and Computer Sciences, 2001-09, Vol.41 (5), p.1308-1315

2001

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Discovery of potent CRTh2 (DP 2) receptor antagonists

Bioorganic & medicinal chemistry letters, 2006-08, Vol.16 (16), p.4287-4290

2006

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Synthesis of 6-substituted 5-cyano-7-hydroxy-2-carboxybenzofurans

Tetrahedron letters, 2010-09, Vol.51 (36), p.4720-4722

2010

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Facile synthesis of a o-nitrobenzyl photolabile linker for combinatorial chemistry

Tetrahedron letters, 1996-08, Vol.37 (32), p.5751-5754

Teague, Simon J

1996

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Solid-Phase Total Synthesis of Oscillamide Y and Analogues

Journal of organic chemistry, 1997-09, Vol.62 (18), p.6199-6203

1997

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Library synthesis using solution phase capping of solid phase derived intermediates

Tetrahedron letters, 2000-03, Vol.41 (12), p.2023-2026

2000

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Hydrogen Bonding, Hydrophobic Interactions, and Failure of the Rigid Receptor Hypothesis

Angewandte Chemie International Edition, 1999-03, Vol.38 (6), p.736-749

1999

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Asymmetric total synthesis of (-)-podophyllotoxin

Journal of the American Chemical Society, 1988-11, Vol.110 (23), p.7854-7858

1988

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Macrocyclic ring closures employing the Intramolecular Heck reaction

Tetrahedron letters, 1995-09, Vol.36 (36), p.6555-6558

1995

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Discovery and synthesis of methyl 2,5-dimethyl-4-[2-(phenylmethyl)benzoyl]-1H-pyrrole-3-carboxylate (FPL 64176) and analogs: the first examples of a new class of calcium channel activator

Journal of medicinal chemistry, 1993-09, Vol.36 (19), p.2739-2744

1993

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Synthesis of benzimidazole based JNK inhibitors

Tetrahedron letters, 2005-07, Vol.46 (27), p.4613-4616

2005

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CHAPTER 3 - Phenotypic Screening to Discover Inhibitors of Dengue Virus

Successful Strategies for the Discovery of Antiviral Drugs, 2013, p.63-80

2013

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Anwendung und Grenzen kristallographischer Daten im strukturbezogenen Liganden- und Wirkstoff-Design

Angewandte Chemie, 2003-06, Vol.115 (24), p.2822-2841

2003

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The Synthesis of Highly Functionalized Naphthalene Derivatives

Synthesis (Stuttgart), 1986, Vol.1986 (5), p.427-429

1986

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Die Bedeutung der Balance von Wasserstoffbrückenbindungen und hydrophoben Wechselwirkungen im Wirkstoff-Rezeptor-Komplex

Angewandte Chemie, 1999-03, Vol.111 (6), p.778-792

1999

Volltextzugriff (PDF)

ChemInform Abstract: Synthesis of Heavily Substituted 2-Aminopyridines by Displacement of a 6-Methylsulfinyl Group

ChemInform, 2009-04, Vol.40 (16), p.no-no

Teague, Simon J.

2009

Volltextzugriff (PDF)

Transannular cyclisation as a stratagem in synthesis. A total synthesis of (±)-pentalenene

Tetrahedron, 1987, Vol.43 (23), p.5637-5652

1987

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Implications of protein flexibility for drug discovery

Synthesis of Heavily Substituted 2-Aminopyridines by Displacement of a 6-Methylsulfinyl Group

Application and Limitations of X-ray Crystallographic Data in Structure-Based Ligand and Drug Design

Hydrogen Bonding, Hydrophobic Interactions, and Failure of the Rigid Receptor Hypothesis

The Design of Leadlike Combinatorial Libraries

Concrete evidence of confusion

Euodenine A: A Small-Molecule Agonist of Human TLR4

Synthesis of melicodenines C, D and E

Is There a Difference between Leads and Drugs? A Historical Perspective

Discovery of potent CRTh2 (DP 2) receptor antagonists

Synthesis of 6-substituted 5-cyano-7-hydroxy-2-carboxybenzofurans

Facile synthesis of a o-nitrobenzyl photolabile linker for combinatorial chemistry

Solid-Phase Total Synthesis of Oscillamide Y and Analogues

Library synthesis using solution phase capping of solid phase derived intermediates

Hydrogen Bonding, Hydrophobic Interactions, and Failure of the Rigid Receptor Hypothesis

Asymmetric total synthesis of (-)-podophyllotoxin

Macrocyclic ring closures employing the Intramolecular Heck reaction

Discovery and synthesis of methyl 2,5-dimethyl-4-[2-(phenylmethyl)benzoyl]-1H-pyrrole-3-carboxylate (FPL 64176) and analogs: the first examples of a new class of calcium channel activator

Synthesis of benzimidazole based JNK inhibitors

CHAPTER 3 - Phenotypic Screening to Discover Inhibitors of Dengue Virus

Anwendung und Grenzen kristallographischer Daten im strukturbezogenen Liganden- und Wirkstoff-Design

The Synthesis of Highly Functionalized Naphthalene Derivatives

Die Bedeutung der Balance von Wasserstoffbrückenbindungen und hydrophoben Wechselwirkungen im Wirkstoff-Rezeptor-Komplex

ChemInform Abstract: Synthesis of Heavily Substituted 2-Aminopyridines by Displacement of a 6-Methylsulfinyl Group

Transannular cyclisation as a stratagem in synthesis. A total synthesis of (±)-pentalenene

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