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Mechanism-based screen for G1/S checkpoint activators identifies a selective activator of EIF2AK3/PERK signalling

PloS one, 2012-01, Vol.7 (1), p.e28568

2012

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The Cyclin-Dependent Kinase Inhibitor Seliciclib (R-roscovitine; CYC202) Decreases the Expression of Mitotic Control Genes and Prevents Entry into Mitosis

Cell cycle (Georgetown, Tex.), 2007-12, Vol.6 (24), p.3114-3131

2007

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DNA damage is able to induce senescence in tumor cells in vitro and in vivo

Cancer research (Chicago, Ill.), 2002-03, Vol.62 (6), p.1876-1883

2002

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AT13148 Is a Novel, Oral Multi-AGC Kinase Inhibitor with Potent Pharmacodynamic and Antitumor Activity

Clinical cancer research, 2012-07, Vol.18 (14), p.3912-3923

2012

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RNA synthesis block by 5, 6-dichloro-1-beta-D-ribofuranosylbenzimidazole (DRB) triggers p53-dependent apoptosis in human colon carcinoma cells

Oncogene, 1999-10, Vol.18 (42), p.5765-5772

1999

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Histone Deacetylase Inhibition Increases Levels of Choline Kinase α and Phosphocholine Facilitating Noninvasive Imaging in Human Cancers

Cancer research (Chicago, Ill.), 2012-02, Vol.72 (4), p.990-1000

2012

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Correlation of Overall Survival With Gene Expression Profiles in a Prospective Study of Resectable Esophageal Cancer

Clinical colorectal cancer, 2011-03, Vol.10 (1), p.48-56

2011

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Abstract 2998: Molecular and cellular effects of individual and combinatorial silencing of HSP90 paralogs

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.2998-2998

2016

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Abstract 6441: Discovery of ARID1A loss as a patient biomarker for NXP800 - A developmental activator of the integrated stress response (ISR) and inhibitor of the HSF1 pathway in ovarian cancer

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.6441-6441

2024

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Recent Advances and Developments in the Inhibitors of DNA Topoisomerases

Current enzyme inhibition, 2007-05, Vol.3 (2), p.161-174

2007

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Histone deacetylase inhibition increases levels of choline kinase alpha and phosphocholine facilitating non-invasive imaging in human cancers

Cancer research (Chicago, Ill.), 2011-12, Vol.72 (4), p.990-1000

2011

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Abstract 928: The novel clinical candidate AT13148 is an oral multi-AGC kinase inhibitor with potent pharmacodynamic and antitumor activity and demonstrates a mechanism of action distinct from AKT inhibitors

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8_Supplement), p.928-928

2012

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Niacin induces PPARgamma expression and transcriptional activation in macrophages via HM74 and HM74a-mediated induction of prostaglandin synthesis pathways

Biochemical pharmacology, 2006-02, Vol.71 (5), p.646

2006

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Re: Loss of DNA Mismatch Repair: Effects on the Rate of Mutation to Drug Resistance

JNCI : Journal of the National Cancer Institute, 1998-02, Vol.90 (3), p.246-246

1998

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Re: Loss of DNA mismatch repair: Effects on the rate of mutation to drug resistance / Response

JNCI : Journal of the National Cancer Institute, 1998-02, Vol.90 (3), p.246

1998

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Gene Microarray Technologies for Cancer Drug Discovery and Development

Molecular Cancer Therapeutics, 2004, p.141-186

2004

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3-Hydroxybenzoate 6-Hydroxylase from Rhodococcus jostii RHA1 Contains a Phosphatidylinositol Cofactor

Frontiers in microbiology, 2017-06, Vol.8, p.1110-1110

2017

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AHR- and DNA-Damage-Mediated Gene Expression Responses Induced by Benzo(a)pyrene in Human Cell Lines

Chemical research in toxicology, 2007-12, Vol.20 (12), p.1797-1810

2007

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An Efficient System for Active Bovine Pancreatic Ribonuclease Expression in Escherichia coli

Protein expression and purification, 1995-08, Vol.6 (4), p.472-480

1995

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Mechanism-based screen for G1/S checkpoint activators identifies a selective activator of EIF2AK3/PERK signalling

The Cyclin-Dependent Kinase Inhibitor Seliciclib (R-roscovitine; CYC202) Decreases the Expression of Mitotic Control Genes and Prevents Entry into Mitosis

DNA damage is able to induce senescence in tumor cells in vitro and in vivo

AT13148 Is a Novel, Oral Multi-AGC Kinase Inhibitor with Potent Pharmacodynamic and Antitumor Activity

RNA synthesis block by 5, 6-dichloro-1-beta-D-ribofuranosylbenzimidazole (DRB) triggers p53-dependent apoptosis in human colon carcinoma cells

Histone Deacetylase Inhibition Increases Levels of Choline Kinase α and Phosphocholine Facilitating Noninvasive Imaging in Human Cancers

Correlation of Overall Survival With Gene Expression Profiles in a Prospective Study of Resectable Esophageal Cancer

Abstract 2998: Molecular and cellular effects of individual and combinatorial silencing of HSP90 paralogs

Abstract 6441: Discovery of ARID1A loss as a patient biomarker for NXP800 - A developmental activator of the integrated stress response (ISR) and inhibitor of the HSF1 pathway in ovarian cancer

Recent Advances and Developments in the Inhibitors of DNA Topoisomerases

Histone deacetylase inhibition increases levels of choline kinase alpha and phosphocholine facilitating non-invasive imaging in human cancers

Abstract 928: The novel clinical candidate AT13148 is an oral multi-AGC kinase inhibitor with potent pharmacodynamic and antitumor activity and demonstrates a mechanism of action distinct from AKT inhibitors

Niacin induces PPARgamma expression and transcriptional activation in macrophages via HM74 and HM74a-mediated induction of prostaglandin synthesis pathways

Re: Loss of DNA Mismatch Repair: Effects on the Rate of Mutation to Drug Resistance

Re: Loss of DNA mismatch repair: Effects on the rate of mutation to drug resistance / Response

Gene Microarray Technologies for Cancer Drug Discovery and Development

3-Hydroxybenzoate 6-Hydroxylase from Rhodococcus jostii RHA1 Contains a Phosphatidylinositol Cofactor

AHR- and DNA-Damage-Mediated Gene Expression Responses Induced by Benzo(a)pyrene in Human Cell Lines

An Efficient System for Active Bovine Pancreatic Ribonuclease Expression in Escherichia coli

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