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Splicing-directed therapy in a new mouse model of human accelerated aging

Science translational medicine, 2011-10, Vol.3 (106), p.106ra107

2011

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The RasGAP-Associated Endoribonuclease G3BP Assembles Stress Granules

The Journal of cell biology, 2003-03, Vol.160 (6), p.823-831

2003

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Hypermethylation of the Cap Structure of Both Yeast snRNAs and snoRNAs Requires a Conserved Methyltransferase that Is Localized to the Nucleolus

Molecular cell, 2002-04, Vol.9 (4), p.891-901

2002

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Pharmacological modulation of LMNA SRSF1-dependent splicing abrogates diet-induced obesity in mice

International Journal of Obesity, 2017-03, Vol.41 (3), p.390-401

2017

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mRNA degradation machines in eukaryotic cells

Biochimie, 2002-08, Vol.84 (8), p.821-837

2002

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The spliceosome: a novel multi-faceted target for therapy

Trends in biochemical sciences (Amsterdam. Regular ed.), 2005-08, Vol.30 (8), p.469-478

2005

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Control of Fetal Growth and Neonatal Survival by the RasGAP-Associated Endoribonuclease G3BP

Molecular and Cellular Biology, 2005-10, Vol.25 (19), p.8703-8716

2005

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RasGAP-Associated Endoribonuclease G3BP: Selective RNA Degradation and Phosphorylation-Dependent Localization

Molecular and Cellular Biology, 2001-11, Vol.21 (22), p.7747-7760

2001

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Regulation of cytoplasmic stress granules by apoptosis-inducing factor

Journal of cell science, 2004-09, Vol.117 (Pt 19), p.4461-4468

2004

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Specific inhibition of serine- and arginine-rich splicing factors phosphorylation, spliceosome assembly, and splicing by the antitumor drug NB-506

Cancer research (Chicago, Ill.), 2001-09, Vol.61 (18), p.6876-6884

2001

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Interaction between the small-nuclear-RNA cap hypermethylase and the spinal muscular atrophy protein, survival of motor neuron

EMBO reports, 2003-06, Vol.4 (6), p.616-622

2003

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Alternative chromatin structure at CpG islands

Cell, 1990-03, Vol.60 (6), p.909-920

1990

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Altered serine/arginine-rich protein phosphorylation and exonic enhancer-dependent splicing in mammalian cells lacking topoisomerase I

Cancer research (Chicago, Ill.), 2003-12, Vol.63 (23), p.8203-8211

2003

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P025 Obefazimod and its active metabolites ABX-464-N-Glu act by stabilizing protein-protein interaction among key RNA biogenesis partners, CBC and ARS2

Journal of Crohn's and colitis, 2024-01, Vol.18 (Supplement_1), p.i279-i279

2024

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Selective Inhibition of Topoisomerase I and Various Steps of Spliceosome Assembly by Diospyrin Derivatives

Molecular pharmacology, 2005-04, Vol.67 (4), p.1186-1194

2005

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A Novel Phosphorylation-Dependent RNase Activity of GAP-SH3 Binding Protein: a Potential Link between Signal Transduction and RNA Stability

Molecular and Cellular Biology, 1998-07, Vol.18 (7), p.3956-3965

1998

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Sequence-structure-function relationships of Tgs1, the yeast snRNA/snoRNA cap hypermethylase

Nucleic acids research, 2003-08, Vol.31 (16), p.4899

2003

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Interaction of human DNA topoisomerase I with G-quartet structures

Nucleic acids research, 2000-12, Vol.28 (24), p.4832

2000

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RBFOX2 Is an Important Regulator of Mesenchymal Tissue-Specific Splicing in both Normal and Cancer Tissues

Molecular and Cellular Biology, 2013-01, Vol.33 (2), p.396-405

2013

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Topoisomerase I and II inhibitors control caspase-2 pre-messenger RNA splicing in human cells

Molecular cancer research, 2004-01, Vol.2 (1), p.53-61

2004

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Resistance to senescence induction and telomere shortening by a G-quadruplex ligand inhibitor of telomerase

Cancer research (Chicago, Ill.), 2003-10, Vol.63 (19), p.6149-6153

2003

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Identification of two human nuclear proteins that recognise the cytosine-rich strand of human telomeres in vitro

Nucleic acids research, 2000-04, Vol.28 (7), p.1564

2000

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Regulated functional alternative splicing in Drosophila

Nucleic acids research, 2012-01, Vol.40 (1), p.1

2012

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Revisiting G3BP1 as a RasGAP binding protein: sensitization of tumor cells to chemotherapy by the RasGAP 317-326 sequence does not involve G3BP1

PloS one, 2011-12, Vol.6 (12), p.e29024

2011

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The sirtuin SIRT6 regulates stress granule formation in C. elegans and mammals

Journal of cell science, 2013-11, Vol.126 (Pt 22), p.5166-5177

2013

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Splicing-directed therapy in a new mouse model of human accelerated aging

The RasGAP-Associated Endoribonuclease G3BP Assembles Stress Granules

Hypermethylation of the Cap Structure of Both Yeast snRNAs and snoRNAs Requires a Conserved Methyltransferase that Is Localized to the Nucleolus

Pharmacological modulation of LMNA SRSF1-dependent splicing abrogates diet-induced obesity in mice

mRNA degradation machines in eukaryotic cells

The spliceosome: a novel multi-faceted target for therapy

Control of Fetal Growth and Neonatal Survival by the RasGAP-Associated Endoribonuclease G3BP

RasGAP-Associated Endoribonuclease G3BP: Selective RNA Degradation and Phosphorylation-Dependent Localization

Regulation of cytoplasmic stress granules by apoptosis-inducing factor

Specific inhibition of serine- and arginine-rich splicing factors phosphorylation, spliceosome assembly, and splicing by the antitumor drug NB-506

Interaction between the small-nuclear-RNA cap hypermethylase and the spinal muscular atrophy protein, survival of motor neuron

Alternative chromatin structure at CpG islands

Altered serine/arginine-rich protein phosphorylation and exonic enhancer-dependent splicing in mammalian cells lacking topoisomerase I

P025 Obefazimod and its active metabolites ABX-464-N-Glu act by stabilizing protein-protein interaction among key RNA biogenesis partners, CBC and ARS2

Selective Inhibition of Topoisomerase I and Various Steps of Spliceosome Assembly by Diospyrin Derivatives

A Novel Phosphorylation-Dependent RNase Activity of GAP-SH3 Binding Protein: a Potential Link between Signal Transduction and RNA Stability

Sequence-structure-function relationships of Tgs1, the yeast snRNA/snoRNA cap hypermethylase

Interaction of human DNA topoisomerase I with G-quartet structures

RBFOX2 Is an Important Regulator of Mesenchymal Tissue-Specific Splicing in both Normal and Cancer Tissues

Topoisomerase I and II inhibitors control caspase-2 pre-messenger RNA splicing in human cells

Resistance to senescence induction and telomere shortening by a G-quadruplex ligand inhibitor of telomerase

Identification of two human nuclear proteins that recognise the cytosine-rich strand of human telomeres in vitro

Regulated functional alternative splicing in Drosophila

Revisiting G3BP1 as a RasGAP binding protein: sensitization of tumor cells to chemotherapy by the RasGAP 317-326 sequence does not involve G3BP1

The sirtuin SIRT6 regulates stress granule formation in C. elegans and mammals

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