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Synthetic Genetic Polymers Capable of Heredity and Evolution

Science (American Association for the Advancement of Science), 2012-04, Vol.336 (6079), p.341-344

2012

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XNAzymes targeting the SARS-CoV-2 genome inhibit viral infection

Nature communications, 2022-11, Vol.13 (1), p.6716-12, Article 6716

2022

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Towards applications of synthetic genetic polymers in diagnosis and therapy

Current opinion in chemical biology, 2014-10, Vol.22, p.79-84

2014

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General Principles Underpinning Amyloid Structure

Frontiers in neuroscience, 2022-06, Vol.16, p.878869-878869

2022

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A two-step biopolymer nucleation model shows a nonequilibrium critical point

The Journal of chemical physics, 2020-07, Vol.153 (2), p.025102-025102

2020

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Random-sequence genetic oligomer pools display an innate potential for ligation and recombination

eLife, 2018-11, Vol.7

2018

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Targeting non-coding RNA family members with artificial endonuclease XNAzymes

Communications biology, 2022-09, Vol.5 (1), p.1010-1010, Article 1010

2022

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Beyond DNA and RNA: The Expanding Toolbox of Synthetic Genetics

Cold Spring Harbor perspectives in biology, 2019-06, Vol.11 (6), p.a032490

2019

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Directed evolution of artificial enzymes (XNAzymes) from diverse repertoires of synthetic genetic polymers

Nature protocols, 2015-10, Vol.10 (10), p.1625-1642

2015

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A modular XNAzyme cleaves long, structured RNAs under physiological conditions and enables allele-specific gene silencing

Nature chemistry, 2022-11, Vol.14 (11), p.1295

2022

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Discovery and evolution of RNA and XNA reverse transcriptase function and fidelity

Nature chemistry, 2020-08, Vol.12 (8), p.683

2020

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A two-residue nascent-strand steric gate controls synthesis of 2'-O-methyl- and 2'-O-(2-methoxyethyl)-RNA

Nature chemistry, 2023-01, Vol.15 (1), p.91

2023

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A synthetic genetic polymer with an uncharged backbone chemistry based on alkyl phosphonate nucleic acids

Nature chemistry, 2019-06, Vol.11 (6), p.533

2019

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Catalysts from synthetic genetic polymers

Nature (London), 2015-02, Vol.518 (7539), p.427-430

2015

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Structural evolution of fibril polymorphs during amyloid assembly

Cell, 2023-12, Vol.186 (26), p.5798-5811.e26

2023

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Avian IgY Binds to a Monocyte Receptor with IgG-like Kinetics Despite an IgE-like Structure

The Journal of biological chemistry, 2008-06, Vol.283 (24), p.16384-16390

2008

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Mutations in an avian IgY-Fc fragment reveal the locations of monocyte Fc receptor binding sites

Developmental and comparative immunology, 2010-02, Vol.34 (2), p.97-101

2010

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A Monomeric Chicken IgY Receptor Binds IgY with 2:1 Stoichiometry

The Journal of biological chemistry, 2009-09, Vol.284 (36), p.24168-24175

2009

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Characterization of an HNA aptamer suggests a non-canonical G-quadruplex motif

Nucleic acids research, 2023-08, Vol.51 (15), p.7736

2023

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Enzymatic Synthesis of Nucleic Acids with Defined Regioisomeric 2′-5′ Linkages

Angewandte Chemie (International ed.), 2015-12, Vol.54 (51), p.15570-15573

International ed. in English, 2015

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Nanostructures from Synthetic Genetic Polymers

Chembiochem : a European journal of chemical biology, 2016-06, Vol.17 (12), p.1107-1110

2016

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Efficient synthesis and replication of diverse sequence libraries composed of biostable nucleic acid analogues

RSC chemical biology, 2022-10, Vol.3 (1), p.129-1215

2022

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Simple, Reliable Protocol for High-Yield Solubilization of Seedless Amyloid‑β Monomer

ACS chemical neuroscience, 2023-01, Vol.14 (1), p.53-71

2023

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The Crystal Structure of an Avian IgY-Fc Fragment Reveals Conservation with both Mammalian IgG and IgE

Biochemistry (Easton), 2009-01, Vol.48 (3), p.558-562

2009

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Selecting Fully‐Modified XNA Aptamers Using Synthetic Genetics

Current protocols in chemical biology, 2018-06, Vol.10 (2), p.e44-n/a

2018

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Synthetic Genetic Polymers Capable of Heredity and Evolution

XNAzymes targeting the SARS-CoV-2 genome inhibit viral infection

Towards applications of synthetic genetic polymers in diagnosis and therapy

General Principles Underpinning Amyloid Structure

A two-step biopolymer nucleation model shows a nonequilibrium critical point

Random-sequence genetic oligomer pools display an innate potential for ligation and recombination

Targeting non-coding RNA family members with artificial endonuclease XNAzymes

Beyond DNA and RNA: The Expanding Toolbox of Synthetic Genetics

Directed evolution of artificial enzymes (XNAzymes) from diverse repertoires of synthetic genetic polymers

A modular XNAzyme cleaves long, structured RNAs under physiological conditions and enables allele-specific gene silencing

Discovery and evolution of RNA and XNA reverse transcriptase function and fidelity

A two-residue nascent-strand steric gate controls synthesis of 2'-O-methyl- and 2'-O-(2-methoxyethyl)-RNA

A synthetic genetic polymer with an uncharged backbone chemistry based on alkyl phosphonate nucleic acids

Catalysts from synthetic genetic polymers

Structural evolution of fibril polymorphs during amyloid assembly

Avian IgY Binds to a Monocyte Receptor with IgG-like Kinetics Despite an IgE-like Structure

Mutations in an avian IgY-Fc fragment reveal the locations of monocyte Fc receptor binding sites

A Monomeric Chicken IgY Receptor Binds IgY with 2:1 Stoichiometry

Characterization of an HNA aptamer suggests a non-canonical G-quadruplex motif

Enzymatic Synthesis of Nucleic Acids with Defined Regioisomeric 2′-5′ Linkages

Nanostructures from Synthetic Genetic Polymers

Efficient synthesis and replication of diverse sequence libraries composed of biostable nucleic acid analogues

Simple, Reliable Protocol for High-Yield Solubilization of Seedless Amyloid‑β Monomer

The Crystal Structure of an Avian IgY-Fc Fragment Reveals Conservation with both Mammalian IgG and IgE

Selecting Fully‐Modified XNA Aptamers Using Synthetic Genetics

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