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Pathogenic variants of the mitochondrial aspartate/glutamate carrier causing citrin deficiency

Trends in endocrinology and metabolism, 2022-08, Vol.33 (8), p.539-553

2022

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Substrate binding in the mitochondrial ADP/ATP carrier is a step-wise process guiding the structural changes in the transport cycle

Nature communications, 2022-06, Vol.13 (1), p.3585-3585, Article 3585

2022

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The transport mechanism of the mitochondrial ADP/ATP carrier

Biochimica et biophysica acta, 2016-10, Vol.1863 (10), p.2379-2393

2016

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Fluoxetine (Prozac) Binding to Serotonin Transporter Is Modulated by Chloride and Conformational Changes

The Journal of neuroscience, 2009-07, Vol.29 (30), p.9635-9643

2009

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Identification of a chloride ion binding site in Na⁺/Cl⁻-dependent transporters

Proceedings of the National Academy of Sciences - PNAS, 2007-07, Vol.104 (31), p.12761-12766

2007

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Key features of inhibitor binding to the human mitochondrial pyruvate carrier hetero-dimer

Molecular metabolism (Germany), 2022-06, Vol.60, p.101469-101469, Article 101469

2022

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A Single Cysteine Residue in the Translocation Pathway of the Mitosomal ADP/ATP Carrier from Cryptosporidium parvum Confers a Broad Nucleotide Specificity

International journal of molecular sciences, 2020-11, Vol.21 (23), p.8971

2020

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Distinct roles for the domains of the mitochondrial aspartate/glutamate carrier citrin in organellar localization and substrate transport

Molecular metabolism (Germany), 2024-12, Vol.90, p.102047, Article 102047

2024

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Bioenergetic deficits in cellular models of Citrin Deficiency

Biochimica et biophysica acta. Bioenergetics, 2024-09, Vol.1865, p.149412, Article 149412

2024

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Fifty years of the mitochondrial pyruvate carrier: New insights into its structure, function, and inhibition

Acta Physiologica, 2023-08, Vol.238 (4), p.e14016-n/a

2023

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To be, or not to be two sites: that is the question about LeuT substrate binding

The Journal of general physiology, 2011-10, Vol.138 (4), p.467-471

2011

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Identification of the Inhibitor Binding Site of the Human Mitochondrial Pyruvate Carrier

Biochimica et biophysica acta. Bioenergetics, 2024-09, Vol.1865, p.149343, Article 149343

2024

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The yeast mitochondrial pyruvate carrier is a hetero‐dimer in its functional state

The EMBO journal, 2019-05, Vol.38 (10), p.n/a

2019

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The Concise Guide to PHARMACOLOGY 2023/24: Transporters

British journal of pharmacology, 2023-10, Vol.180 (S2), p.S374-S469

2023

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Structural elements required for coupling ion and substrate transport in the neurotransmitter transporter homolog LeuT

Proceedings of the National Academy of Sciences - PNAS, 2018-09, Vol.115 (38), p.E8854-E8862

2018

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Pathogenic mechanisms by the mitochondrial aspartate/glutamate carrier mutations in citrin deficiency

Biochimica et biophysica acta. Bioenergetics, 2024-09, Vol.1865, p.149187, Article 149187

2024

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Two Na+ Sites Control Conformational Change in a Neurotransmitter Transporter Homolog

The Journal of biological chemistry, 2016-01, Vol.291 (3), p.1456-1471

2016

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The model of citrin deficiency: Adopting a new approach to rare diseases

Molecular genetics and metabolism, 2024-04, Vol.141 (4), p.108274, Article 108274

2024

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To be, or not to be two sites: that is the question about LeuT substrate binding

The Journal of general physiology, 2011-09, Vol.138 (4), p.467-471

2011

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Structure and Regulatory Interactions of the Cytoplasmic Terminal Domains of Serotonin Transporter

Biochemistry (Easton), 2014-08, Vol.53 (33), p.5444-5460

2014

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Reconstructing a Chloride-binding Site in a Bacterial Neurotransmitter Transporter Homologue

The Journal of biological chemistry, 2011-01, Vol.286 (4), p.2834-2842

2011

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Effective Navigation of Query Results Based on Concept Hierarchies

IEEE transactions on knowledge and data engineering, 2011-04, Vol.23 (4), p.540-553

2011

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SLC54 Mitochondrial pyruvate carriers in GtoPdb v.2023.1

IUPHAR/BPS Guide to Pharmacology CITE, 2023-04, Vol.2023 (1)

2023

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Substrate Selectivity of the Melibiose Permease (MelY) from Enterobacter cloacae

Journal of molecular biology, 2008-02, Vol.376 (3), p.681-693

2008

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Corrigendum to “The transport mechanism of the mitochondrial ADP/ATP carrier” [Biochim. Biophys. Acta 1863/10 (2016) 2379–2393]

Biochimica et biophysica acta. Molecular cell research, 2016-12, Vol.1863 (12), p.3169-3169

2016

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Pathogenic variants of the mitochondrial aspartate/glutamate carrier causing citrin deficiency

Substrate binding in the mitochondrial ADP/ATP carrier is a step-wise process guiding the structural changes in the transport cycle

The transport mechanism of the mitochondrial ADP/ATP carrier

Fluoxetine (Prozac) Binding to Serotonin Transporter Is Modulated by Chloride and Conformational Changes

Identification of a chloride ion binding site in Na⁺/Cl⁻-dependent transporters

Key features of inhibitor binding to the human mitochondrial pyruvate carrier hetero-dimer

A Single Cysteine Residue in the Translocation Pathway of the Mitosomal ADP/ATP Carrier from Cryptosporidium parvum Confers a Broad Nucleotide Specificity

Distinct roles for the domains of the mitochondrial aspartate/glutamate carrier citrin in organellar localization and substrate transport

Bioenergetic deficits in cellular models of Citrin Deficiency

Fifty years of the mitochondrial pyruvate carrier: New insights into its structure, function, and inhibition

To be, or not to be two sites: that is the question about LeuT substrate binding

Identification of the Inhibitor Binding Site of the Human Mitochondrial Pyruvate Carrier

The yeast mitochondrial pyruvate carrier is a hetero‐dimer in its functional state

The Concise Guide to PHARMACOLOGY 2023/24: Transporters

Structural elements required for coupling ion and substrate transport in the neurotransmitter transporter homolog LeuT

Pathogenic mechanisms by the mitochondrial aspartate/glutamate carrier mutations in citrin deficiency

Two Na+ Sites Control Conformational Change in a Neurotransmitter Transporter Homolog

The model of citrin deficiency: Adopting a new approach to rare diseases

To be, or not to be two sites: that is the question about LeuT substrate binding

Structure and Regulatory Interactions of the Cytoplasmic Terminal Domains of Serotonin Transporter

Reconstructing a Chloride-binding Site in a Bacterial Neurotransmitter Transporter Homologue

Effective Navigation of Query Results Based on Concept Hierarchies

SLC54 Mitochondrial pyruvate carriers in GtoPdb v.2023.1

Substrate Selectivity of the Melibiose Permease (MelY) from Enterobacter cloacae

Corrigendum to “The transport mechanism of the mitochondrial ADP/ATP carrier” [Biochim. Biophys. Acta 1863/10 (2016) 2379–2393]

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