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ITC Recommendations for Transporter Kinetic Parameter Estimation and Translational Modeling of Transport-Mediated PK and DDIs in Humans

Clinical pharmacology and therapeutics, 2013-07, Vol.94 (1), p.64-79

2013

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Pharmacokinetic Evaluation of a Drug Transporter Cocktail Consisting of Digoxin, Furosemide, Metformin, and Rosuvastatin

Clinical pharmacology and therapeutics, 2016-09, Vol.100 (3), p.259-267

2016

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Effect of its deaminated metabolite, 2′,2′-difluorodeoxyuridine, on the transport and toxicity of gemcitabine in HeLa cells

Biochemical pharmacology, 2011-04, Vol.81 (7), p.950-956

2011

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Brefeldin A enhances receptor-mediated transcytosis of transferrin in filter-grown Madin-Darby canine kidney cells

The Journal of biological chemistry, 1992-07, Vol.267 (19), p.13446-13450

1992

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Dipeptide model prodrugs for the intestinal oligopeptide transporter. Affinity for and transport via hPepT1 in the human intestinal Caco-2 cell line

Journal of controlled release, 2001-09, Vol.76 (1), p.129-138

2001

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Stability and in vitro metabolism of dipeptide model prodrugs with affinity for the oligopeptide transporter

European journal of pharmaceutical sciences, 2000-07, Vol.11 (1), p.43-50

2000

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Stability, metabolism and transport of d-Asp(OBzl)–Ala — a model prodrug with affinity for the oligopeptide transporter

European journal of pharmaceutical sciences, 1999-04, Vol.8 (1), p.67-73

1999

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Regulation of pathways within cultured epithelial cells for the transcytosis of a basal membrane-bound peroxidase-polylysine conjugate

Journal of cell science, 1993-12, Vol.106 (4), p.1313-1321

1993

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Advances in the study of drug metabolism - symposium report of the 12th Meeting of the International Society for the Study of Xenobiotics (ISSX)

Drug metabolism reviews, 2020-07, Vol.52 (3), p.395-407

2020

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Functional assessment of multiple P-glycoprotein (P-gp) probe substrates: influence of cell line and modulator concentration on P-gp activity

Drug metabolism and disposition, 2005-11, Vol.33 (11), p.1679-1687

2005

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Transepithelial transport of tyramine across filter-grown MDCK cells via a poly(D-lysine) carrier

Pharmaceutical research, 1994-09, Vol.11 (9), p.1250-1256

1994

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Polarity in the transcytotic processing of apical and basal membrane-bound peroxidase-polylysine conjugates in MDCK cells

Journal of cellular physiology, 1992-02, Vol.150 (2), p.283-290

1992

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Oligopeptide transporter mediated uptake and transport of d-Asp(OBzl)-Ala, d-Glu(OBzl)-Ala, and d-Ser(Bzl)-Ala in filter-grown Caco-2 monolayers

International journal of pharmaceutics, 1998-11, Vol.174 (1), p.223-232

1998

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ITC Recommendations for Transporter Kinetic Parameter Estimation and Translational Modeling of Transport-Mediated PK and DDIs in Humans : Transporters in Drug Development and Clinical Pharmacology

Clinical pharmacology and therapeutics, 2013, Vol.94 (1), p.64-79

2013

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Influence of oligopeptide transporter binding affinity upon uptake and transport of d-Asp(OBzl)-Ala and Asp(OBzl)-Sar in filter-grown Caco-2 monolayers

International journal of pharmaceutics, 1997-10, Vol.156 (2), p.219-228

1997

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β-Carboxylic acid esterified d-Asp-Ala retains a high affinity for the oligopeptide transporter in Caco-2 monolayers

International journal of pharmaceutics, 1997-01, Vol.146 (2), p.205-212

1997

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Optimized conditions for MDCK permeability and turbidimetric solubility studies using compounds representative of BCS classes I–IV

European journal of pharmaceutical sciences, 2002-05, Vol.15 (4), p.331-340

2002

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Experience with the Artificial Urinary Sphincter at Michigan

The Journal of urology, 1976-10, Vol.116 (4), p.496-500

1976

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A clinical study investigating the pharmacokinetic interaction between NN703 (tabimorelin), a potential inhibitor of CYP3A4 activity, and midazolam, a CYP3A4 substrate

European journal of clinical pharmacology, 2003-02, Vol.58 (10), p.683-688

2003

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Cancer Genetics and Genomics for Personalized Medicine

1, 2017

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The orphan tyrosine kinase receptor, ROR2, mediates Wnt5A signaling in metastatic melanoma

Oncogene, 2010-01, Vol.29 (1), p.34-44

2010

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Confirming genes influencing risk to cleft lip with/without cleft palate in a case–parent trio study

Human genetics, 2013-07, Vol.132 (7), p.771-781

2013

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Transporters in Drug Development: 2018 ITC Recommendations for Transporters of Emerging Clinical Importance

Clinical pharmacology and therapeutics, 2018-11, Vol.104 (5), p.890-899

2018

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Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis

Nature biotechnology, 2013-02, Vol.31 (2), p.142-147

2013

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Ten things to know about ten cardiovascular disease risk factors

American journal of preventive cardiology, 2021-03, Vol.5, p.100149, Article 100149

2021

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ITC Recommendations for Transporter Kinetic Parameter Estimation and Translational Modeling of Transport-Mediated PK and DDIs in Humans

Pharmacokinetic Evaluation of a Drug Transporter Cocktail Consisting of Digoxin, Furosemide, Metformin, and Rosuvastatin

Effect of its deaminated metabolite, 2′,2′-difluorodeoxyuridine, on the transport and toxicity of gemcitabine in HeLa cells

Brefeldin A enhances receptor-mediated transcytosis of transferrin in filter-grown Madin-Darby canine kidney cells

Dipeptide model prodrugs for the intestinal oligopeptide transporter. Affinity for and transport via hPepT1 in the human intestinal Caco-2 cell line

Stability and in vitro metabolism of dipeptide model prodrugs with affinity for the oligopeptide transporter

Stability, metabolism and transport of d-Asp(OBzl)–Ala — a model prodrug with affinity for the oligopeptide transporter

Regulation of pathways within cultured epithelial cells for the transcytosis of a basal membrane-bound peroxidase-polylysine conjugate

Advances in the study of drug metabolism - symposium report of the 12th Meeting of the International Society for the Study of Xenobiotics (ISSX)

Functional assessment of multiple P-glycoprotein (P-gp) probe substrates: influence of cell line and modulator concentration on P-gp activity

Transepithelial transport of tyramine across filter-grown MDCK cells via a poly(D-lysine) carrier

Polarity in the transcytotic processing of apical and basal membrane-bound peroxidase-polylysine conjugates in MDCK cells

Oligopeptide transporter mediated uptake and transport of d-Asp(OBzl)-Ala, d-Glu(OBzl)-Ala, and d-Ser(Bzl)-Ala in filter-grown Caco-2 monolayers

ITC Recommendations for Transporter Kinetic Parameter Estimation and Translational Modeling of Transport-Mediated PK and DDIs in Humans : Transporters in Drug Development and Clinical Pharmacology

Influence of oligopeptide transporter binding affinity upon uptake and transport of d-Asp(OBzl)-Ala and Asp(OBzl)-Sar in filter-grown Caco-2 monolayers

β-Carboxylic acid esterified d-Asp-Ala retains a high affinity for the oligopeptide transporter in Caco-2 monolayers

Optimized conditions for MDCK permeability and turbidimetric solubility studies using compounds representative of BCS classes I–IV

Experience with the Artificial Urinary Sphincter at Michigan

A clinical study investigating the pharmacokinetic interaction between NN703 (tabimorelin), a potential inhibitor of CYP3A4 activity, and midazolam, a CYP3A4 substrate

Cancer Genetics and Genomics for Personalized Medicine

The orphan tyrosine kinase receptor, ROR2, mediates Wnt5A signaling in metastatic melanoma

Confirming genes influencing risk to cleft lip with/without cleft palate in a case–parent trio study

Transporters in Drug Development: 2018 ITC Recommendations for Transporters of Emerging Clinical Importance

Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis

Ten things to know about ten cardiovascular disease risk factors

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