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Identification of Adenine and Benzimidazole Nucleosides as Potent Human Concentrative Nucleoside Transporter 2 Inhibitors: Potential Treatment for Hyperuricemia and Gout

Journal of medicinal chemistry, 2016-04, Vol.59 (8), p.3719-3731

2016

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Identification of 8‑Aminoadenosine Derivatives as a New Class of Human Concentrative Nucleoside Transporter 2 Inhibitors

ACS medicinal chemistry letters, 2015-03, Vol.6 (3), p.244-248

2015

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Novel pyrazolo[1,5-a]pyridines as orally active EP1 receptor antagonists: Synthesis, structure-activity relationship studies, and biological evaluation

Bioorganic & medicinal chemistry, 2017-05, Vol.25 (9), p.2635-2642

2017

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Identification of novel 1,2,3,6-tetrahydropyridyl-substituted benzo[d]thiazoles: Lead generation and optimization toward potent and orally active EP1 receptor antagonists

Bioorganic & medicinal chemistry, 2017-07, Vol.25 (13), p.3406-3430

2017

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Discovery of remogliflozin etabonate: A potent and highly selective SGLT2 inhibitor

Bioorganic & medicinal chemistry, 2021-03, Vol.34, p.116033-116033, Article 116033

2021

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Discovery of novel pyrazolo[1,5-a]pyridine-based EP1 receptor antagonists by scaffold hopping: Design, synthesis, and structure-activity relationships

Bioorganic & medicinal chemistry letters, 2017-09, Vol.27 (17), p.4044-4050

2017

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Identification of novel 1,2,3,6-tetrahydropyridyl-substituted benzo[d]thiazoles: Lead generation and optimization toward potent and orally active EP 1 receptor antagonists

Bioorganic & medicinal chemistry, 2017-07, Vol.25 (13), p.3406-3430

2017

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Novel pyrazolo[1,5-a]pyridines as orally active EP 1 receptor antagonists: Synthesis, structure-activity relationship studies, and biological evaluation

Bioorganic & medicinal chemistry, 2017-05, Vol.25 (9), p.2635-2642

2017

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Hypouricemic effects of novel concentrative nucleoside transporter 2 inhibitors through suppressing intestinal absorption of purine nucleosides

European journal of pharmacology, 2012-09, Vol.690 (1-3), p.183-191

2012

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Discovery of novel pyrazolo[1,5-a]pyridine-based EP 1 receptor antagonists by scaffold hopping: Design, synthesis, and structure-activity relationships

Bioorganic & medicinal chemistry letters, 2017-09, Vol.27 (17), p.4044

2017

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A Concise and Enantioselective Synthesis of a C-6 O-Acyl Side Chain Equivalent of Zaragozic Acid A

Chemical and Pharmaceutical Bulletin, 1999/09/15, Vol.47(9), pp.1330-1333

1999

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Synthesis of Adenophostin Analogues Lacking the Adenine Moiety as Novel Potent IP3 Receptor Ligands: Some Structural Requirements for the Significant Activity of Adenophostin A

Journal of organic chemistry, 1998-11, Vol.63 (24), p.8815-8824

1998

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Inositol 1,4,5-trisphosphate and adenophostin analogues induce responses in turtle olfactory sensory neurons

The European journal of neuroscience, 2000-02, Vol.12 (2), p.606-612

2000

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Synthesis of Adenophostin Analogues Lacking the Adenine Moiety as Novel Potent IP 3 Receptor Ligands: Some Structural Requirements for the Significant Activity of Adenophostin A

Journal of organic chemistry, 1998-11, Vol.63 (24), p.8815-8824

1998

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Synthesis of 1-0-[(3S,4R)-3-hydroxytetrahydrofuran-4-yl]-α-D-glucopyranoside 3,4,3′-trisphosphate as a novel potent IP3 receptor ligand

Tetrahedron letters, 1998-07, Vol.39 (28), p.5065-5068

1998

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ChemInform Abstract: A Concise and Enantioselective Synthesis of a C-6 O-Acyl Side Chain Equivalent of Zaragozic Acid A

ChemInform, 2000-03, Vol.31 (11), p.no-no

2000

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ChemInform Abstract: A New Method for Oxidation of Various Alcohols to the Corresponding Carbonyl Compounds by Using N-t-Butylbenzenesulfinimidoyl Chloride

ChemInform, 2002-06, Vol.33 (24), p.no-no

2002

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Identification of Adenine and Benzimidazole Nucleosides as Potent Human Concentrative Nucleoside Transporter 2 Inhibitors: Potential Treatment for Hyperuricemia and Gout

Identification of 8‑Aminoadenosine Derivatives as a New Class of Human Concentrative Nucleoside Transporter 2 Inhibitors

Novel pyrazolo[1,5-a]pyridines as orally active EP1 receptor antagonists: Synthesis, structure-activity relationship studies, and biological evaluation

Identification of novel 1,2,3,6-tetrahydropyridyl-substituted benzo[d]thiazoles: Lead generation and optimization toward potent and orally active EP1 receptor antagonists

Discovery of remogliflozin etabonate: A potent and highly selective SGLT2 inhibitor

Discovery of novel pyrazolo[1,5-a]pyridine-based EP1 receptor antagonists by scaffold hopping: Design, synthesis, and structure-activity relationships

Identification of novel 1,2,3,6-tetrahydropyridyl-substituted benzo[d]thiazoles: Lead generation and optimization toward potent and orally active EP 1 receptor antagonists

Novel pyrazolo[1,5-a]pyridines as orally active EP 1 receptor antagonists: Synthesis, structure-activity relationship studies, and biological evaluation

Hypouricemic effects of novel concentrative nucleoside transporter 2 inhibitors through suppressing intestinal absorption of purine nucleosides

Discovery of novel pyrazolo[1,5-a]pyridine-based EP 1 receptor antagonists by scaffold hopping: Design, synthesis, and structure-activity relationships

A Concise and Enantioselective Synthesis of a C-6 O-Acyl Side Chain Equivalent of Zaragozic Acid A

Synthesis of Adenophostin Analogues Lacking the Adenine Moiety as Novel Potent IP3 Receptor Ligands: Some Structural Requirements for the Significant Activity of Adenophostin A

Inositol 1,4,5-trisphosphate and adenophostin analogues induce responses in turtle olfactory sensory neurons

Synthesis of Adenophostin Analogues Lacking the Adenine Moiety as Novel Potent IP 3 Receptor Ligands: Some Structural Requirements for the Significant Activity of Adenophostin A

Synthesis of 1-0-[(3S,4R)-3-hydroxytetrahydrofuran-4-yl]-α-D-glucopyranoside 3,4,3′-trisphosphate as a novel potent IP3 receptor ligand

ChemInform Abstract: A Concise and Enantioselective Synthesis of a C-6 O-Acyl Side Chain Equivalent of Zaragozic Acid A

ChemInform Abstract: A New Method for Oxidation of Various Alcohols to the Corresponding Carbonyl Compounds by Using N-t-Butylbenzenesulfinimidoyl Chloride

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