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Guanosine Mechanisms of Action: Toward Molecular Targets

Frontiers in pharmacology, 2021-03, Vol.12, p.653146-653146

2021

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Short bouts of mild-intensity physical exercise improve spatial learning and memory in aging rats: Involvement of hippocampal plasticity via AKT, CREB and BDNF signaling

Mechanisms of ageing and development, 2011-11, Vol.132 (11-12), p.560-567

2011

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Guanosine controls inflammatory pathways to afford neuroprotection of hippocampal slices under oxygen and glucose deprivation conditions

Journal of neurochemistry, 2013-08, Vol.126 (4), p.437-450

2013

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Editorial: Insights in neuroenergetics, nutrition and brain health: 2023

Frontiers in neuroscience, 2023-12, Vol.17, p.1331872-1331872

2023

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Neuromodulatory Effects of Guanine-Based Purines in Health and Disease

Frontiers in cellular neuroscience, 2018-10, Vol.12, p.376-376

2018

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The lectin DrfL inhibits cell migration, adhesion and triggers autophagy-dependent cell death in glioma cells

Glycoconjugate journal, 2023-02, Vol.40 (1), p.47

2023

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The intranasal administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): a new rodent model to test palliative and neuroprotective agents for Parkinson's disease

Current pharmaceutical design, 2011-02, Vol.17 (5), p.489-507

2011

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Melatonin protects against oxygen and glucose deprivation by decreasing extracellular glutamate and Nox-derived ROS in rat hippocampal slices

Neurotoxicology (Park Forest South), 2016-12, Vol.57, p.61-68

2016

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Ferulic acid exerts antidepressant-like effect in the tail suspension test in mice: Evidence for the involvement of the serotonergic system

European journal of pharmacology, 2012-03, Vol.679 (1-3), p.68-74

2012

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Lithium and valproate prevent olfactory discrimination and short-term memory impairments in the intranasal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) rat model of Parkinson's disease

Behavioural brain research, 2012-04, Vol.229 (1), p.208-215

2012

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Atorvastatin improves cognitive, emotional and motor impairments induced by intranasal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration in rats, an experimental model of Parkinson's disease

Brain research, 2013-06, Vol.1513, p.103-116

2013

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Atorvastatin prevents hippocampal cell death, neuroinflammation and oxidative stress following amyloid-β1―40 administration in mice: Evidence for dissociation between cognitive deficits and neuronal damage

Experimental neurology, 2010-12, Vol.226 (2), p.274-284

2010

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Adenosine A1-A2A Receptor-Receptor Interaction: Contribution to Guanosine-Mediated Effects

Cells (Basel, Switzerland), 2019-12, Vol.8 (12), p.1630

2019

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Targeting the guanine-based purinergic system in Alzheimer's disease

Neural regeneration research, 2017-02, Vol.12 (2), p.212-213

2017

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Antiparkinsonian Efficacy of Guanosine in Rodent Models of Movement Disorder

Frontiers in pharmacology, 2017-10, Vol.8, p.700-700

2017

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Adenosine A1 receptor activation modulates N-methyl-d-aspartate (NMDA) preconditioning phenotype in the brain

Behavioural brain research, 2015-04, Vol.282, p.103-110

2015

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Guanosine increases global SUMO1‐ylation in the hippocampus of young and aged mice and improves the short‐term memory of young mice

Journal of neurochemistry, 2024-08, Vol.168 (8), p.1503-1513

2024

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Atorvastatin Prevents Hippocampal Cell Death due to Quinolinic Acid-Induced Seizures in Mice by Increasing Akt Phosphorylation and Glutamate Uptake

Neurotoxicity research, 2009-08, Vol.16 (2), p.106-115

2009

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The impact of purine nucleosides on neuroplasticity in the adult brain

Purinergic signalling, 2024-02

2024

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Both Creatine and Its Product Phosphocreatine Reduce Oxidative Stress and Afford Neuroprotection in an In Vitro Parkinson’s Model

ASN neuro, 2014-10, Vol.6 (6), p.175909141455494

2014

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In vitro oxygen-glucose deprivation to study ischemic cell death

Methods in molecular biology (Clifton, N.J.), 2015, Vol.1254, p.197

2015

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Anxiogenic-like profile of Wistar adult rats based on the pilocarpine model: an animal model for trait anxiety?

Psychopharmacology, 2013-05, Vol.227 (2), p.209-219

2013

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Neuroprotection induced by NMDA preconditioning as a strategy to understand brain tolerance mechanism

Neural regeneration research, 2015-04, Vol.10 (4), p.542-543

2015

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Mechanism of guanosine-induced neuroprotection in rat hippocampal slices submitted to oxygen–glucose deprivation

Neurochemistry international, 2008-02, Vol.52 (3), p.411-418

2008

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Guanosine prevents oxidative damage and glutamate uptake impairment induced by oxygen/glucose deprivation in cortical astrocyte cultures: involvement of A1 and A2A adenosine receptors and PI3K, MEK, and PKC pathways

Purinergic signalling, 2019-12, Vol.15 (4), p.465-476

2019

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Guanosine Mechanisms of Action: Toward Molecular Targets

Short bouts of mild-intensity physical exercise improve spatial learning and memory in aging rats: Involvement of hippocampal plasticity via AKT, CREB and BDNF signaling

Guanosine controls inflammatory pathways to afford neuroprotection of hippocampal slices under oxygen and glucose deprivation conditions

Editorial: Insights in neuroenergetics, nutrition and brain health: 2023

Neuromodulatory Effects of Guanine-Based Purines in Health and Disease

The lectin DrfL inhibits cell migration, adhesion and triggers autophagy-dependent cell death in glioma cells

The intranasal administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): a new rodent model to test palliative and neuroprotective agents for Parkinson's disease

Melatonin protects against oxygen and glucose deprivation by decreasing extracellular glutamate and Nox-derived ROS in rat hippocampal slices

Ferulic acid exerts antidepressant-like effect in the tail suspension test in mice: Evidence for the involvement of the serotonergic system

Lithium and valproate prevent olfactory discrimination and short-term memory impairments in the intranasal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) rat model of Parkinson's disease

Atorvastatin improves cognitive, emotional and motor impairments induced by intranasal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration in rats, an experimental model of Parkinson's disease

Atorvastatin prevents hippocampal cell death, neuroinflammation and oxidative stress following amyloid-β1―40 administration in mice: Evidence for dissociation between cognitive deficits and neuronal damage

Adenosine A1-A2A Receptor-Receptor Interaction: Contribution to Guanosine-Mediated Effects

Targeting the guanine-based purinergic system in Alzheimer's disease

Antiparkinsonian Efficacy of Guanosine in Rodent Models of Movement Disorder

Adenosine A1 receptor activation modulates N-methyl-d-aspartate (NMDA) preconditioning phenotype in the brain

Guanosine increases global SUMO1‐ylation in the hippocampus of young and aged mice and improves the short‐term memory of young mice

Atorvastatin Prevents Hippocampal Cell Death due to Quinolinic Acid-Induced Seizures in Mice by Increasing Akt Phosphorylation and Glutamate Uptake

The impact of purine nucleosides on neuroplasticity in the adult brain

Both Creatine and Its Product Phosphocreatine Reduce Oxidative Stress and Afford Neuroprotection in an In Vitro Parkinson’s Model

In vitro oxygen-glucose deprivation to study ischemic cell death

Anxiogenic-like profile of Wistar adult rats based on the pilocarpine model: an animal model for trait anxiety?

Neuroprotection induced by NMDA preconditioning as a strategy to understand brain tolerance mechanism

Mechanism of guanosine-induced neuroprotection in rat hippocampal slices submitted to oxygen–glucose deprivation

Guanosine prevents oxidative damage and glutamate uptake impairment induced by oxygen/glucose deprivation in cortical astrocyte cultures: involvement of A1 and A2A adenosine receptors and PI3K, MEK, and PKC pathways

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