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Voices of biotech leaders

Nature biotechnology, 2021-06, Vol.39 (6), p.654-660

2021

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Publisher Correction: Voices of biotech leaders

Nature biotechnology, 2021-08, Vol.39 (8), p.1017-1017

2021

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Inhibition of Human Prolyl Oligopeptidase Activity by the Cyclotide Psysol 2 Isolated from Psychotria solitudinum

Journal of natural products (Washington, D.C.), 2015-05, Vol.78 (5), p.1073-1082

2015

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Small Peptide Inhibitors Disrupt a High-Affinity Interaction between Cytoplasmic Dynein and a Viral Cargo Protein

Journal of Virology, 2010-10, Vol.84 (20), p.10792-10801

2010

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Peptidomimetics designed to bind to RAS effector domain are promising cancer therapeutic compounds

Scientific reports, 2022-09, Vol.12 (1), p.15810-15810, Article 15810

2022

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Inhibition of Prolyl Oligopeptidase Restores Prohibitin 2 Levels in Psychosis Models: Relationship to Cognitive Deficits in Schizophrenia

International journal of molecular sciences, 2023-03, Vol.24 (7), p.6016

2023

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The glial phosphorylase of glycogen isoform is reduced in the dorsolateral prefrontal cortex in chronic schizophrenia

Schizophrenia research, 2016-11, Vol.177 (1-3), p.37-43

2016

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NMR analysis of G-protein βγ subunit complexes reveals a dynamic Gα-Gβγ subunit interface and multiple protein recognition modes

Proceedings of the National Academy of Sciences - PNAS, 2010, Vol.107 (2), p.639-644

2010

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Targeted Covalent Inhibition of Prolyl Oligopeptidase (POP): Discovery of Sulfonylfluoride Peptidomimetics

Cell chemical biology, 2018-08, Vol.25 (8), p.1031-1037.e4

2018

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The matrix metalloproteinase inhibitor IPR-179 has antiseizure and antiepileptogenic effects

The Journal of clinical investigation, 2021-01, Vol.131 (1), p.1-16

2021

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Unveiling Prolyl Oligopeptidase Ligand Migration by Comprehensive Computational Techniques

Biophysical journal, 2015-01, Vol.108 (1), p.116-125

2015

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NMR studies of protein-ligand interactions

Methods in molecular biology (Clifton, N.J.), 2012-01, Vol.831, p.233

2012

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Diketopiperazines as a Tool for the Study of Transport across the Blood−Brain Barrier (BBB) and Their Potential Use as BBB-Shuttles

Journal of the American Chemical Society, 2007-09, Vol.129 (38), p.11802-11813

2007

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The prolyl oligopeptidase inhibitor IPR19 ameliorates cognitive deficits in mouse models of schizophrenia

European neuropsychopharmacology, 2017-02, Vol.27 (2), p.180-191

2017

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Baicalin, a prodrug able to reach the CNS, is a prolyl oligopeptidase inhibitor

Bioorganic & medicinal chemistry, 2008-08, Vol.16 (15), p.7516-7524

2008

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Design and synthesis of selective and blood-brain barrier-permeable hydroxamate-based gelatinase inhibitors

Bioorganic chemistry, 2020-01, Vol.94, p.103365, Article 103365

2020

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Increased SP4 and SP1 transcription factor expression in the postmortem hippocampus of chronic schizophrenia

Journal of psychiatric research, 2014-11, Vol.58, p.189-196

2014

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Analyzing slowly exchanging protein conformations by ion mobility mass spectrometry: study of the dynamic equilibrium of prolyl oligopeptidase

Journal of mass spectrometry., 2016-07, Vol.51 (7), p.504-511

2016

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Molecular basis for the protective effects of low-density lipoprotein receptor-related protein 1 (LRP1)-derived peptides against LDL aggregation

Biochimica et biophysica acta. Biomembranes, 2019-07, Vol.1861 (7), p.1302-1316

2019

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Low molecular weight inhibitors of Prolyl Oligopeptidase: a review of compounds patented from 2003 to 2010

Expert opinion on therapeutic patents, 2011-07, Vol.21 (7), p.1023-1044

2011

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Seasonal variability of the vitamin C content of fresh fruits and vegetables in a local retail market

Journal of the science of food and agriculture, 2018-08, Vol.98 (11), p.4191-4204

2018

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Active-Site-Directed Inhibitors of Prolyl Oligopeptidase Abolish Its Conformational Dynamics

Chembiochem : a European journal of chemical biology, 2016-05, Vol.17 (10), p.913-917

2016

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A signaling mechanism coupling netrin-1/deleted in colorectal cancer chemoattraction to SNARE-mediated exocytosis in axonal growth cones

The Journal of neuroscience, 2011-10, Vol.31 (41), p.14463-14480

2011

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Towards the identification of unknown neuropeptide precursor-processing enzymes: Design and synthesis of a new family of dipeptidyl phosphonate activity probes for substrate-based protease identification

Bioorganic & medicinal chemistry, 2010-12, Vol.18 (23), p.8350-8355

2010

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Applications and future of ion mobility mass spectrometry in structural biology

New journal of chemistry, 2013-01, Vol.37 (5), p.1283-1289

2013

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Science & Technology
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Voices of biotech leaders

Publisher Correction: Voices of biotech leaders

Inhibition of Human Prolyl Oligopeptidase Activity by the Cyclotide Psysol 2 Isolated from Psychotria solitudinum

Small Peptide Inhibitors Disrupt a High-Affinity Interaction between Cytoplasmic Dynein and a Viral Cargo Protein

Peptidomimetics designed to bind to RAS effector domain are promising cancer therapeutic compounds

Inhibition of Prolyl Oligopeptidase Restores Prohibitin 2 Levels in Psychosis Models: Relationship to Cognitive Deficits in Schizophrenia

The glial phosphorylase of glycogen isoform is reduced in the dorsolateral prefrontal cortex in chronic schizophrenia

NMR analysis of G-protein βγ subunit complexes reveals a dynamic Gα-Gβγ subunit interface and multiple protein recognition modes

Targeted Covalent Inhibition of Prolyl Oligopeptidase (POP): Discovery of Sulfonylfluoride Peptidomimetics

The matrix metalloproteinase inhibitor IPR-179 has antiseizure and antiepileptogenic effects

Unveiling Prolyl Oligopeptidase Ligand Migration by Comprehensive Computational Techniques

NMR studies of protein-ligand interactions

Diketopiperazines as a Tool for the Study of Transport across the Blood−Brain Barrier (BBB) and Their Potential Use as BBB-Shuttles

The prolyl oligopeptidase inhibitor IPR19 ameliorates cognitive deficits in mouse models of schizophrenia

Baicalin, a prodrug able to reach the CNS, is a prolyl oligopeptidase inhibitor

Design and synthesis of selective and blood-brain barrier-permeable hydroxamate-based gelatinase inhibitors

Increased SP4 and SP1 transcription factor expression in the postmortem hippocampus of chronic schizophrenia

Analyzing slowly exchanging protein conformations by ion mobility mass spectrometry: study of the dynamic equilibrium of prolyl oligopeptidase

Molecular basis for the protective effects of low-density lipoprotein receptor-related protein 1 (LRP1)-derived peptides against LDL aggregation

Low molecular weight inhibitors of Prolyl Oligopeptidase: a review of compounds patented from 2003 to 2010

Seasonal variability of the vitamin C content of fresh fruits and vegetables in a local retail market

Active-Site-Directed Inhibitors of Prolyl Oligopeptidase Abolish Its Conformational Dynamics

A signaling mechanism coupling netrin-1/deleted in colorectal cancer chemoattraction to SNARE-mediated exocytosis in axonal growth cones

Towards the identification of unknown neuropeptide precursor-processing enzymes: Design and synthesis of a new family of dipeptidyl phosphonate activity probes for substrate-based protease identification

Applications and future of ion mobility mass spectrometry in structural biology

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