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Non-competitive AMPA antagonists of 2,3-benzodiazepine type

Current pharmaceutical design, 2002-05, Vol.8 (10), p.913-939

2002

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Predictive validity of endpoints used in electrophysiological modelling of migraine in the trigeminovascular system

Brain research, 2015-11, Vol.1625, p.287-300

2015

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Blockers of voltage-gated sodium channels for the treatment of central nervous system diseases

Recent patents on CNS drug discovery, 2007-01, Vol.2 (1), p.57-78

2007

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Tolperisone-type drugs inhibit spinal reflexes via blockade of voltage-gated sodium and calcium channels

The Journal of pharmacology and experimental therapeutics, 2005-12, Vol.315 (3), p.1237-1246

2005

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Simple pharmacological test battery to assess efficacy and side effect profile of centrally acting muscle relaxant drugs

Journal of pharmacological and toxicological methods, 2005-09, Vol.52 (2), p.264-273

2005

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Functional characterization of sodium channel blockers by membrane potential measurements in cerebellar neurons: Prediction of compound preference for the open/inactivated state

Neurochemistry international, 2006-11, Vol.49 (6), p.593-604

2006

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Recent advancements in anti-migraine drug research: focus on attempts to decrease neuronal hyperexcitability

Recent patents on CNS drug discovery, 2009-01, Vol.4 (1), p.14-36

2009

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Voltage-gated sodium channel blockers, 2001-2006: An overview

Medicinal chemistry research, 2008-06, Vol.17 (2-7), p.356-368

2008

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NR2B containing NMDA receptor dependent windup of single spinal neurons

Neuropharmacology, 2004, Vol.46 (1), p.23-30

2004

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Concerted action of antiepileptic and antidepressant agents to depress spinal neurotransmission: Possible use in the therapy of spasticity and chronic pain

Neurochemistry international, 2007-03, Vol.50 (4), p.642-652

2007

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Participation of AMPA- and NMDA-type excitatory amino acid receptors in the spinal reflex transmission, in rat

Brain research bulletin, 2003-04, Vol.60 (1), p.81-91

2003

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Protective effect of the antiepileptic drug candidate talampanel against AMPA-induced striatal neurotoxicity in neonatal rats

Brain research bulletin, 2002-10, Vol.59 (1), p.35-40

2002

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Bicarbonate and thiocyanate ions affect the gating of γ-aminobutyric acidA receptors in cultured rat cortical cells

Neuroscience letters, 2001-10, Vol.311 (3), p.169-172

2001

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Characterization of the inhibitory action of compounds on NaV1.2 sodium channels by using an automated patch-clamp assay

Frontiers in neuroscience, 2010, Vol.4

István, Tarnawa

2010

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Activity of 2,3-benzodiazepines at native rat and recombinant human glutamate receptors in vitro : Stereospecificity and selectivity profiles

Neuropharmacology, 1996-01, Vol.35 (12), p.1689-1702

1996

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Measurement of state-dependent action of sodium channel inhibitors

Frontiers in systems neuroscience, 2009, Vol.3

Istvan, Tarnawa

2009

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Improved-throughput testing of drugs acting on ion channels: application of the automated patch clamp technique

Frontiers in systems neuroscience, 2009, Vol.3

Istvan, Tarnawa

2009

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New non competitive AMPA antagonists

Bioorganic & medicinal chemistry, 2000-08, Vol.8 (8), p.2127-2143

2000

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Exploring the role of sodium channel inhibitors in neurological and psychiatric disorders

Drugs of the future, 2012-07, Vol.37 (7), p.499

Tarnawa, I.

2012

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NR2B receptors are involved in the mediation of spinal segmental reflex potentials but not in the cumulative motoneuronal depolarization in vitro

Brain research bulletin, 2004-08, Vol.64 (2), p.133-138

2004

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Exploring the role of sodium channel inhibitors in neurological and psychiatric disorders

Drugs of the future, 2012, Vol.37 (7), p.499

Tarnawa, I.

2012

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Bicarbonate and thiocyanate ions affect the gating of gamma-aminobutyric acid(A) receptors in cultured rat cortical cells

Neuroscience letters, 2001-10, Vol.311 (3), p.169-172

2001

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Structural analogues of some highly active non-competitive AMPA antagonists

Bioorganic & medicinal chemistry letters, 2000-05, Vol.10 (9), p.899-902

2000

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Electrophysiological studies with a 2,3-benzodiazepine muscle relaxant: GYKI 52466

European journal of pharmacology, 1989-08, Vol.167 (2), p.193-199

1989

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AMPA receptor antagonists, GYKI 52466 and NBQX, do not block the induction of long-term potentiation at therapeutically relevant concentrations

Brain research bulletin, 2000-08, Vol.52 (6), p.511-517

2000

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Non-competitive AMPA antagonists of 2,3-benzodiazepine type

Predictive validity of endpoints used in electrophysiological modelling of migraine in the trigeminovascular system

Blockers of voltage-gated sodium channels for the treatment of central nervous system diseases

Tolperisone-type drugs inhibit spinal reflexes via blockade of voltage-gated sodium and calcium channels

Simple pharmacological test battery to assess efficacy and side effect profile of centrally acting muscle relaxant drugs

Functional characterization of sodium channel blockers by membrane potential measurements in cerebellar neurons: Prediction of compound preference for the open/inactivated state

Recent advancements in anti-migraine drug research: focus on attempts to decrease neuronal hyperexcitability

Voltage-gated sodium channel blockers, 2001-2006: An overview

NR2B containing NMDA receptor dependent windup of single spinal neurons

Concerted action of antiepileptic and antidepressant agents to depress spinal neurotransmission: Possible use in the therapy of spasticity and chronic pain

Participation of AMPA- and NMDA-type excitatory amino acid receptors in the spinal reflex transmission, in rat

Protective effect of the antiepileptic drug candidate talampanel against AMPA-induced striatal neurotoxicity in neonatal rats

Bicarbonate and thiocyanate ions affect the gating of γ-aminobutyric acidA receptors in cultured rat cortical cells

Characterization of the inhibitory action of compounds on NaV1.2 sodium channels by using an automated patch-clamp assay

Activity of 2,3-benzodiazepines at native rat and recombinant human glutamate receptors in vitro : Stereospecificity and selectivity profiles

Measurement of state-dependent action of sodium channel inhibitors

Improved-throughput testing of drugs acting on ion channels: application of the automated patch clamp technique

New non competitive AMPA antagonists

Exploring the role of sodium channel inhibitors in neurological and psychiatric disorders

NR2B receptors are involved in the mediation of spinal segmental reflex potentials but not in the cumulative motoneuronal depolarization in vitro

Exploring the role of sodium channel inhibitors in neurological and psychiatric disorders

Bicarbonate and thiocyanate ions affect the gating of gamma-aminobutyric acid(A) receptors in cultured rat cortical cells

Structural analogues of some highly active non-competitive AMPA antagonists

Electrophysiological studies with a 2,3-benzodiazepine muscle relaxant: GYKI 52466

AMPA receptor antagonists, GYKI 52466 and NBQX, do not block the induction of long-term potentiation at therapeutically relevant concentrations

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