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Regulation of the ubiquitin-proteasome system and proteostasis with mTOR inhibition in cytochrome c oxidase deficiency

Free radical biology & medicine, 2024-06, Vol.218, p.41-41

2024

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Prospects for Prostate Cancer Chemotherapy: Cytotoxic Evaluation and Mechanistic Insights of Quinolinequinones with ADME/PK Profile

Biomedicines, 2024-06, Vol.12 (6), p.1241

2024

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Synergistic role of thymoquinone and 5-fluorouracil in U-251MG glioblastoma cell line

Türk biyokimya dergisi, 2024-02, Vol.49 (1), p.82-89

2024

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Cytotoxic activity of quinolinequinones in cancer: In vitro studies, molecular docking, and ADME/PK profiling

Chemical biology & drug design, 2023-11, Vol.102 (5), p.1133-1154

2023

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Analysis of Quinolinequinone Analogs with Promising Cytotoxic Activity against Breast Cancer

Chemistry & biodiversity, 2023-09, Vol.20 (9), p.e202300848-e202300848

2023

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Molecular Cardiotoxic Effects of Proteasome Inhibitors Carfilzomib and Ixazomib and Their Combination with Dexamethasone Involve Mitochondrial Dysregulation

Cardiovascular toxicology, 2023-04, Vol.23 (3-4), p.121-131

2023

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Ubiquitin proteasomal system is a potential target of the toxic effects of organophosphorus flame retardant triphenyl phosphate

Environmental toxicology and pharmacology, 2022-11, Vol.96, p.104005-104005, Article 104005

2022

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Evaluation of Cytotoxic Activity of Small Aminated Quinolinequinones In Vitro as Anti-Cancer Molecules

Medical sciences forum, 2022-11, Vol.14 (1), p.38

2022

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In Vitro and In Silico Study to Assess Toxic Mechanisms of Hybrid Molecules of Quinone-Benzocaine as Plastoquinone Analogues in Breast Cancer Cells

ACS omega, 2022-08, Vol.7 (34), p.30250-30264

2022

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Zoledronic acid‐induced oxidative damage and endoplasmic reticulum stress‐mediated apoptosis in human embryonic kidney (HEK‐293) cells

Journal of biochemical and molecular toxicology, 2022-08, Vol.36 (8), p.e23083-n/a

2022

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Exploring the Anticancer Effects of Brominated Plastoquinone Analogs with Promising Cytotoxic Activity in MCF-7 Breast Cancer Cells via Cell Cycle Arrest and Oxidative Stress Induction

Pharmaceuticals (Basel, Switzerland), 2022-06, Vol.15 (7), p.777

2022

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Promising Antibacterial and Antifungal Agents Based on Thiolated Vitamin K3 Analogs: Synthesis, Bioevaluation, Molecular Docking

Pharmaceuticals (Basel, Switzerland), 2022-05, Vol.15 (5), p.586

2022

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Determination of the Phototoxicity Potential of Commercially Available Tattoo Inks Using the 3T3-neutral Red Uptake Phototoxicity Test

Turkish journal of pharmaceutical sciences, 2022-02, Vol.19 (1), p.70-75

2022

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Eugenol aggravates UVA-induced cytotoxic and genotoxic response in HaCaT human keratinocytes

Journal of Research in Pharmacy, 2022, Vol.26 (2) (26 (2)), p.354-361

Tarbin JANNUZZI, Ayse

2022

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Anticancer agents based on Plastoquinone analogs with N-phenylpiperazine: Structure-activity relationship and mechanism of action in breast cancer cells

Chemico-biological interactions, 2021-11, Vol.349, p.109673, Article 109673

2021

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Interactome analysis of Bag-1 isoforms reveals novel interaction partners in endoplasmic reticulum-associated degradation

PloS one, 2021-08, Vol.16 (8), p.e0256640

2021

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Mitochondrial dynamics imbalance and mitochondrial dysfunction contribute to the molecular cardiotoxic effects of lenvatinib

Toxicology and applied pharmacology, 2021-07, Vol.423, p.115577-115577, Article 115577

2021

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Proteasomal System Related Stress Response in Different Cancer Cell Lines

Clinical and experimental health sciences (Online), 2021-03, Vol.11 (1), p.28-33

2021

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Extended regorafenib treatment can be linked with mitochondrial damage leading to cardiotoxicity

Toxicology letters, 2021-01, Vol.336, p.39-49

2021

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Synergistic Induction of Apoptosis by Quercetin and Curcumin in Chronic Myeloid Leukemia (K562) Cells: II. Signal Transduction Pathways Involved

Nutrition and cancer, 2021, Vol.73 (4), p.703-712

2021

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In vitro assessment of the cytotoxic, genotoxic and oxidative stress effects of the synthetic cannabinoid JWH-018 in human SH-SY5Y neuronal cells

Toxicology research (Cambridge), 2020-12, Vol.9 (6), p.734-740

2020

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Higher proteotoxic stress rather than mitochondrial damage is involved in higher neurotoxicity of bortezomib compared to carfilzomib

Redox biology, 2020-05, Vol.32, p.101502, Article 101502

2020

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Investigation of Antimicrobial, Antibiofilm, and Cytotoxic Effects of Straight-Chained Sulfanyl Members of Arylamino-1,4-naphthoquinones as Potential Antimicrobial Agents

European Journal of Biology, 2019-12, Vol.78 (2), p.117

2019

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Celastrol pretreatment as a therapeutic option against cisplatin-induced nephrotoxicity

Toxicology research (Cambridge), 2019-09, Vol.8 (5), p.723-73

2019

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Proteomic approach for understanding milder neurotoxicity of Carfilzomib against Bortezomib

Scientific reports, 2018-11, Vol.8 (1), p.16318-13, Article 16318

2018

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Regulation of the ubiquitin-proteasome system and proteostasis with mTOR inhibition in cytochrome c oxidase deficiency

Prospects for Prostate Cancer Chemotherapy: Cytotoxic Evaluation and Mechanistic Insights of Quinolinequinones with ADME/PK Profile

Synergistic role of thymoquinone and 5-fluorouracil in U-251MG glioblastoma cell line

Cytotoxic activity of quinolinequinones in cancer: In vitro studies, molecular docking, and ADME/PK profiling

Analysis of Quinolinequinone Analogs with Promising Cytotoxic Activity against Breast Cancer

Molecular Cardiotoxic Effects of Proteasome Inhibitors Carfilzomib and Ixazomib and Their Combination with Dexamethasone Involve Mitochondrial Dysregulation

Ubiquitin proteasomal system is a potential target of the toxic effects of organophosphorus flame retardant triphenyl phosphate

Evaluation of Cytotoxic Activity of Small Aminated Quinolinequinones In Vitro as Anti-Cancer Molecules

In Vitro and In Silico Study to Assess Toxic Mechanisms of Hybrid Molecules of Quinone-Benzocaine as Plastoquinone Analogues in Breast Cancer Cells

Zoledronic acid‐induced oxidative damage and endoplasmic reticulum stress‐mediated apoptosis in human embryonic kidney (HEK‐293) cells

Exploring the Anticancer Effects of Brominated Plastoquinone Analogs with Promising Cytotoxic Activity in MCF-7 Breast Cancer Cells via Cell Cycle Arrest and Oxidative Stress Induction

Promising Antibacterial and Antifungal Agents Based on Thiolated Vitamin K3 Analogs: Synthesis, Bioevaluation, Molecular Docking

Determination of the Phototoxicity Potential of Commercially Available Tattoo Inks Using the 3T3-neutral Red Uptake Phototoxicity Test

Eugenol aggravates UVA-induced cytotoxic and genotoxic response in HaCaT human keratinocytes

Anticancer agents based on Plastoquinone analogs with N-phenylpiperazine: Structure-activity relationship and mechanism of action in breast cancer cells

Interactome analysis of Bag-1 isoforms reveals novel interaction partners in endoplasmic reticulum-associated degradation

Mitochondrial dynamics imbalance and mitochondrial dysfunction contribute to the molecular cardiotoxic effects of lenvatinib

Proteasomal System Related Stress Response in Different Cancer Cell Lines

Extended regorafenib treatment can be linked with mitochondrial damage leading to cardiotoxicity

Synergistic Induction of Apoptosis by Quercetin and Curcumin in Chronic Myeloid Leukemia (K562) Cells: II. Signal Transduction Pathways Involved

In vitro assessment of the cytotoxic, genotoxic and oxidative stress effects of the synthetic cannabinoid JWH-018 in human SH-SY5Y neuronal cells

Higher proteotoxic stress rather than mitochondrial damage is involved in higher neurotoxicity of bortezomib compared to carfilzomib

Investigation of Antimicrobial, Antibiofilm, and Cytotoxic Effects of Straight-Chained Sulfanyl Members of Arylamino-1,4-naphthoquinones as Potential Antimicrobial Agents

Celastrol pretreatment as a therapeutic option against cisplatin-induced nephrotoxicity

Proteomic approach for understanding milder neurotoxicity of Carfilzomib against Bortezomib

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