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The circuitry of a master switch: Myod and the regulation of skeletal muscle gene transcription

Development (Cambridge), 2005-06, Vol.132 (12), p.2685-2695

Tapscott, Stephen J

2005

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Distinct Activities of Myf5 and MyoD Indicate Separate Roles in Skeletal Muscle Lineage Specification and Differentiation

Developmental cell, 2016-02, Vol.36 (4), p.375-385

2016

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Conserved roles of mouse DUX and human DUX4 in activating cleavage-stage genes and MERVL/HERVL retrotransposons

Nature genetics, 2017-06, Vol.49 (6), p.925-934

2017

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DUX4 Suppresses MHC Class I to Promote Cancer Immune Evasion and Resistance to Checkpoint Blockade

Developmental cell, 2019-09, Vol.50 (5), p.658-671.e7

2019

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DUX4-induced gene expression is the major molecular signature in FSHD skeletal muscle

Human molecular genetics, 2014-10, Vol.23 (20), p.5342-5352

2014

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DUX4-induced dsRNA and MYC mRNA stabilization activate apoptotic pathways in human cell models of facioscapulohumeral dystrophy

PLoS genetics, 2017-03, Vol.13 (3), p.e1006658-e1006658

2017

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MyoD and the transcriptional control of myogenesis

Seminars in cell & developmental biology, 2005-08, Vol.16 (4), p.585-595

2005

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Genome-wide transcription factor binding: beyond direct target regulation

Trends in genetics, 2011-04, Vol.27 (4), p.141-148

2011

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DUX4 Activates Germline Genes, Retroelements, and Immune Mediators: Implications for Facioscapulohumeral Dystrophy

Developmental cell, 2012-01, Vol.22 (1), p.38-51

2012

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Unifying Genetic Model for Facioscapulohumeral Muscular Dystrophy

Science (American Association for the Advancement of Science), 2010-09, Vol.329 (5999), p.1650-1653

2010

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Facioscapulohumeral dystrophy: incomplete suppression of a retrotransposed gene

PLoS genetics, 2010-10, Vol.6 (10), p.e1001181-e1001181

2010

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Single-cell RNA sequencing in facioscapulohumeral muscular dystrophy disease etiology and development

Human molecular genetics, 2019-04, Vol.28 (7), p.1064-1075

2019

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Facioscapulohumeral muscular dystrophy: the road to targeted therapies

Nature reviews. Neurology, 2023-02, Vol.19 (2), p.91

2023

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DUX4 binding to retroelements creates promoters that are active in FSHD muscle and testis

PLoS genetics, 2013-11, Vol.9 (11), p.e1003947-e1003947

2013

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MyoD inhibits Fstl1 and Utrn expression by inducing transcription of miR-206

The Journal of cell biology, 2006-10, Vol.175 (1), p.77-85

2006

Volltextzugriff (PDF)

The FSHD2 Gene SMCHD1 Is a Modifier of Disease Severity in Families Affected by FSHD1

American journal of human genetics, 2013-10, Vol.93 (4), p.744-751

2013

Volltextzugriff (PDF)

Reciprocal inhibition between Pax7 and muscle regulatory factors modulates myogenic cell fate determination

The Journal of cell biology, 2007-06, Vol.177 (5), p.769-779

2007

Volltextzugriff (PDF)

Intrinsic epigenetic regulation of the D4Z4 macrosatellite repeat in a transgenic mouse model for FSHD

PLoS genetics, 2013-04, Vol.9 (4), p.e1003415-e1003415

2013

Volltextzugriff (PDF)

DUX4-induced bidirectional HSATII satellite repeat transcripts form intranuclear double-stranded RNA foci in human cell models of FSHD

Human molecular genetics, 2019-12, Vol.28 (23), p.3997-4011

2019

Volltextzugriff (PDF)

p38 MAPK signaling regulates recruitment of Ash2L-containing methyltransferase complexes to specific genes during differentiation

Nature structural & molecular biology, 2007-12, Vol.14 (12), p.1150-1156

2007

Volltextzugriff (PDF)

Tissue-specific splicing of a ubiquitously expressed transcription factor is essential for muscle differentiation

Genes & development, 2013-06, Vol.27 (11), p.1247-1259

2013

Volltextzugriff (PDF)

Quantitative proteomics reveals key roles for post-transcriptional gene regulation in the molecular pathology of facioscapulohumeral muscular dystrophy

eLife, 2019-01, Vol.8

2019

Volltextzugriff (PDF)

Essential role for Dicer during skeletal muscle development

Developmental biology, 2007-11, Vol.311 (2), p.359-368

2007

Volltextzugriff (PDF)

The transcription factor DUX4 orchestrates translational reprogramming by broadly suppressing translation efficiency and promoting expression of DUX4-induced mRNAs

PLoS biology, 2023-09, Vol.21 (9), p.e3002317-e3002317

2023

Volltextzugriff (PDF)

A feedback loop between nonsense-mediated decay and the retrogene DUX4 in facioscapulohumeral muscular dystrophy

eLife, 2015-01, Vol.4

2015

Volltextzugriff (PDF)

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The circuitry of a master switch: Myod and the regulation of skeletal muscle gene transcription

Distinct Activities of Myf5 and MyoD Indicate Separate Roles in Skeletal Muscle Lineage Specification and Differentiation

Conserved roles of mouse DUX and human DUX4 in activating cleavage-stage genes and MERVL/HERVL retrotransposons

DUX4 Suppresses MHC Class I to Promote Cancer Immune Evasion and Resistance to Checkpoint Blockade

DUX4-induced gene expression is the major molecular signature in FSHD skeletal muscle

DUX4-induced dsRNA and MYC mRNA stabilization activate apoptotic pathways in human cell models of facioscapulohumeral dystrophy

MyoD and the transcriptional control of myogenesis

Genome-wide transcription factor binding: beyond direct target regulation

DUX4 Activates Germline Genes, Retroelements, and Immune Mediators: Implications for Facioscapulohumeral Dystrophy

Unifying Genetic Model for Facioscapulohumeral Muscular Dystrophy

Facioscapulohumeral dystrophy: incomplete suppression of a retrotransposed gene

Single-cell RNA sequencing in facioscapulohumeral muscular dystrophy disease etiology and development

Facioscapulohumeral muscular dystrophy: the road to targeted therapies

DUX4 binding to retroelements creates promoters that are active in FSHD muscle and testis

MyoD inhibits Fstl1 and Utrn expression by inducing transcription of miR-206

The FSHD2 Gene SMCHD1 Is a Modifier of Disease Severity in Families Affected by FSHD1

Reciprocal inhibition between Pax7 and muscle regulatory factors modulates myogenic cell fate determination

Intrinsic epigenetic regulation of the D4Z4 macrosatellite repeat in a transgenic mouse model for FSHD

DUX4-induced bidirectional HSATII satellite repeat transcripts form intranuclear double-stranded RNA foci in human cell models of FSHD

p38 MAPK signaling regulates recruitment of Ash2L-containing methyltransferase complexes to specific genes during differentiation

Tissue-specific splicing of a ubiquitously expressed transcription factor is essential for muscle differentiation

Quantitative proteomics reveals key roles for post-transcriptional gene regulation in the molecular pathology of facioscapulohumeral muscular dystrophy

Essential role for Dicer during skeletal muscle development

The transcription factor DUX4 orchestrates translational reprogramming by broadly suppressing translation efficiency and promoting expression of DUX4-induced mRNAs

A feedback loop between nonsense-mediated decay and the retrogene DUX4 in facioscapulohumeral muscular dystrophy

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