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Down for the count: The critical endpoint in ototoxicity remains the cytocochleogram

Journal of pharmacological and toxicological methods, 2017-11, Vol.88 (Pt 2), p.123-129

2017

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The failure to detect drug-induced sensory loss in standard preclinical studies

Journal of pharmacological and toxicological methods, 2015-07, Vol.74, p.53-74

2015

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Small Compartment Toxicity: CN VIII and Quality of Life: Hearing Loss, Tinnitus, and Balance Disorders

International journal of toxicology, 2017-01, Vol.36 (1), p.8-20

2017

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Utility of the auditory brainstem response evaluation in non-clinical drug safety evaluations

Journal of pharmacological and toxicological methods, 2015-09, Vol.75, p.111-117

2015

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Consideration of Potential Systemic Effects of Chronic Administrations in Auditory Studies

Journal of pharmacological and toxicological methods, 2017-11, Vol.88, p.194-194

2017

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An evaluation of staining procedures for cytocochleogram analysis of middle ear organ of corti surface preparations

Journal of pharmacological and toxicological methods, 2011-07, Vol.64 (1), p.e58-e58

2011

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Distortion Product Otoacoustic Emission Test is Not the Test to Use in Nonclinical Safety Assessment

International journal of toxicology, 2022-05, Vol.41 (3), p.243-252

2022

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Ototoxicity: The Radical Drum Beat and Rhythm of Cochlear Hair Cell Life and Death

International Journal of Toxicology, 2018-05, Vol.37 (3), p.195-206

2018

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OTO-104: a sustained-release dexamethasone hydrogel for the treatment of otic disorders

Otology & neurotology, 2011-01, Vol.32 (1), p.171

2011

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Challenging contemporary status on drug safety evaluation: A case for the implementation of ototoxicity screening in toxicology programs

Journal of pharmacological and toxicological methods, 2015-09, Vol.75, p.158-159

2015

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Identification of NOEL and NOAEL in functional safety (pharmacology) studies: A survey of a contract research organization master schedule

Journal of pharmacological and toxicological methods, 2018-09, Vol.93, p.159-160

2018

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Predicting the Need for a Tier II Ototoxicity Study From Early Renal Function Data

International Journal of Toxicology, 2019-07, Vol.38 (4), p.265-278

2019

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Relative equivalence of CNS safety (FOB) assessment outcomes in male and female Wistar-Han and Sprague-Dawley rats

Journal of pharmacological and toxicological methods, 2019-01, Vol.95, p.2-11

2019

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Auditory brainstem response evaluations in cynomolgus macaques: Considerations for anesthesia and waveform data collection and analysis

Journal of pharmacological and toxicological methods, 2016-09, Vol.81, p.335-335

2016

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Development and evaluation of a Middle Ear PinPort™ for use in otic histology studies

Journal of pharmacological and toxicological methods, 2016-09, Vol.81, p.338-338

2016

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Influence of stimulus parameters and speaker calibration on auditory threshold sensitivity

Journal of pharmacological and toxicological methods, 2015-09, Vol.75, p.158-158

2015

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Influence of collection site on cochlear perilymph sample volume

Journal of pharmacological and toxicological methods, 2013-07, Vol.68 (1), p.e50-e50

2013

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Predictive models of ototoxicity: Evaluation of the suitability of common laboratory species for use on auditory drug safety studies

Journal of pharmacological and toxicological methods, 2014-11, Vol.70 (3), p.311-311

2014

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Application of the distortion product otoacoustic emissions assessment to auditory drug safety evaluations: High throughput auditory screening and impact on drug ototoxicity characterization

Journal of pharmacological and toxicological methods, 2014-11, Vol.70 (3), p.310-311

2014

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Evaluation of a feline model for ototoxicity testing

Journal of pharmacological and toxicological methods, 2014-11, Vol.70 (3), p.348-348

2014

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Age-related hearing loss in the C57BL/6N mouse: Time course analysis of auditory function with implications for auditory safety study design

Journal of pharmacological and toxicological methods, 2013-07, Vol.68 (1), p.e50-e50

2013

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Bilateral cannulation of guinea pigs for ototoxicity studies allows multiple assessments and reduction of animals

Journal of pharmacological and toxicological methods, 2012-09, Vol.66 (2), p.204-204

2012

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A step-wise approach to quantitative arrhythmia assessment: A multi-species and multi-drug validation

Journal of pharmacological and toxicological methods, 2012-09, Vol.66 (2), p.189-189

2012

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Development of a histopathologic evaluation procedure for preliminary ototoxicity screening in guinea pigs

Journal of pharmacological and toxicological methods, 2012-09, Vol.66 (2), p.205-205

2012

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West Yorkshire's Sporting Heroes

Journal of the Society of Archivists, 2012-04, Vol.33 (1), p.75-87

Tapp, Rachel

2012

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Down for the count: The critical endpoint in ototoxicity remains the cytocochleogram

The failure to detect drug-induced sensory loss in standard preclinical studies

Small Compartment Toxicity: CN VIII and Quality of Life: Hearing Loss, Tinnitus, and Balance Disorders

Utility of the auditory brainstem response evaluation in non-clinical drug safety evaluations

Consideration of Potential Systemic Effects of Chronic Administrations in Auditory Studies

An evaluation of staining procedures for cytocochleogram analysis of middle ear organ of corti surface preparations

Distortion Product Otoacoustic Emission Test is Not the Test to Use in Nonclinical Safety Assessment

Ototoxicity: The Radical Drum Beat and Rhythm of Cochlear Hair Cell Life and Death

OTO-104: a sustained-release dexamethasone hydrogel for the treatment of otic disorders

Challenging contemporary status on drug safety evaluation: A case for the implementation of ototoxicity screening in toxicology programs

Identification of NOEL and NOAEL in functional safety (pharmacology) studies: A survey of a contract research organization master schedule

Predicting the Need for a Tier II Ototoxicity Study From Early Renal Function Data

Relative equivalence of CNS safety (FOB) assessment outcomes in male and female Wistar-Han and Sprague-Dawley rats

Auditory brainstem response evaluations in cynomolgus macaques: Considerations for anesthesia and waveform data collection and analysis

Development and evaluation of a Middle Ear PinPort™ for use in otic histology studies

Influence of stimulus parameters and speaker calibration on auditory threshold sensitivity

Influence of collection site on cochlear perilymph sample volume

Predictive models of ototoxicity: Evaluation of the suitability of common laboratory species for use on auditory drug safety studies

Application of the distortion product otoacoustic emissions assessment to auditory drug safety evaluations: High throughput auditory screening and impact on drug ototoxicity characterization

Evaluation of a feline model for ototoxicity testing

Age-related hearing loss in the C57BL/6N mouse: Time course analysis of auditory function with implications for auditory safety study design

Bilateral cannulation of guinea pigs for ototoxicity studies allows multiple assessments and reduction of animals

A step-wise approach to quantitative arrhythmia assessment: A multi-species and multi-drug validation

Development of a histopathologic evaluation procedure for preliminary ototoxicity screening in guinea pigs

West Yorkshire's Sporting Heroes

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