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Pseudomonas aeruginosa Increases Formation of Multidrug-Tolerant Persister Cells in Response to Quorum-Sensing Signaling Molecules

Journal of Bacteriology, 2010-04, Vol.192 (7), p.1946-1955

2010

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Jawsamycin exhibits in vivo antifungal properties by inhibiting Spt14/Gpi3-mediated biosynthesis of glycosylphosphatidylinositol

Nature communications, 2020-07, Vol.11 (1), p.3387-12, Article 3387

2020

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Author Correction: Jawsamycin exhibits in vivo antifungal properties by inhibiting Spt14/Gpi3-mediated biosynthesis of glycosylphosphatidylinositol

Nature communications, 2020-07, Vol.11 (1), p.3913-3913, Article 3913

2020

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Pantethine Rescues Phosphopantothenoylcysteine Synthetase and Phosphopantothenoylcysteine Decarboxylase Deficiency in Escherichia coli but Not in Pseudomonas aeruginosa

Journal of Bacteriology, 2011-07, Vol.193 (13), p.3304-3312

2011

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High-Resolution Genetics Identifies the Lipid Transfer Protein Sec14p as Target for Antifungal Ergolines

PLoS genetics, 2016-11, Vol.12 (11), p.e1006374-e1006374

2016

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The Mevalonate Pathway of Staphylococcus aureus

Journal of Bacteriology, 2009-02, Vol.191 (3), p.851-861

2009

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Identification and Evaluation of Novel Acetolactate Synthase Inhibitors as Antifungal Agents

Antimicrobial Agents and Chemotherapy, 2013-05, Vol.57 (5), p.2272-2280

2013

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Design and structure–activity relationships of potent and selective inhibitors of undecaprenyl pyrophosphate synthase (UPPS): Tetramic, tetronic acids and dihydropyridin-2-ones

Bioorganic & medicinal chemistry, 2008-03, Vol.18 (6), p.1840-1844

2008

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An Integrated Approach for Identification and Target Validation of Antifungal Compounds Active against Erg11p

Antimicrobial Agents and Chemotherapy, 2012-08, Vol.56 (8), p.4233-4240

2012

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Biophysical Investigation of the Mode of Inhibition of Tetramic Acids, the Allosteric Inhibitors of Undecaprenyl Pyrophosphate Synthase

Biochemistry (Easton), 2010-06, Vol.49 (25), p.5366-5376

2010

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Dark chemical matter as a promising starting point for drug lead discovery

Nature chemical biology, 2015-12, Vol.11 (12), p.958

2015

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Discovery of the actinoplanic acid pathway in Streptomyces rapamycinicus reveals a genetically conserved synergism with rapamycin

The Journal of biological chemistry, 2018-12, Vol.293 (52), p.19982-19995

2018

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Drug Target Validation: Lethal Infection Blocked by Inducible Peptide

Proceedings of the National Academy of Sciences - PNAS, 2000-01, Vol.97 (2), p.783-786

2000

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Involvement of Heat Shock Proteins in Candida albicans Biofilm Formation

Journal of molecular microbiology and biotechnology, 2013-10, Vol.23 (6), p.396-400

2013

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Advantages and Challenges of Phenotypic Screens: The Identification of Two Novel Antifungal Geranylgeranyltransferase I Inhibitors

Journal of biomolecular screening, 2016-03, Vol.21 (3), p.306-315

2016

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A Fluorescence-Based High-Throughput Screening Assay to Identify Growth Inhibitors of the Pathogenic Fungus Aspergillus fumigatus

Methods in molecular biology (Clifton, N.J.), 2016-01, Vol.1439, p.171

2016

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Electrostatic Interactions Modulate the RNA-Binding and Transactivation Specificities of the Human Immunodeficiency Virus and Simian Immunodeficiency Virus Tat Proteins

Proceedings of the National Academy of Sciences - PNAS, 1993-02, Vol.90 (4), p.1571-1575

1993

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Structural basis for double-sieve discrimination of L-valine from L-isoleucine and L-threonine by the complex of tRNA(Val) and valyl-tRNA synthetase

Cell, 2000-11, Vol.103 (5), p.793-803

2000

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cwrA, a gene that specifically responds to cell wall damage in Staphylococcus aureus

Microbiology (Society for General Microbiology), 2010-05, Vol.156 (Pt 5), p.1372

2010

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FR171456 is a specific inhibitor of mammalian NSDHL and yeast Erg26p

Nature communications, 2015-10, Vol.6 (1), p.8613-8613, Article 8613

2015

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Aminoacyl tRNA synthetases as targets for new anti‐infectives

The FASEB journal, 1998-12, Vol.12 (15), p.1599-1609

1998

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Structural Basis for Double-Sieve Discrimination of L-Valine from L-Isoleucine and L-Threonine by the Complex of tRNAVal and Valyl-tRNA Synthetase

Cell, 2000-11, Vol.103 (5), p.793-803

2000

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Screening for mevalonate biosynthetic pathway inhibitors using sensitized bacterial strains

Journal of biomolecular screening, 2011-07, Vol.16 (6), p.637-646

2011

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Inhibitors of aminoacyl-tRNA synthetases as novel anti-infectives

Expert opinion on investigational drugs, 2000-08, Vol.9 (8), p.1767-1775

2000

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An expression vector for the phytopathogenic fungus, Ustilago maydis

Gene, 1991-02, Vol.98 (1), p.129-134

1991

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Pseudomonas aeruginosa Increases Formation of Multidrug-Tolerant Persister Cells in Response to Quorum-Sensing Signaling Molecules

Jawsamycin exhibits in vivo antifungal properties by inhibiting Spt14/Gpi3-mediated biosynthesis of glycosylphosphatidylinositol

Author Correction: Jawsamycin exhibits in vivo antifungal properties by inhibiting Spt14/Gpi3-mediated biosynthesis of glycosylphosphatidylinositol

Pantethine Rescues Phosphopantothenoylcysteine Synthetase and Phosphopantothenoylcysteine Decarboxylase Deficiency in Escherichia coli but Not in Pseudomonas aeruginosa

High-Resolution Genetics Identifies the Lipid Transfer Protein Sec14p as Target for Antifungal Ergolines

The Mevalonate Pathway of Staphylococcus aureus

Identification and Evaluation of Novel Acetolactate Synthase Inhibitors as Antifungal Agents

Design and structure–activity relationships of potent and selective inhibitors of undecaprenyl pyrophosphate synthase (UPPS): Tetramic, tetronic acids and dihydropyridin-2-ones

An Integrated Approach for Identification and Target Validation of Antifungal Compounds Active against Erg11p

Biophysical Investigation of the Mode of Inhibition of Tetramic Acids, the Allosteric Inhibitors of Undecaprenyl Pyrophosphate Synthase

Dark chemical matter as a promising starting point for drug lead discovery

Discovery of the actinoplanic acid pathway in Streptomyces rapamycinicus reveals a genetically conserved synergism with rapamycin

Drug Target Validation: Lethal Infection Blocked by Inducible Peptide

Involvement of Heat Shock Proteins in Candida albicans Biofilm Formation

Advantages and Challenges of Phenotypic Screens: The Identification of Two Novel Antifungal Geranylgeranyltransferase I Inhibitors

A Fluorescence-Based High-Throughput Screening Assay to Identify Growth Inhibitors of the Pathogenic Fungus Aspergillus fumigatus

Electrostatic Interactions Modulate the RNA-Binding and Transactivation Specificities of the Human Immunodeficiency Virus and Simian Immunodeficiency Virus Tat Proteins

Structural basis for double-sieve discrimination of L-valine from L-isoleucine and L-threonine by the complex of tRNA(Val) and valyl-tRNA synthetase

cwrA, a gene that specifically responds to cell wall damage in Staphylococcus aureus

FR171456 is a specific inhibitor of mammalian NSDHL and yeast Erg26p

Aminoacyl tRNA synthetases as targets for new anti‐infectives

Structural Basis for Double-Sieve Discrimination of L-Valine from L-Isoleucine and L-Threonine by the Complex of tRNAVal and Valyl-tRNA Synthetase

Screening for mevalonate biosynthetic pathway inhibitors using sensitized bacterial strains

Inhibitors of aminoacyl-tRNA synthetases as novel anti-infectives

An expression vector for the phytopathogenic fungus, Ustilago maydis

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