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Peptide Agonist of the Thrombopoietin Receptor as Potent as the Natural Cytokine

Science (American Association for the Advancement of Science), 1997-06, Vol.276 (5319), p.1696-1699

1997

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X-ray Crystal Structures of Candida albicans Dihydrofolate Reductase: High Resolution Ternary Complexes in Which the Dihydronicotinamide Moiety of NADPH Is Displaced by an Inhibitor

Journal of medicinal chemistry, 2001-08, Vol.44 (18), p.2928-2932

2001

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α-Fluoro-β-alanine: Effects on the antitumor activity and toxicity of 5-fluorouracil

Biochemical pharmacology, 2000-04, Vol.59 (8), p.953-960

2000

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Characterization of Candida albicans Dihydrofolate Reductase

The Journal of biological chemistry, 1989-01, Vol.264 (2), p.1100-1107

1989

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High-Affinity Inhibitors of Dihydrofolate Reductase: Antimicrobial and Anticancer Activities of 7,8-Dialkyl-1,3-diaminopyrrolo[3,2-f]quinazolines with Small Molecular Size

Journal of medicinal chemistry, 1996-02, Vol.39 (4), p.892-903

1996

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Selective Inhibitors of Candida albicans Dihydrofolate Reductase: Activity and Selectivity of 5-(Arylthio)-2,4-diaminoquinazolines

Journal of medicinal chemistry, 1995-09, Vol.38 (18), p.3608-3616

1995

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X-ray crystallographic studies of Candida albicans dihydrofolate reductase. High resolution structures of the holoenzyme and an inhibited ternary complex

The Journal of biological chemistry, 1997-11, Vol.272 (48), p.30289-30298

1997

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Refolding of Recombinant Pneumocystis carinii Dihydrofolate Reductase and Characterization of the Enzyme

Protein expression and purification, 1993-02, Vol.4 (1), p.16-23

1993

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Characterization and amino acid sequence of Neisseria gonorrhoeae dihydrofolate reductase

The Journal of biological chemistry, 1984-10, Vol.259 (19), p.12291-12298

1984

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Species-specific irreversible inhibition of Neisseria gonorrhoeae dihydrofolate reductase by a substituted 2,4-diamino-5-benzylpyrimidine

The Journal of biological chemistry, 1984-10, Vol.259 (19), p.12299-12305

1984

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Synthesis of 1,3-diamino-7,8,9,10-tetrahydropyrido[3,2-f]-quinazolines. Inhibitors of Candida albicans dihydrofolate reductase as potential antifungal agents

Journal of heterocyclic chemistry, 1997-01, Vol.34 (1), p.145-151

1997

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Preclinical development of eniluracil: enhancing the therapeutic index and dosing convenience of 5-fluorouracil

Investigational new drugs, 2000-11, Vol.18 (4), p.365-371

2000

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Kinetics of methotrexate binding to dihydrofolate reductase from Neisseria gonorrhoeae

Biochemical pharmacology, 1984-07, Vol.33 (13), p.2101-2107

1984

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Substrate-inhibitor cooperative interactions with microbial dihydrofolate reductases

Advances in enzyme regulation, 1987, Vol.26, p.3-15

1987

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Effects of delta 9-tetrahydrocannabinol and cannabidiol on phospholipase and other enzymes regulating arachidonate metabolism

Prostaglandins and medicine, 1980-06, Vol.4 (6), p.409-417

1980

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High-affinity inhibitors of dihydrofolate reductase : antimicrobial and anticancer activities of 7,8-dialkyl-1,3-diaminopyrrolo[3,2-f]quinazolines with small molecular size

Journal of medicinal chemistry, 1995, Vol.39 (4), p.892-903

1995

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Inhibitors of dihydrofolate reductase: Design, synthesis and antimicrobial activities of 2,4-diamino-6-methyl-5-ethynylpyrimidines

Journal of heterocyclic chemistry, 1999-01, Vol.36 (1), p.145-148

1999

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Structures of Candida albicans dihydrofolate reductase: holoenzyme and ternary inhibitor complexes

Acta crystallographica. Section A, Foundations of crystallography, 1996-08, Vol.52 (a1), p.C208-C209

1996

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Synthesis of 5-(4-substituted benzyl)-2,4-diaminoquinazolines as inhibitors of candida albicans dihydrofolate reductase

Journal of heterocyclic chemistry, 1995-09, Vol.32 (5), p.1461-1465

1995

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ChemInform Abstract: Synthesis of 5-(4-Substituted benzyl)-2,4-diaminoquinazolines as Inhibitors of Candida albicans Dihydrofolate Reductase

ChemInform, 1996-03, Vol.27 (13), p.no-no

1996

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Synthesis of prostaglandin 6-keto F 1α by cultured aortic smooth muscle cells and stimulation of its formation in a coupled system with platelet lysates

Prostaglandins, 1978, Vol.15 (3), p.399-408

1978

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Prostaglandin synthesis in homogenates of cultured neuroblastoma cells

Prostaglandins and medicine, 1979-03, Vol.2 (3), p.225-234

1979

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ChemInform Abstract: Synthesis of 1,3-Diamino-7,8,9,10-tetrahydropyrido(3,2-f)quinazolines. Inhibitors of Candida albicans Dihydrofolate Reductase as Potential Antifungal Agents

ChemInform, 1997-07, Vol.28 (28), p.no-no

1997

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Synthesis of prostaglandin 6-keto F1alpha by cultured aortic smooth muscle cells and stimulation of its formation in a coupled system with platelet lysates

Prostaglandins, 1978-03, Vol.15 (3), p.399-408

1978

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ChemInform Abstract: Selective Inhibitors of Candida albicans Dihydrofolate Reductase: Activity and Selectivity of 5-(Arylthio)-2,4-diaminoquinazolines

ChemInform, 1995-12, Vol.26 (52), p.no-no

1995

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Peptide Agonist of the Thrombopoietin Receptor as Potent as the Natural Cytokine

X-ray Crystal Structures of Candida albicans Dihydrofolate Reductase: High Resolution Ternary Complexes in Which the Dihydronicotinamide Moiety of NADPH Is Displaced by an Inhibitor

α-Fluoro-β-alanine: Effects on the antitumor activity and toxicity of 5-fluorouracil

Characterization of Candida albicans Dihydrofolate Reductase

High-Affinity Inhibitors of Dihydrofolate Reductase: Antimicrobial and Anticancer Activities of 7,8-Dialkyl-1,3-diaminopyrrolo[3,2-f]quinazolines with Small Molecular Size

Selective Inhibitors of Candida albicans Dihydrofolate Reductase: Activity and Selectivity of 5-(Arylthio)-2,4-diaminoquinazolines

X-ray crystallographic studies of Candida albicans dihydrofolate reductase. High resolution structures of the holoenzyme and an inhibited ternary complex

Refolding of Recombinant Pneumocystis carinii Dihydrofolate Reductase and Characterization of the Enzyme

Characterization and amino acid sequence of Neisseria gonorrhoeae dihydrofolate reductase

Species-specific irreversible inhibition of Neisseria gonorrhoeae dihydrofolate reductase by a substituted 2,4-diamino-5-benzylpyrimidine

Synthesis of 1,3-diamino-7,8,9,10-tetrahydropyrido[3,2-f]-quinazolines. Inhibitors of Candida albicans dihydrofolate reductase as potential antifungal agents

Preclinical development of eniluracil: enhancing the therapeutic index and dosing convenience of 5-fluorouracil

Kinetics of methotrexate binding to dihydrofolate reductase from Neisseria gonorrhoeae

Substrate-inhibitor cooperative interactions with microbial dihydrofolate reductases

Effects of delta 9-tetrahydrocannabinol and cannabidiol on phospholipase and other enzymes regulating arachidonate metabolism

High-affinity inhibitors of dihydrofolate reductase : antimicrobial and anticancer activities of 7,8-dialkyl-1,3-diaminopyrrolo[3,2-f]quinazolines with small molecular size

Inhibitors of dihydrofolate reductase: Design, synthesis and antimicrobial activities of 2,4-diamino-6-methyl-5-ethynylpyrimidines

Structures of Candida albicans dihydrofolate reductase: holoenzyme and ternary inhibitor complexes

Synthesis of 5-(4-substituted benzyl)-2,4-diaminoquinazolines as inhibitors of candida albicans dihydrofolate reductase

ChemInform Abstract: Synthesis of 5-(4-Substituted benzyl)-2,4-diaminoquinazolines as Inhibitors of Candida albicans Dihydrofolate Reductase

Synthesis of prostaglandin 6-keto F 1α by cultured aortic smooth muscle cells and stimulation of its formation in a coupled system with platelet lysates

Prostaglandin synthesis in homogenates of cultured neuroblastoma cells

ChemInform Abstract: Synthesis of 1,3-Diamino-7,8,9,10-tetrahydropyrido(3,2-f)quinazolines. Inhibitors of Candida albicans Dihydrofolate Reductase as Potential Antifungal Agents

Synthesis of prostaglandin 6-keto F1alpha by cultured aortic smooth muscle cells and stimulation of its formation in a coupled system with platelet lysates

ChemInform Abstract: Selective Inhibitors of Candida albicans Dihydrofolate Reductase: Activity and Selectivity of 5-(Arylthio)-2,4-diaminoquinazolines

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