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The Target of Ezetimibe Is Niemann-Pick C1-Like 1 (NPC1L1)

Proceedings of the National Academy of Sciences - PNAS, 2005-06, Vol.102 (23), p.8132-8137

2005

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Pharmacological properties of MK-3207, a potent and orally active calcitonin gene-related peptide receptor antagonist

The Journal of pharmacology and experimental therapeutics, 2010-04, Vol.333 (1), p.152-160

2010

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Characterization of a New Class of Potent Inhibitors of the Voltage-Gated Sodium Channel Nav1.7

Biochemistry (Easton), 2007-12, Vol.46 (50), p.14693-14703

2007

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Evidence for the bioactivation of zomepirac and tolmetin by an oxidative pathway: identification of glutathione adducts in vitro in human liver microsomes and in vivo in rats

Drug metabolism and disposition, 2006-01, Vol.34 (1), p.145-151

2006

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Disposition of Caspofungin, a Novel Antifungal Agent, in Mice, Rats, Rabbits, and Monkeys

Antimicrobial Agents and Chemotherapy, 2004-04, Vol.48 (4), p.1272-1280

2004

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Examining the binding properties of MK-0974: A CGRP receptor antagonist for the acute treatment of migraine

European journal of pharmacology, 2009-01, Vol.602 (2), p.250-254

2009

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Design and Synthesis of Highly Potent Benzodiazepine γ-Secretase Inhibitors: Preparation of (2S,3R)-3-(3,4- Difluorophenyl)-2-(4-fluorophenyl)-4- hydroxy-N-((3S)-1-methyl-2-oxo-5- phenyl-2,3-dihydro-1H-benzo[e][1,4]- diazepin-3-yl)butyramide by Use of an Asymmetric Ireland−Claisen Rearrangement

Journal of medicinal chemistry, 2003-06, Vol.46 (12), p.2275-2278

2003

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Addressing the metabolic activation potential of new leads in drug discovery: a case study using ion trap mass spectrometry and tritium labeling techniques

Journal of mass spectrometry., 2003-02, Vol.38 (2), p.211-221

2003

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Metabolic Activation of a 1,3-Disubstituted Piperazine Derivative: Evidence for a Novel Ring Contraction to an Imidazoline

Chemical research in toxicology, 2005-02, Vol.18 (2), p.271-276

2005

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The pKa and keto-enol equilibrium constant of acetone in aqueous solution

Journal of the American Chemical Society, 1984-01, Vol.106 (2), p.460-462

1984

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A Disubstituted Succinamide Is a Potent Sodium Channel Blocker with Efficacy in a Rat Pain Model

Biochemistry (Easton), 2004-08, Vol.43 (30), p.9866-9876

2004

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Di-Substituted Cyclohexyl Derivatives Bind to Two Identical Sites with Positive Cooperativity on the Voltage-Gated Potassium Channel, Kv1.3

Biochemistry (Easton), 2003-04, Vol.42 (16), p.4733-4743

2003

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3-Pyridyloxypropanolamine agonists of the β3 adrenergic receptor with improved pharmacokinetic properties

Bioorganic & medicinal chemistry letters, 1998-08, Vol.8 (16), p.2111-2116

1998

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Molecular and Cellular Pharmacology: Examining the binding properties of MK-0974: A CGRP receptor antagonist for the acute treatment of migraine

European journal of pharmacology, 2009-01, Vol.602 (2-3), p.250-254

2009

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Characterization of a New Class of Potent Inhibitors of the Voltage-Gated Sodium Channel Nav1.7

Biochemistry (Easton), 2007-12, Vol.46 (50), p.14693-14703

2007

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Di-substituted cyclohexyl derivatives bind to two identical sites with positive cooperativity on the voltage-gated potassium channel, K(v)1.3

Biochemistry (Easton), 2003-04, Vol.42 (16), p.4733-4743

2003

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Tritium isotope effects on carbon-13 NMR chemical shifts

Journal of the American Chemical Society, 1986-03, Vol.108 (6), p.1356-1357

1986

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Di-Substituted Cyclohexyl Derivatives Bind to Two Identical Sites with Positive Cooperativity on the Voltage-Gated Potassium Channel, K v 1.3

Biochemistry (Easton), 2003-04, Vol.42 (16), p.4733-4743

2003

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Design and Synthesis of Highly Potent Benzodiazepine γ-Secretase Inhibitors: Preparation of (2 S ,3 R )-3-(3,4- Difluorophenyl)-2-(4-fluorophenyl)-4- hydroxy- N -((3 S )-1-methyl-2-oxo-5- phenyl-2,3-dihydro-1 H -benzo[ e ][1,4]- diazepin-3-yl)butyramide by Use of an Asymmetric Ireland−Claisen Rearrangement

Journal of medicinal chemistry, 2003-06, Vol.46 (12), p.2275-2278

2003

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Design and synthesis of highly potent benzodiazepine γ-secretase inhibitors: Preparation of (2S, 3R)-3-(3,4-difluorophenyl)-2-(4-fluorophenyl)-4-hydroxy-N-((3S)-1-methyl-2-o xo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]-diazepin-3-yl)butyramide by use of an asymmetric Ireland-Claisen rearrangement

Journal of medicinal chemistry, 2003, Vol.46 (12), p.2275-2278

2003

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N-succinimidyl propionate: Characterisation and optimum conditions for use as a tritium labelling reagent for proteins

Journal of labelled compounds & radiopharmaceuticals, 1983-02, Vol.20 (2), p.277-284

1983

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Synthesis of carbon-14 and tritium analogues of the phospholipid antitumor agent SDZ 62-834 zi

Journal of labelled compounds & radiopharmaceuticals, 1992-10, Vol.31 (10), p.829-835

1992

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Simple modification of a gas chromatography for radio-assay of tritiumlabelled compounds

Journal of Chromatography A, 1984, Vol.287, p.381-384

1984

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Comparative analysis of Student's live online learning readiness during the coronavirus (COVID-19) pandemic in the higher education sector

Computers and education, 2021-07, Vol.168, p.104211-104211, Article 104211

2021

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The Target of Ezetimibe Is Niemann-Pick C1-Like 1 (NPC1L1)

Pharmacological properties of MK-3207, a potent and orally active calcitonin gene-related peptide receptor antagonist

Characterization of a New Class of Potent Inhibitors of the Voltage-Gated Sodium Channel Nav1.7

Evidence for the bioactivation of zomepirac and tolmetin by an oxidative pathway: identification of glutathione adducts in vitro in human liver microsomes and in vivo in rats

Disposition of Caspofungin, a Novel Antifungal Agent, in Mice, Rats, Rabbits, and Monkeys

Examining the binding properties of MK-0974: A CGRP receptor antagonist for the acute treatment of migraine

Design and Synthesis of Highly Potent Benzodiazepine γ-Secretase Inhibitors: Preparation of (2S,3R)-3-(3,4- Difluorophenyl)-2-(4-fluorophenyl)-4- hydroxy-N-((3S)-1-methyl-2-oxo-5- phenyl-2,3-dihydro-1H-benzo[e][1,4]- diazepin-3-yl)butyramide by Use of an Asymmetric Ireland−Claisen Rearrangement

Addressing the metabolic activation potential of new leads in drug discovery: a case study using ion trap mass spectrometry and tritium labeling techniques

Metabolic Activation of a 1,3-Disubstituted Piperazine Derivative: Evidence for a Novel Ring Contraction to an Imidazoline

The pKa and keto-enol equilibrium constant of acetone in aqueous solution

A Disubstituted Succinamide Is a Potent Sodium Channel Blocker with Efficacy in a Rat Pain Model

Di-Substituted Cyclohexyl Derivatives Bind to Two Identical Sites with Positive Cooperativity on the Voltage-Gated Potassium Channel, Kv1.3

Platensimycin is a selective FabF inhibitor with potent antibiotic properties

3-Pyridyloxypropanolamine agonists of the β3 adrenergic receptor with improved pharmacokinetic properties

Molecular and Cellular Pharmacology: Examining the binding properties of MK-0974: A CGRP receptor antagonist for the acute treatment of migraine

Characterization of a New Class of Potent Inhibitors of the Voltage-Gated Sodium Channel Nav1.7

Di-substituted cyclohexyl derivatives bind to two identical sites with positive cooperativity on the voltage-gated potassium channel, K(v)1.3

Tritium isotope effects on carbon-13 NMR chemical shifts

Di-Substituted Cyclohexyl Derivatives Bind to Two Identical Sites with Positive Cooperativity on the Voltage-Gated Potassium Channel, K v 1.3

Design and synthesis of highly potent benzodiazepine γ-secretase inhibitors: Preparation of (2S, 3R)-3-(3,4-difluorophenyl)-2-(4-fluorophenyl)-4-hydroxy-N-((3S)-1-methyl-2-o xo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]-diazepin-3-yl)butyramide by use of an asymmetric Ireland-Claisen rearrangement

N-succinimidyl propionate: Characterisation and optimum conditions for use as a tritium labelling reagent for proteins

Synthesis of carbon-14 and tritium analogues of the phospholipid antitumor agent SDZ 62-834 zi

Simple modification of a gas chromatography for radio-assay of tritiumlabelled compounds

Comparative analysis of Student's live online learning readiness during the coronavirus (COVID-19) pandemic in the higher education sector

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