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Nucleic acid-based drug delivery strategies

Journal of controlled release, 2020-07, Vol.323, p.240-252

2020

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Blurring the Role of Oligonucleotides: Spherical Nucleic Acids as a Drug Delivery Vehicle

Journal of the American Chemical Society, 2016-08, Vol.138 (34), p.10834-10837

2016

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Molecular spherical nucleic acids

Proceedings of the National Academy of Sciences - PNAS, 2018-04, Vol.115 (17), p.4340-4344

2018

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Depth-Profiling the Nuclease Stability and the Gene Silencing Efficacy of Brush-Architectured Poly(ethylene glycol)–DNA Conjugates

Journal of the American Chemical Society, 2017-08, Vol.139 (31), p.10605-10608

2017

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Effect of PEG Architecture on the Hybridization Thermodynamics and Protein Accessibility of PEGylated Oligonucleotides

Angewandte Chemie (International ed.), 2017-01, Vol.56 (5), p.1239-1243

International ed. in English, 2017

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Rapid de novo discovery of peptidomimetic affinity reagents for human angiotensin converting enzyme 2

Communications chemistry, 2022-01, Vol.5 (1), p.8-10, Article 8

2022

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Photolabile Self-Immolative DNA-Drug Nanostructures

Methods in molecular biology (Clifton, N.J.), 2017, Vol.1570, p.209

2017

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Polycondensation of Polymer Brushes via DNA Hybridization

Journal of the American Chemical Society, 2014-07, Vol.136 (29), p.10214-10217

2014

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Light-Triggered, Self-Immolative Nucleic Acid-Drug Nanostructures

Journal of the American Chemical Society, 2015-05, Vol.137 (19), p.6112-6115

2015

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Effective Antisense Gene Regulation via Noncationic, Polyethylene Glycol Brushes

Journal of the American Chemical Society, 2016-07, Vol.138 (29), p.9097-9100

2016

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Facile synthesis of nucleic acid-polymer amphiphiles and their self-assembly

Chemical communications (Cambridge, England), 2015-05, Vol.51 (37), p.7843-7846

2015

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Self-immolative polymers in biomedicine

Journal of materials chemistry. B, Materials for biology and medicine, 2020-08, Vol.8 (31), p.6697-679

2020

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Exploring the Structural Diversity of DNA Bottlebrush Polymers Using an Oligonucleotide Macromonomer Approach

Macromolecules, 2022-03, Vol.55 (6), p.2235-2242

2022

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Modulating the Cellular Immune Response of Oligonucleotides by Brush Polymer‐Assisted Compaction

Small (Weinheim an der Bergstrasse, Germany), 2017-11, Vol.13 (43), p.n/a

2017

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Providing Oligonucleotides with Steric Selectivity by Brush-Polymer-Assisted Compaction

Journal of the American Chemical Society, 2015-10, Vol.137 (39), p.12466-12469

2015

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Modulating the Depolymerization of Self-Immolative Brush Polymers with Poly(benzyl ether) Backbones

Macromolecules, 2018-04, Vol.51 (8), p.2899-2905

2018

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Improving the Enzymatic Stability and the Pharmacokinetics of Oligonucleotides via DNA-Backboned Bottlebrush Polymers

Nano letters, 2018-11, Vol.18 (11), p.7378-7382

2018

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Precision Tuning of DNA- and Poly(ethylene glycol)-Based Nanoparticles via Coassembly for Effective Antisense Gene Regulation

Chemistry of materials, 2017-12, Vol.29 (23), p.9882-9886

2017

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Spherical Nucleic Acids for Topical Treatment of Hyperpigmentation

Journal of the American Chemical Society, 2021-01, Vol.143 (3), p.1296-1300

2021

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Self-Assembled DNA–PEG Bottlebrushes Enhance Antisense Activity and Pharmacokinetics of Oligonucleotides

ACS applied materials & interfaces, 2020-10, Vol.12 (41), p.45830-45837

2020

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Bottlebrush Polymer-Conjugated Melittin Exhibits Enhanced Antitumor Activity and Better Safety Profile

ACS applied materials & interfaces, 2021-09, Vol.13 (36), p.42533-42542

2021

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Bottlebrush Polymer-Conjugated Melittin Exhibits Enhanced Anti-Tumor Activity and Better Safety Profile

ACS applied materials & interfaces, 2021-09, Vol.13 (36), p.42533-42542

2021

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Expanding the Materials Space of DNA via Organic-Phase Ring-Opening Metathesis Polymerization

Chem, 2019-06, Vol.5 (6), p.1584-1596

2019

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Facile synthesis of nucleic acid-polymer amphiphiles and their self-assemblyElectronic supplementary information (ESI) available: Experimental details and additional figures. See DOI: 10.1039/c5cc01934f

2015-04

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Bottlebrush-architectured poly(ethylene glycol) as an efficient vector for RNA interference in vivo

Science advances, 2019-02, Vol.5 (2), p.eaav9322

2019

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Nucleic acid-based drug delivery strategies

Blurring the Role of Oligonucleotides: Spherical Nucleic Acids as a Drug Delivery Vehicle

Molecular spherical nucleic acids

Depth-Profiling the Nuclease Stability and the Gene Silencing Efficacy of Brush-Architectured Poly(ethylene glycol)–DNA Conjugates

Effect of PEG Architecture on the Hybridization Thermodynamics and Protein Accessibility of PEGylated Oligonucleotides

Rapid de novo discovery of peptidomimetic affinity reagents for human angiotensin converting enzyme 2

Photolabile Self-Immolative DNA-Drug Nanostructures

Polycondensation of Polymer Brushes via DNA Hybridization

Light-Triggered, Self-Immolative Nucleic Acid-Drug Nanostructures

Effective Antisense Gene Regulation via Noncationic, Polyethylene Glycol Brushes

Facile synthesis of nucleic acid-polymer amphiphiles and their self-assembly

Self-immolative polymers in biomedicine

Exploring the Structural Diversity of DNA Bottlebrush Polymers Using an Oligonucleotide Macromonomer Approach

Modulating the Cellular Immune Response of Oligonucleotides by Brush Polymer‐Assisted Compaction

Providing Oligonucleotides with Steric Selectivity by Brush-Polymer-Assisted Compaction

Modulating the Depolymerization of Self-Immolative Brush Polymers with Poly(benzyl ether) Backbones

Improving the Enzymatic Stability and the Pharmacokinetics of Oligonucleotides via DNA-Backboned Bottlebrush Polymers

Precision Tuning of DNA- and Poly(ethylene glycol)-Based Nanoparticles via Coassembly for Effective Antisense Gene Regulation

Spherical Nucleic Acids for Topical Treatment of Hyperpigmentation

Self-Assembled DNA–PEG Bottlebrushes Enhance Antisense Activity and Pharmacokinetics of Oligonucleotides

Bottlebrush Polymer-Conjugated Melittin Exhibits Enhanced Antitumor Activity and Better Safety Profile

Bottlebrush Polymer-Conjugated Melittin Exhibits Enhanced Anti-Tumor Activity and Better Safety Profile

Expanding the Materials Space of DNA via Organic-Phase Ring-Opening Metathesis Polymerization

Facile synthesis of nucleic acid-polymer amphiphiles and their self-assemblyElectronic supplementary information (ESI) available: Experimental details and additional figures. See DOI: 10.1039/c5cc01934f

Bottlebrush-architectured poly(ethylene glycol) as an efficient vector for RNA interference in vivo

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