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Invalidation of dieckol and 1,2,3,4,6-pentagalloylglucose (PGG) as SARS-CoV-2 main protease inhibitors and the discovery of PGG as a papain-like protease inhibitor

Medicinal chemistry research, 2022, Vol.31 (7), p.1147-1153

2022

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Validation and invalidation of SARS-CoV-2 main protease inhibitors using the Flip-GFP and Protease-Glo luciferase assays

Acta pharmaceutica Sinica. B, 2022-04, Vol.12 (4), p.1636-1651

2022

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Naturally Occurring Mutations of SARS-CoV-2 Main Protease Confer Drug Resistance to Nirmatrelvir

ACS central science, 2023-08, Vol.9 (8), p.1658-1669

2023

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A yeast-based system to study SARS-CoV-2 Mpro structure and to identify nirmatrelvir resistant mutations

PLoS pathogens, 2023-08, Vol.19 (8), p.e1011592

2023

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Progress and Challenges in Targeting the SARS-CoV‑2 Papain-like Protease

Journal of medicinal chemistry, 2022-06, Vol.65 (11), p.7561-7580

2022

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SARS-CoV‑2 Main Protease Drug Design, Assay Development, and Drug Resistance Studies

Accounts of chemical research, 2023-01, Vol.56 (2), p.157-168

2023

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Rational design of a deuterium-containing M2-S31N channel blocker UAWJ280 with in vivo antiviral efficacy against both oseltamivir sensitive and -resistant influenza A viruses

Emerging microbes & infections, 2021-01, Vol.10 (1), p.1832-1848

2021

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An Overview of Antivirals against Monkeypox Virus and Other Orthopoxviruses

Journal of medicinal chemistry, 2023-04, Vol.66 (7), p.4468-4490

2023

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Exploring diverse reactive warheads for the design of SARS-CoV-2 main protease inhibitors

European journal of medicinal chemistry, 2023-11, Vol.259 (C), p.115667-115667, Article 115667

2023

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Discovery of Di- and Trihaloacetamides as Covalent SARS-CoV‑2 Main Protease Inhibitors with High Target Specificity

Journal of the American Chemical Society, 2021-12, Vol.143 (49), p.20697-20709

2021

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Structure and dynamics of the proton-selective histidine and the gating tryptophan in an inward rectifying hybrid influenza B and A virus M2 proton channel

Physical chemistry chemical physics : PCCP, 2024-07, Vol.26 (30), p.20629-20644

2024

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FlipGFP protease assay for evaluating in vitro inhibitory activity against SARS-CoV-2 Mpro and PLpro

STAR protocols, 2023-06, Vol.4 (2), p.102323-102323, Article 102323

2023

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FlipGFP protease assay for evaluating in vitro inhibitory activity against SARS-CoV-2 M pro and PL pro

STAR protocols, 2023-05, Vol.4 (2), p.102323

2023

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Design of a SARS-CoV-2 papain-like protease inhibitor with antiviral efficacy in a mouse model

Science (American Association for the Advancement of Science), 2024-03, Vol.383 (6690), p.1434-1440

2024

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CypA/TAF15/STAT5A/miR-514a-3p feedback loop drives ovarian cancer metastasis

Oncogene, 2024-10

2024

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Structure-based design of SARS-CoV-2 papain-like protease inhibitors

European journal of medicinal chemistry, 2024-01, Vol.264 (C), p.116011, Article 116011

2024

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Telaprevir Treatment Reduces Paralysis in a Mouse Model of Enterovirus D68 Acute Flaccid Myelitis

Journal of virology, 2023-05, Vol.97 (5), p.e0015623

2023

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Structure-Based Lead Optimization of Enterovirus D68 2A Protease Inhibitors

Journal of medicinal chemistry, 2023-11, Vol.66 (21), p.14544-14563

2023

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Structure-based design of SARS-CoV-2 papain-like protease inhibitors

European journal of medicinal chemistry, 2023-12, Vol.264

2023

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A yeast-based system to study SARS-CoV-2 M.sup.pro structure and to identify nirmatrelvir resistant mutations

PLoS pathogens, 2023-08, Vol.19 (8), p.e1011592

2023

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Molecular Mechanism of the Potent Benzopyran-G1 Blocker of Heteromeric G-Protein Gated Potassium Channels

Biophysical journal, 2021-02, Vol.120 (3), p.203a-203a

2021

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A benzopyran with antiarrhythmic activity is an inhibitor of Kir3.1-containing potassium channels

The Journal of biological chemistry, 2021-01, Vol.296, p.100535-100535, Article 100535

2021

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Quality analysis combined with mass spectrometry imaging reveal the difference between wild and cultivated Phyllanthus emblica Linn.: From chemical composition to molecular mechanism

Arabian journal of chemistry, 2022-06, Vol.15 (6), p.103790, Article 103790

2022

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Hepatoprotective Effects of Different Extracts From Triphala Against CCl4-Induced Acute Liver Injury in Mice

Frontiers in pharmacology, 2021-07, Vol.12, p.664607-664607

2021

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The impact of thermal extraction on the quality of Phyllanthus emblica Linn. fruit: A systematic study based on compositional changes

Arabian journal of chemistry, 2023-04, Vol.16 (4), p.104562, Article 104562

2023

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Invalidation of dieckol and 1,2,3,4,6-pentagalloylglucose (PGG) as SARS-CoV-2 main protease inhibitors and the discovery of PGG as a papain-like protease inhibitor

Validation and invalidation of SARS-CoV-2 main protease inhibitors using the Flip-GFP and Protease-Glo luciferase assays

Naturally Occurring Mutations of SARS-CoV-2 Main Protease Confer Drug Resistance to Nirmatrelvir

A yeast-based system to study SARS-CoV-2 Mpro structure and to identify nirmatrelvir resistant mutations

Progress and Challenges in Targeting the SARS-CoV‑2 Papain-like Protease

SARS-CoV‑2 Main Protease Drug Design, Assay Development, and Drug Resistance Studies

Rational design of a deuterium-containing M2-S31N channel blocker UAWJ280 with in vivo antiviral efficacy against both oseltamivir sensitive and -resistant influenza A viruses

An Overview of Antivirals against Monkeypox Virus and Other Orthopoxviruses

Exploring diverse reactive warheads for the design of SARS-CoV-2 main protease inhibitors

Discovery of Di- and Trihaloacetamides as Covalent SARS-CoV‑2 Main Protease Inhibitors with High Target Specificity

Structure and dynamics of the proton-selective histidine and the gating tryptophan in an inward rectifying hybrid influenza B and A virus M2 proton channel

FlipGFP protease assay for evaluating in vitro inhibitory activity against SARS-CoV-2 Mpro and PLpro

FlipGFP protease assay for evaluating in vitro inhibitory activity against SARS-CoV-2 M pro and PL pro

Design of a SARS-CoV-2 papain-like protease inhibitor with antiviral efficacy in a mouse model

CypA/TAF15/STAT5A/miR-514a-3p feedback loop drives ovarian cancer metastasis

Structure-based design of SARS-CoV-2 papain-like protease inhibitors

Telaprevir Treatment Reduces Paralysis in a Mouse Model of Enterovirus D68 Acute Flaccid Myelitis

Structure-Based Lead Optimization of Enterovirus D68 2A Protease Inhibitors

Structure-based design of SARS-CoV-2 papain-like protease inhibitors

A yeast-based system to study SARS-CoV-2 M.sup.pro structure and to identify nirmatrelvir resistant mutations

Molecular Mechanism of the Potent Benzopyran-G1 Blocker of Heteromeric G-Protein Gated Potassium Channels

A benzopyran with antiarrhythmic activity is an inhibitor of Kir3.1-containing potassium channels

Quality analysis combined with mass spectrometry imaging reveal the difference between wild and cultivated Phyllanthus emblica Linn.: From chemical composition to molecular mechanism

Hepatoprotective Effects of Different Extracts From Triphala Against CCl4-Induced Acute Liver Injury in Mice

The impact of thermal extraction on the quality of Phyllanthus emblica Linn. fruit: A systematic study based on compositional changes

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