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Application of Human Induced Pluripotent Stem Cell-Derived Intestinal Organoids as a Model of Epithelial Damage and Fibrosis in Inflammatory Bowel Disease

Biological and Pharmaceutical Bulletin, 2020/07/01, Vol.43(7), pp.1088-1095

2020

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Accumulation of Toxic Advanced Glycation End-Products Induces Cytotoxicity and Inflammation in Hepatocyte-Like Cells Differentiated from Human Induced Pluripotent Stem Cells

Biological and Pharmaceutical Bulletin, 2021/10/01, Vol.44(10), pp.1399-1402

2021

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Culture methods focusing on bile canalicular formation using primary human hepatocytes in a short time

In vitro cellular & developmental biology. Animal, 2023-09, Vol.59 (8), p.606-614

2023

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Generation of Intestinal Organoids Suitable for Pharmacokinetic Studies from Human Induced Pluripotent Stem Cells

Drug metabolism and disposition, 2018-11, Vol.46 (11), p.1572-1580

2018

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Pharmacokinetic functions of human induced pluripotent stem cell-derived small intestinal epithelial cells

Drug metabolism and pharmacokinetics, 2020-08, Vol.35 (4), p.374-382

2020

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Effect of Topiroxostat on Reducing Oxidative Stress in the Aorta of Streptozotocin-Induced Diabetic Rats

Biological and Pharmaceutical Bulletin, 2023/02/01, Vol.46(2), pp.272-278

2023

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Effect of Anagliptin on Vascular Injury in the Femoral Artery of Type 2 Diabetic Rats

Biological and Pharmaceutical Bulletin, 2024/01/19, Vol.47(1), pp.204-212

2024

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Application of a Human Intestinal Epithelial Cell Monolayer to the Prediction of Oral Drug Absorption in Humans as a Superior Alternative to the Caco-2 Cell Monolayer

Journal of pharmaceutical sciences, 2016-02, Vol.105 (2), p.915-924

2016

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New Maintenance Culture Method for Intestinal Stem Cells Derived from Human Induced Pluripotent Stem Cells

Biological and Pharmaceutical Bulletin, 2024/01/01, Vol.47(1), pp.120-129

2024

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Laminin 221 fragment is suitable for the differentiation of human induced pluripotent stem cells into brain microvascular endothelial-like cells with robust barrier integrity

Fluids and barriers of the CNS, 2020-03, Vol.17 (1), p.25-25, Article 25

2020

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Functional analysis of carboxylesterase in human induced pluripotent stem cell-derived enterocytes

Biochemical and biophysical research communications, 2017-04, Vol.486 (1), p.143-148

2017

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Inhibition of transforming growth factor beta signaling pathway promotes differentiation of human induced pluripotent stem cell-derived brain microvascular endothelial-like cells

Fluids and barriers of the CNS, 2020-05, Vol.17 (1), p.36-36, Article 36

2020

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Human small intestinal epithelial cells differentiated from adult intestinal stem cells as a novel system for predicting oral drug absorption in humans

Drug metabolism and disposition, 2014-11, Vol.42 (11), p.1947-1954

2014

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Using human iPS cell-derived enterocytes as novel in vitro model for the evaluation of human intestinal mucosal damage

Inflammation research, 2018-12, Vol.67 (11-12), p.975-984

2018

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Simultaneous Evaluation of Membrane Permeability and UDP-Glucuronosyltransferase-Mediated Metabolism of Food-Derived Compounds Using Human Induced Pluripotent Stem Cell-Derived Small Intestinal Epithelial Cells

Drug metabolism and disposition, 2022-01, Vol.50 (1), p.17-23

2022

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SARS-CoV-2 causes dysfunction in human iPSC-derived brain microvascular endothelial cells potentially by modulating the Wnt signaling pathway

Fluids and barriers of the CNS, 2024-04, Vol.21 (1), p.32-32, Article 32

2024

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A novel perfusion culture system for screening mitochondrial toxicity in primary mouse hepatocytes

The Journal of Toxicological Sciences, 2022, Vol.47(1), pp.13-18

2022

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Development of an in vitro cholestatic drug-induced liver injury evaluation system using HepG2-hNTCP-C4 cells in sandwich configuration

Toxicology in vitro, 2019-12, Vol.61, p.104619, Article 104619

2019

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Protective Effect of Irsogladine against Aspirin-Induced Mucosal Injury in Human Induced Pluripotent Stem Cell-Derived Small Intestine

Medicina (Kaunas, Lithuania), 2022-12, Vol.59 (1), p.92

2022

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Development of a Perfusing Small Intestine–Liver Microphysiological System Device

Applied sciences, 2023-09, Vol.13 (18), p.10510

2023

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Effects of human induced pluripotent stem cell-derived intestinal organoids on colitis-model mice

Regenerative therapy, 2022-12, Vol.21, p.351-361

2022

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Differentiation of Human Induced Pluripotent Stem Cells into Functional Enterocyte-like Cells Using a Simple Method

Drug metabolism and pharmacokinetics, 2014, Vol.29 (1), p.44-51

2014

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Comparison of the inducibility of CYP mRNA exposed to typical inducers in fresh and cryopreserved cynomolgus monkey hepatocytes

Drug metabolism and pharmacokinetics, 2020-06, Vol.35 (3), p.304-312

2020

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Intracellular Toxic AGEs (TAGE) Triggers Numerous Types of Cell Damage

Biomolecules (Basel, Switzerland), 2021-03, Vol.11 (3), p.387

2021

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Ivermectin Inhibits HBV Entry into the Nucleus by Suppressing KPNA2

Viruses, 2022-11, Vol.14 (11), p.2468

2022

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Application of Human Induced Pluripotent Stem Cell-Derived Intestinal Organoids as a Model of Epithelial Damage and Fibrosis in Inflammatory Bowel Disease

Accumulation of Toxic Advanced Glycation End-Products Induces Cytotoxicity and Inflammation in Hepatocyte-Like Cells Differentiated from Human Induced Pluripotent Stem Cells

Culture methods focusing on bile canalicular formation using primary human hepatocytes in a short time

Generation of Intestinal Organoids Suitable for Pharmacokinetic Studies from Human Induced Pluripotent Stem Cells

Pharmacokinetic functions of human induced pluripotent stem cell-derived small intestinal epithelial cells

Effect of Topiroxostat on Reducing Oxidative Stress in the Aorta of Streptozotocin-Induced Diabetic Rats

Effect of Anagliptin on Vascular Injury in the Femoral Artery of Type 2 Diabetic Rats

Application of a Human Intestinal Epithelial Cell Monolayer to the Prediction of Oral Drug Absorption in Humans as a Superior Alternative to the Caco-2 Cell Monolayer

New Maintenance Culture Method for Intestinal Stem Cells Derived from Human Induced Pluripotent Stem Cells

Laminin 221 fragment is suitable for the differentiation of human induced pluripotent stem cells into brain microvascular endothelial-like cells with robust barrier integrity

Functional analysis of carboxylesterase in human induced pluripotent stem cell-derived enterocytes

Inhibition of transforming growth factor beta signaling pathway promotes differentiation of human induced pluripotent stem cell-derived brain microvascular endothelial-like cells

Human small intestinal epithelial cells differentiated from adult intestinal stem cells as a novel system for predicting oral drug absorption in humans

Using human iPS cell-derived enterocytes as novel in vitro model for the evaluation of human intestinal mucosal damage

Simultaneous Evaluation of Membrane Permeability and UDP-Glucuronosyltransferase-Mediated Metabolism of Food-Derived Compounds Using Human Induced Pluripotent Stem Cell-Derived Small Intestinal Epithelial Cells

SARS-CoV-2 causes dysfunction in human iPSC-derived brain microvascular endothelial cells potentially by modulating the Wnt signaling pathway

A novel perfusion culture system for screening mitochondrial toxicity in primary mouse hepatocytes

Development of an in vitro cholestatic drug-induced liver injury evaluation system using HepG2-hNTCP-C4 cells in sandwich configuration

Protective Effect of Irsogladine against Aspirin-Induced Mucosal Injury in Human Induced Pluripotent Stem Cell-Derived Small Intestine

Development of a Perfusing Small Intestine–Liver Microphysiological System Device

Effects of human induced pluripotent stem cell-derived intestinal organoids on colitis-model mice

Differentiation of Human Induced Pluripotent Stem Cells into Functional Enterocyte-like Cells Using a Simple Method

Comparison of the inducibility of CYP mRNA exposed to typical inducers in fresh and cryopreserved cynomolgus monkey hepatocytes

Intracellular Toxic AGEs (TAGE) Triggers Numerous Types of Cell Damage

Ivermectin Inhibits HBV Entry into the Nucleus by Suppressing KPNA2

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