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Structural Basis for Eliciting a Cytotoxic Effect in HER2-Overexpressing Cancer Cells via Binding to the Extracellular Domain of HER2

Structure (London), 2013-11, Vol.21 (11), p.1979-1991

2013

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Systemic analysis of tyrosine kinase signaling reveals a common adaptive response program in a HER2-positive breast cancer

Science signaling, 2019-01, Vol.12 (565)

2019

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Intermolecular biparatopic trapping of ErbB2 prevents compensatory activation of PI3K/AKT via RAS-p110 crosstalk

Nature communications, 2016-06, Vol.7 (1), p.11672-11672, Article 11672

2016

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Stabilization of Mdm2 via Decreased Ubiquitination Is Mediated by Protein Kinase B/Akt-dependent Phosphorylation

The Journal of biological chemistry, 2004-08, Vol.279 (34), p.35510-35517

2004

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Regulation of NDR Protein Kinase by Hydrophobic Motif Phosphorylation Mediated by the Mammalian Ste20-Like Kinase MST3

Molecular and Cellular Biology, 2005-12, Vol.25 (24), p.11019-11029

2005

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Mechanism of Activation of NDR (Nuclear Dbf2-related) Protein Kinase by the hMOB1 Protein

The Journal of biological chemistry, 2004-08, Vol.279 (34), p.35228-35235

2004

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NDR family of AGC kinases – essential regulators of the cell cycle and morphogenesis

FEBS Letters, 2003-07, Vol.546 (1), p.73-80

2003

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Regulation of NDR2 Protein Kinase by Multi-site Phosphorylation and the S100B Calcium-binding Protein

The Journal of biological chemistry, 2004-05, Vol.279 (22), p.23806-23812

2004

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Mechanism of Ca2+-mediated Regulation of NDR Protein Kinase through Autophosphorylation and Phosphorylation by an Upstream Kinase

The Journal of biological chemistry, 2003-02, Vol.278 (9), p.6710-6718

2003

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Designed ankyrin repeat proteins (DARPins) from research to therapy

Methods in enzymology, 2012, Vol.503, p.101-134

2012

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Efficient Tumor Targeting with High-Affinity Designed Ankyrin Repeat Proteins: Effects of Affinity and Molecular Size

Cancer research (Chicago, Ill.), 2010-02, Vol.70 (4), p.1595-1605

2010

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Enzyme-Linked Immunosorbent Assay for Measurement of JNK, ERK, and p38 Kinase Activities

Biological chemistry, 1998-08, Vol.379 (8-9), p.1101-1112

1998

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Enzyme-Linked Immunosorbent Assay for the Measurement of JNK Activity in Cell Extracts

Biological chemistry, 1999-05, Vol.380 (5), p.569-578

1999

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Designed Ankyrin Repeat Proteins (DARPins)

Methods in Enzymology, 2012, Vol.503, p.101-134

2012

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Structural Basis for Eliciting a Cytotoxic Effect in HER2-Overexpressing Cancer Cells via Binding to the Extracellular Domain of HER2

Systemic analysis of tyrosine kinase signaling reveals a common adaptive response program in a HER2-positive breast cancer

Intermolecular biparatopic trapping of ErbB2 prevents compensatory activation of PI3K/AKT via RAS-p110 crosstalk

Stabilization of Mdm2 via Decreased Ubiquitination Is Mediated by Protein Kinase B/Akt-dependent Phosphorylation

Regulation of NDR Protein Kinase by Hydrophobic Motif Phosphorylation Mediated by the Mammalian Ste20-Like Kinase MST3

Mechanism of Activation of NDR (Nuclear Dbf2-related) Protein Kinase by the hMOB1 Protein

NDR family of AGC kinases – essential regulators of the cell cycle and morphogenesis

Regulation of NDR2 Protein Kinase by Multi-site Phosphorylation and the S100B Calcium-binding Protein

Mechanism of Ca2+-mediated Regulation of NDR Protein Kinase through Autophosphorylation and Phosphorylation by an Upstream Kinase

Designed ankyrin repeat proteins (DARPins) from research to therapy

Efficient Tumor Targeting with High-Affinity Designed Ankyrin Repeat Proteins: Effects of Affinity and Molecular Size

Enzyme-Linked Immunosorbent Assay for Measurement of JNK, ERK, and p38 Kinase Activities

Enzyme-Linked Immunosorbent Assay for the Measurement of JNK Activity in Cell Extracts

Designed Ankyrin Repeat Proteins (DARPins)

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