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Molecular Alterations in Cutaneous Squamous Cell Carcinoma in Immunocompetent and Immunosuppressed Hosts-A Systematic Review

Cancers, 2023-03, Vol.15 (6), p.1832

2023

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Chemoprevention of keratinocyte carcinoma and actinic keratosis in solid-organ transplant recipients: Systematic review and meta-analyses

Journal of the American Academy of Dermatology, 2021-02, Vol.84 (2), p.528-530

2021

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Structure-Based Optimization of Protein Tyrosine Phosphatase 1B Inhibitors: From the Active Site to the Second Phosphotyrosine Binding Site

Journal of medicinal chemistry, 2007-09, Vol.50 (19), p.4681-4698

2007

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Matrix metalloproteinase-12 is a therapeutic target for asthma in children and young adults

Journal of allergy and clinical immunology, 2010-07, Vol.126 (1), p.70-76.e16

2010

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Treatments for AIDS/HIV‐related Kaposi sarcoma: A systematic review of the literature

International journal of dermatology, 2022-11, Vol.61 (11), p.1311-1324

2022

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Synthesis and Biological Evaluation of Quinoline Salicylic Acids As P-Selectin Antagonists

Journal of medicinal chemistry, 2007-01, Vol.50 (1), p.21-39

2007

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A Selective Matrix Metalloprotease 12 Inhibitor for Potential Treatment of Chronic Obstructive Pulmonary Disease (COPD): Discovery of (S)-2-(8-(Methoxycarbonylamino)dibenzo[b,d]furan-3-sulfonamido)-3-methylbutanoic acid (MMP408)

Journal of medicinal chemistry, 2009-04, Vol.52 (7), p.1799-1802

2009

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Treatment Outcomes of Sofosbuvir/Velpatasvir/Voxilaprevir in Direct-Acting Antiviral-Experienced Hepatitis C Virus Patients: A Systematic Review and Meta-Analysis

Viruses, 2023-06, Vol.15 (7), p.1489

2023

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Pharmacologic Inhibition of Tpl2 Blocks Inflammatory Responses in Primary Human Monocytes, Synoviocytes, and Blood

The Journal of biological chemistry, 2007-11, Vol.282 (46), p.33295-33304

2007

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Discovery of potent and selective matrix metalloprotease 12 inhibitors for the potential treatment of chronic obstructive pulmonary disease (COPD)

Bioorganic & medicinal chemistry letters, 2012-01, Vol.22 (1), p.138-143

2012

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Potent, selective, and orally bioavailable matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis

Bioorganic & medicinal chemistry, 2005-12, Vol.13 (24), p.6629-6644

2005

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Selective inhibitors of tumor progression loci-2 (Tpl2) kinase with potent inhibition of TNF-α production in human whole blood

Bioorganic & medicinal chemistry letters, 2009-07, Vol.19 (13), p.3485-3488

2009

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Inhibitors of Tumor Progression Loci-2 (Tpl2) Kinase and Tumor Necrosis Factor α (TNF-α) Production: Selectivity and in Vivo Antiinflammatory Activity of Novel 8-Substituted-4-anilino-6-aminoquinoline-3-carbonitriles

Journal of medicinal chemistry, 2007-09, Vol.50 (19), p.4728-4745

2007

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Inhibition of Tpl2 kinase and TNF-α production with 1,7-naphthyridine-3-carbonitriles: Synthesis and structure–activity relationships

Bioorganic & medicinal chemistry letters, 2005-12, Vol.15 (23), p.5288-5292

2005

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Structure-Based Optimization of Protein Tyrosine Phosphatase-1 B Inhibitors: Capturing Interactions with Arginine 24

ChemMedChem, 2008-10, Vol.3 (10), p.1525-1529

2008

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Is routine Ribavirin mandatory for genotype 3 hepatitis C compensated cirrhosis patients receiving Sofosbuvir/Velpatasvir? A meta-analysis

Journal of hepatology, 2022-07, Vol.77, p.S567

2022

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Synthesis of the dideoxynucleosides "ddC" and "CNT" from glutamic acid, ribonolactone, and pyrimidine bases

Journal of organic chemistry, 1988-09, Vol.53 (20), p.4780-4786

1988

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Discovery of Ecopladib, an Indole Inhibitor of Cytosolic Phospholipase Α2α

Journal of medicinal chemistry, 2007-03, Vol.50 (6), p.1380-1400

2007

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Synthesis and biological evaluation of sulfonamidooxazoles and β-keto sulfones: selective inhibitors of 11β-hydroxysteroid dehydrogenase type I

Bioorganic & medicinal chemistry letters, 2005-06, Vol.15 (11), p.2865-2869

2005

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Discovery of 2-[1-(4-Chlorophenyl)cyclopropyl]-3-hydroxy-8-(trifluoromethyl)quinoline-4-carboxylic Acid (PSI-421), a P-Selectin Inhibitor with Improved Pharmacokinetic Properties and Oral Efficacy in Models of Vascular Injury

Journal of medicinal chemistry, 2010-08, Vol.53 (16), p.6003-6017

2010

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Synthesis and anti-HIV activity of isonucleosides

Journal of medicinal chemistry, 1992-06, Vol.35 (13), p.2347-2354

1992

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Syntheses of the anti-AIDS drug 2',3'-dideoxycytidine from cytidine

Journal of organic chemistry, 1992-06, Vol.57 (12), p.3473-3478

1992

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Discovery of ecopladib, an indole inhibitor of cytosolic phospholipase A2α

Journal of medicinal chemistry, 2007-03, Vol.50 (6), p.1380-1400

2007

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Identification of an Orally Efficacious Matrix Metalloprotease 12 Inhibitor for Potential Treatment of Asthma

Journal of medicinal chemistry, 2009-09, Vol.52 (17), p.5408-5419

2009

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Molecular Alterations in Cutaneous Squamous Cell Carcinoma in Immunocompetent and Immunosuppressed Hosts-A Systematic Review

Chemoprevention of keratinocyte carcinoma and actinic keratosis in solid-organ transplant recipients: Systematic review and meta-analyses

Structure-Based Optimization of Protein Tyrosine Phosphatase 1B Inhibitors: From the Active Site to the Second Phosphotyrosine Binding Site

Matrix metalloproteinase-12 is a therapeutic target for asthma in children and young adults

Treatments for AIDS/HIV‐related Kaposi sarcoma: A systematic review of the literature

Synthesis and Biological Evaluation of Quinoline Salicylic Acids As P-Selectin Antagonists

A Selective Matrix Metalloprotease 12 Inhibitor for Potential Treatment of Chronic Obstructive Pulmonary Disease (COPD): Discovery of (S)-2-(8-(Methoxycarbonylamino)dibenzo[b,d]furan-3-sulfonamido)-3-methylbutanoic acid (MMP408)

Treatment Outcomes of Sofosbuvir/Velpatasvir/Voxilaprevir in Direct-Acting Antiviral-Experienced Hepatitis C Virus Patients: A Systematic Review and Meta-Analysis

Pharmacologic Inhibition of Tpl2 Blocks Inflammatory Responses in Primary Human Monocytes, Synoviocytes, and Blood

Discovery of potent and selective matrix metalloprotease 12 inhibitors for the potential treatment of chronic obstructive pulmonary disease (COPD)

Potent, selective, and orally bioavailable matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis

Selective inhibitors of tumor progression loci-2 (Tpl2) kinase with potent inhibition of TNF-α production in human whole blood

Inhibitors of Tumor Progression Loci-2 (Tpl2) Kinase and Tumor Necrosis Factor α (TNF-α) Production: Selectivity and in Vivo Antiinflammatory Activity of Novel 8-Substituted-4-anilino-6-aminoquinoline-3-carbonitriles

Inhibition of Tpl2 kinase and TNF-α production with 1,7-naphthyridine-3-carbonitriles: Synthesis and structure–activity relationships

Structure-Based Optimization of Protein Tyrosine Phosphatase-1 B Inhibitors: Capturing Interactions with Arginine 24

Is routine Ribavirin mandatory for genotype 3 hepatitis C compensated cirrhosis patients receiving Sofosbuvir/Velpatasvir? A meta-analysis

Synthesis of the dideoxynucleosides "ddC" and "CNT" from glutamic acid, ribonolactone, and pyrimidine bases

Discovery of Ecopladib, an Indole Inhibitor of Cytosolic Phospholipase Α2α

Synthesis and biological evaluation of sulfonamidooxazoles and β-keto sulfones: selective inhibitors of 11β-hydroxysteroid dehydrogenase type I

Indole Cytosolic Phospholipase A2 α Inhibitors: Discovery and in Vitro and in Vivo Characterization of 4-{3-[5-Chloro-2-(2-{[(3,4-dichlorobenzyl)sulfonyl]amino}ethyl)-1-(diphenylmethyl)-1H-indol-3-yl]propyl}benzoic Acid, Efipladib

Discovery of 2-[1-(4-Chlorophenyl)cyclopropyl]-3-hydroxy-8-(trifluoromethyl)quinoline-4-carboxylic Acid (PSI-421), a P-Selectin Inhibitor with Improved Pharmacokinetic Properties and Oral Efficacy in Models of Vascular Injury

Synthesis and anti-HIV activity of isonucleosides

Syntheses of the anti-AIDS drug 2',3'-dideoxycytidine from cytidine

Discovery of ecopladib, an indole inhibitor of cytosolic phospholipase A2α

Identification of an Orally Efficacious Matrix Metalloprotease 12 Inhibitor for Potential Treatment of Asthma

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