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Pharmacoproteomics of a Metalloproteinase Hydroxamate Inhibitor in Breast Cancer Cells: Dynamics of Membrane Type 1 Matrix Metalloproteinase-Mediated Membrane Protein Shedding

Molecular and Cellular Biology, 2008-08, Vol.28 (15), p.4896-4914

2008

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Membrane Protease Proteomics: Isotope-Coded Affinity Tag MS Identification of Undescribed MT1-Matrix Metalloproteinase Substrates

Proceedings of the National Academy of Sciences - PNAS, 2004-05, Vol.101 (18), p.6917-6922

2004

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Inflammation Dampened by Gelatinase a Cleavage of Monocyte Chemoattractant Protein-3

Science (American Association for the Advancement of Science), 2000-08, Vol.289 (5482), p.1202-1206

2000

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Noncompetitive Inhibition of Hepatocyte Growth Factor-dependent Met Signaling by a Phage-derived Peptide

Journal of molecular biology, 2009-01, Vol.385 (1), p.79-90

2009

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Characterization of the distinct collagen binding, helicase and cleavage mechanisms of matrix metalloproteinase 2 and 14 (gelatinase A and MT1-MMP): the differential roles of the MMP hemopexin c domains and the MMP-2 fibronectin type II modules in collagen triple helicase activities

The Journal of biological chemistry, 2004-10, Vol.279 (41), p.43336

2004

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Discovery of diverse and functional antibodies from large human repertoire antibody libraries

Journal of immunological methods, 2013-05, Vol.391 (1-2), p.60-71

2013

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1392 EVOLVE-104, a novel ULBP2-targeted T cell engager that integrates CD2 costimulation for the treatment of basal and squamous lineage tumors

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A1547-A1547

2023

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1386 EVOLVE-106, a T cell engager with integrated CD2 costimulation targeting B7-H4, is a precision therapy for estrogen and Her2 receptor low breast cancers

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A1541-A1541

2023

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Collagen binding properties of the membrane type-1 matrix metalloproteinase (MT1-MMP) hemopexin C domain. The ectodomain of the 44-kDa autocatalytic product of MT1-MMP inhibits cell invasion by disrupting native type I collagen cleavage

The Journal of biological chemistry, 2002-10, Vol.277 (41), p.39005-39014

2002

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Protease degradomics: mass spectrometry discovery of protease substrates and the CLIP-CHIP, a dedicated DNA microarray of all human proteases and inhibitors

Biological chemistry, 2004-06, Vol.385 (6), p.493-504

2004

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A new helper phage for improved monovalent display of Fab molecules

Journal of immunological methods, 2012-02, Vol.376 (1-2), p.46-54

2012

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The canonical methionine 392 of matrix metalloproteinase 2 (gelatinase A) is not required for catalytic efficiency or structural integrity: probing the role of the methionine-turn in the metzincin metalloprotease superfamily

The Journal of biological chemistry, 2004-04, Vol.279 (15), p.15615

2004

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Characterization of the Distinct Collagen Binding, Helicase and Cleavage Mechanisms of Matrix Metalloproteinase 2 and 14 (Gelatinase A and MT1-MMP)

The Journal of biological chemistry, 2004-10, Vol.279 (41), p.43336-43344

2004

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Abstract 3270: Mechanism of action of a novel agonist TNFR2 antibody that induces co-stimulation of T cells and promotes robust anti-tumor immunity

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.3270-3270

2019

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The Canonical Methionine 392 of Matrix Metalloproteinase 2 (Gelatinase A) Is Not Required for Catalytic Efficiency or Structural Integrity

The Journal of biological chemistry, 2004-04, Vol.279 (15), p.15615-15620

2004

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Abstract 555: A novel human TNFR2 antibody (MM-401) modulates T cell responses in anti-cancer immunity

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.555-555

2019

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A novel TNFR2 antibody induces T cell co-stimulation and promotes durable anti-tumor immunity

The Journal of immunology (1950), 2019-05, Vol.202 (1_Supplement), p.195-195.11

2019

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Abstract 3842: Design and engineering of TRAIL fusion proteins for cancer therapy

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.3842-3842

2016

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Collagen Binding Properties of the Membrane Type-1 Matrix Metalloproteinase (MT1-MMP) Hemopexin C Domain

The Journal of biological chemistry, 2002-10, Vol.277 (41), p.39005-39014

2002

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Abstract 2971: EVOLVETM: A novel T cell engager platform with integrated CD2 costimulation engineered for the treatment of immune suppressive tumors

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.2971-2971

2023

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Computer and internet use by ophthalmologists and trainees in an academic centre

Canadian journal of ophthalmology, 2009-06, Vol.44 (3), p.265-268

2009

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Matrix metalloproteinase substrate recognition, characterization and proteomic discovery

Tam, Eric M

2005

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Vulnerability and resilience in children during the COVID-19 pandemic

European child & adolescent psychiatry, 2022-01, Vol.31 (1), p.161-176

2022

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Modeling and mitigation of high-concentration antibody viscosity through structure-based computer-aided protein design

PloS one, 2020-05, Vol.15 (5), p.e0232713-e0232713

2020

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Deletion of Metabotropic Glutamate Receptors 2 and 3 (mGlu2 & mGlu3) in Mice Disrupts Sleep and Wheel-Running Activity, and Increases the Sensitivity of the Circadian System to Light

PloS one, 2015-05, Vol.10 (5), p.e0125523-e0125523

2015

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Pharmacoproteomics of a Metalloproteinase Hydroxamate Inhibitor in Breast Cancer Cells: Dynamics of Membrane Type 1 Matrix Metalloproteinase-Mediated Membrane Protein Shedding

Membrane Protease Proteomics: Isotope-Coded Affinity Tag MS Identification of Undescribed MT1-Matrix Metalloproteinase Substrates

Inflammation Dampened by Gelatinase a Cleavage of Monocyte Chemoattractant Protein-3

Noncompetitive Inhibition of Hepatocyte Growth Factor-dependent Met Signaling by a Phage-derived Peptide

Characterization of the distinct collagen binding, helicase and cleavage mechanisms of matrix metalloproteinase 2 and 14 (gelatinase A and MT1-MMP): the differential roles of the MMP hemopexin c domains and the MMP-2 fibronectin type II modules in collagen triple helicase activities

Discovery of diverse and functional antibodies from large human repertoire antibody libraries

1392 EVOLVE-104, a novel ULBP2-targeted T cell engager that integrates CD2 costimulation for the treatment of basal and squamous lineage tumors

1386 EVOLVE-106, a T cell engager with integrated CD2 costimulation targeting B7-H4, is a precision therapy for estrogen and Her2 receptor low breast cancers

Collagen binding properties of the membrane type-1 matrix metalloproteinase (MT1-MMP) hemopexin C domain. The ectodomain of the 44-kDa autocatalytic product of MT1-MMP inhibits cell invasion by disrupting native type I collagen cleavage

Protease degradomics: mass spectrometry discovery of protease substrates and the CLIP-CHIP, a dedicated DNA microarray of all human proteases and inhibitors

A new helper phage for improved monovalent display of Fab molecules

The canonical methionine 392 of matrix metalloproteinase 2 (gelatinase A) is not required for catalytic efficiency or structural integrity: probing the role of the methionine-turn in the metzincin metalloprotease superfamily

Characterization of the Distinct Collagen Binding, Helicase and Cleavage Mechanisms of Matrix Metalloproteinase 2 and 14 (Gelatinase A and MT1-MMP)

Abstract 3270: Mechanism of action of a novel agonist TNFR2 antibody that induces co-stimulation of T cells and promotes robust anti-tumor immunity

The Canonical Methionine 392 of Matrix Metalloproteinase 2 (Gelatinase A) Is Not Required for Catalytic Efficiency or Structural Integrity

Abstract 555: A novel human TNFR2 antibody (MM-401) modulates T cell responses in anti-cancer immunity

A novel TNFR2 antibody induces T cell co-stimulation and promotes durable anti-tumor immunity

Abstract 3842: Design and engineering of TRAIL fusion proteins for cancer therapy

Collagen Binding Properties of the Membrane Type-1 Matrix Metalloproteinase (MT1-MMP) Hemopexin C Domain

Abstract 2971: EVOLVETM: A novel T cell engager platform with integrated CD2 costimulation engineered for the treatment of immune suppressive tumors

Computer and internet use by ophthalmologists and trainees in an academic centre

Matrix metalloproteinase substrate recognition, characterization and proteomic discovery

Vulnerability and resilience in children during the COVID-19 pandemic

Modeling and mitigation of high-concentration antibody viscosity through structure-based computer-aided protein design

Deletion of Metabotropic Glutamate Receptors 2 and 3 (mGlu2 & mGlu3) in Mice Disrupts Sleep and Wheel-Running Activity, and Increases the Sensitivity of the Circadian System to Light

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