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Sphingosine-1-phosphate receptor 2 protects against anaphylactic shock through suppression of endothelial nitric oxide synthase in mice

Journal of allergy and clinical immunology, 2013-11, Vol.132 (5), p.1205-1214.e9

2013

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Sphingosine-1-phosphate signaling in physiology and diseases

BioFactors (Oxford), 2012-09, Vol.38 (5), p.329-337

2012

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Sphingosine-1-phosphate signaling and biological activities in the cardiovascular system

Biochimica et biophysica acta, 2008-09, Vol.1781 (9), p.483-488

2008

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Augmented sphingosine 1 phosphate receptor-1 signaling in cardiac fibroblasts induces cardiac hypertrophy and fibrosis through angiotensin II and interleukin-6

PloS one, 2017-08, Vol.12 (8), p.e0182329-e0182329

2017

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Sphingosine kinase-2 prevents macrophage cholesterol accumulation and atherosclerosis by stimulating autophagic lipid degradation

Scientific reports, 2019-12, Vol.9 (1), p.18329-14, Article 18329

2019

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Sphingosine-1-phosphate receptor-2 facilitates pulmonary fibrosis through potentiating IL-13 pathway in macrophages

PloS one, 2018-05, Vol.13 (5), p.e0197604-e0197604

2018

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S1P2, the G Protein–Coupled Receptor for Sphingosine-1-Phosphate, Negatively Regulates Tumor Angiogenesis and Tumor Growth In vivo in Mice

Cancer research (Chicago, Ill.), 2010-01, Vol.70 (2), p.772-781

2010

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Inhibitory and Stimulatory Regulation of Rac and Cell Motility by the G12/13-Rho and Gi Pathways Integrated Downstream of a Single G Protein-Coupled Sphingosine-1-Phosphate Receptor Isoform

Molecular and Cellular Biology, 2003-03, Vol.23 (5), p.1534-1545

2003

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Class II phosphatidylinositol 3-kinase α and β isoforms are required for vascular smooth muscle Rho activation, contraction and blood pressure regulation in mice

The journal of physiological sciences, 2020-03, Vol.70 (1), p.18-18, Article 18

2020

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Ca2+-Dependent Activation of Rho and Rho Kinase in Membrane Depolarization–Induced and Receptor Stimulation–Induced Vascular Smooth Muscle Contraction

Circulation research, 2003-09, Vol.93 (6), p.548-556

2003

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The Edg Family G Protein-Coupled Receptors for Lysophospholipids: Their Signaling Properties and Biological Activities

Journal of biochemistry (Tokyo), 2002-06, Vol.131 (6), p.767-771

2002

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MTMR4, a phosphoinositide‐specific 3’‐phosphatase, regulates TFEB activity and the endocytic and autophagic pathways

Genes to cells : devoted to molecular & cellular mechanisms, 2018-08, Vol.23 (8), p.670-687

2018

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Sphingosine-1-phosphate receptor-2 deficiency leads to inhibition of macrophage proinflammatory activities and atherosclerosis in apoE-deficient mice

The Journal of clinical investigation, 2010-11, Vol.120 (11), p.3979-3995

2010

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Inhibitory Regulation of Rac Activation, Membrane Ruffling, and Cell Migration by the G Protein-Coupled Sphingosine-1-Phosphate Receptor EDG5 but Not EDG1 or EDG3

Molecular and Cellular Biology, 2000-12, Vol.20 (24), p.9247-9261

2000

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Sphingosine-1-Phosphate, a Platelet-Derived Lysophospholipid Mediator, Negatively Regulates Cellular Rac Activity and Cell Migration in Vascular Smooth Muscle Cells

Circulation research, 2002-02, Vol.90 (3), p.325-332

2002

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Negative regulation of endothelial morphogenesis and angiogenesis by S1P2 receptor

Biochemical and biophysical research communications, 2006-07, Vol.346 (1), p.293-300

2006

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Sustained delivery of sphingosine-1-phosphate using poly(lactic-co-glycolic acid)-based microparticles stimulates Akt/ERK-eNOS mediated angiogenesis and vascular maturation restoring blood flow in ischemic limbs of mice

European journal of pharmacology, 2010-05, Vol.634 (1), p.121-131

2010

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Rho activation in excitatory agonist-stimulated vascular smooth muscle

American Journal of Physiology: Cell Physiology, 2001-08, Vol.281 (2), p.C571-C578

2001

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Sphingosine-1-phosphate receptor subtype-specific positive and negative regulation of Rac and haematogenous metastasis of melanoma cells

Biochemical journal, 2003-09, Vol.374 (Pt 3), p.715-722

2003

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TGFβ receptor endocytosis and Smad signaling require synaptojanin1, PI3K-C2α-, and INPP4B-mediated phosphoinositide conversions

Molecular biology of the cell, 2020-03, Vol.31 (5), p.360-372

2020

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Phosphatidylinositol 3-Kinase Class II α-Isoform PI3K-C2α Is Required for Transforming Growth Factor β-induced Smad Signaling in Endothelial Cells

The Journal of biological chemistry, 2015-03, Vol.290 (10), p.6086-6105

2015

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Sphingosine-1-Phosphate-Specific G Protein-Coupled Receptors as Novel Therapeutic Targets for Atherosclerosis

Pharmaceuticals, 2011-01, Vol.4 (1), p.117-137

2011

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Stretch Activates Jun N-terminal Kinase/Stress-activated Protein Kinase in Vascular Smooth Muscle Cells through Mechanisms Involving Autocrine ATP Stimulation of Purinoceptors

The Journal of biological chemistry, 1998-03, Vol.273 (11), p.6334-6340

1998

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Sphingosine-1-phosphate as a mediator involved in development of fibrotic diseases

Biochimica et biophysica acta, 2013-01, Vol.1831 (1), p.185-192

2013

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Sphingosine-1-phosphate signaling and cardiac fibrosis

Inflammation and Regeneration, 2013, Vol.33(2), pp.096-108

2013

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Sphingosine-1-phosphate receptor 2 protects against anaphylactic shock through suppression of endothelial nitric oxide synthase in mice

Sphingosine-1-phosphate signaling in physiology and diseases

Sphingosine-1-phosphate signaling and biological activities in the cardiovascular system

Augmented sphingosine 1 phosphate receptor-1 signaling in cardiac fibroblasts induces cardiac hypertrophy and fibrosis through angiotensin II and interleukin-6

Sphingosine kinase-2 prevents macrophage cholesterol accumulation and atherosclerosis by stimulating autophagic lipid degradation

Sphingosine-1-phosphate receptor-2 facilitates pulmonary fibrosis through potentiating IL-13 pathway in macrophages

S1P2, the G Protein–Coupled Receptor for Sphingosine-1-Phosphate, Negatively Regulates Tumor Angiogenesis and Tumor Growth In vivo in Mice

Inhibitory and Stimulatory Regulation of Rac and Cell Motility by the G12/13-Rho and Gi Pathways Integrated Downstream of a Single G Protein-Coupled Sphingosine-1-Phosphate Receptor Isoform

Class II phosphatidylinositol 3-kinase α and β isoforms are required for vascular smooth muscle Rho activation, contraction and blood pressure regulation in mice

Ca2+-Dependent Activation of Rho and Rho Kinase in Membrane Depolarization–Induced and Receptor Stimulation–Induced Vascular Smooth Muscle Contraction

The Edg Family G Protein-Coupled Receptors for Lysophospholipids: Their Signaling Properties and Biological Activities

MTMR4, a phosphoinositide‐specific 3’‐phosphatase, regulates TFEB activity and the endocytic and autophagic pathways

Sphingosine-1-phosphate receptor-2 deficiency leads to inhibition of macrophage proinflammatory activities and atherosclerosis in apoE-deficient mice

Inhibitory Regulation of Rac Activation, Membrane Ruffling, and Cell Migration by the G Protein-Coupled Sphingosine-1-Phosphate Receptor EDG5 but Not EDG1 or EDG3

Sphingosine-1-Phosphate, a Platelet-Derived Lysophospholipid Mediator, Negatively Regulates Cellular Rac Activity and Cell Migration in Vascular Smooth Muscle Cells

Negative regulation of endothelial morphogenesis and angiogenesis by S1P2 receptor

Sustained delivery of sphingosine-1-phosphate using poly(lactic-co-glycolic acid)-based microparticles stimulates Akt/ERK-eNOS mediated angiogenesis and vascular maturation restoring blood flow in ischemic limbs of mice

Rho activation in excitatory agonist-stimulated vascular smooth muscle

Sphingosine-1-phosphate receptor subtype-specific positive and negative regulation of Rac and haematogenous metastasis of melanoma cells

TGFβ receptor endocytosis and Smad signaling require synaptojanin1, PI3K-C2α-, and INPP4B-mediated phosphoinositide conversions

Phosphatidylinositol 3-Kinase Class II α-Isoform PI3K-C2α Is Required for Transforming Growth Factor β-induced Smad Signaling in Endothelial Cells

Sphingosine-1-Phosphate-Specific G Protein-Coupled Receptors as Novel Therapeutic Targets for Atherosclerosis

Stretch Activates Jun N-terminal Kinase/Stress-activated Protein Kinase in Vascular Smooth Muscle Cells through Mechanisms Involving Autocrine ATP Stimulation of Purinoceptors

Sphingosine-1-phosphate as a mediator involved in development of fibrotic diseases

Sphingosine-1-phosphate signaling and cardiac fibrosis

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